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The ECLS-SHOCK Trial: ECPR in Infarct-Related Cardiogenic Shock

RebelEM

Background: Cardiogenic shock develops in up to 10% of patients with acute myocardial infarction (AMI) and carries a 30 day mortality rate around 50%. bleeding, stroke, limb ischemia, and hemolysis). Extracorporeal Life Support in Infarct-Related Cardiogenic Shock. The evidence for this practice has been sparse until now.

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A Beginner’s Guide to Vasoactive Drug use in Children with Septic Shock

Don't Forget the Bubbles

What is Shock? Shock is defined as a type of circulatory failure where lack of oxygen leads to dysfunction of vital organs. There are many types of shock which may affect children, and management is specific to the type of shock. The overall goal in managing any cause of shock is to restore oxygen delivery to the organs.

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A discussion with interventional cardiologist Dr David Cohen on medical evidence, TAVR and stroke prevention

Sensible Medicine

I watched a case as a young doctor and came away shocked that patients survive this surgery. The other unbelievable thing about TAVR is that strokes are less common than you’d think. Early studies show that the device catches debris that would have occluded blood vessels in the brain—iow, caused stroke.

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IVC Distensibility Index vs Collapsibility Index: Using the Correct Index

RebelEM

13 That is to say nothing of the effect that the type and response to shock has on the individual patients involved in these studies. As seen in the Andromeda Shock Trial, and multiple other trials involving shocked patients, capillary return also reigns supreme regarding physical examination. Jan 2019; PMID: 30138573.

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emDOCs Podcast – Episode 85: Tricky Cases Part 1

EMDocs

Learning points: Consider differential – sepsis, thyroid storm, thalamic stroke, exertional and classic heat stroke, serotonin syndrome, neuroleptic malignant syndrome, sympathomimetic toxicity, and anticholinergics. Reference: EM@3AM – Heat Stroke Case 2: 40-year-0ld female feels unwell but no other specific complaints.

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EM@3AM: Stercoral Colitis

EMDocs

2, 8-10, 14 The clinical symptoms range from vague abdominal pain to florid septic shock and peritonitis secondary to bowel perforation. If sepsis or septic shock is present, aggressive fluid resuscitation and empiric antibiotics covering intra-abdominal flora should be administered. Abdominal pain may be absent in up to 60%.

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The Frustration of Not Being Able to Sort Signal From Noise

Sensible Medicine

A treatment to reduce stroke is tested in a clinical trial. of patients had a stroke vs 2.9% In the PROTECTED TAVR trial, the confidence intervals went from -1.7% (a lower stroke rate) to 0.5% (a higher rate of stroke). In the treatment group, 2.3% in the control arm. difference is signal or noise. Emphasis mine.)

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