PulmCCM

JANUARY 23, 2025

Various new “sepsis tests” have come to market or will soon, claiming to solve the problem of diagnostic imprecision in the early management of suspected sepsis. The lack of a reliable diagnostic test or universally accepted criteria to diagnose sepsis leads to significant challenges in clinical practice and research.

Sepsis 45

Sepsis Wellness Emergency Department Research 45

RebelEM

NOVEMBER 30, 2023

For those with sepsis, the administration of intravenous fluids (IVF) at the volumes recommended in the Surviving Sepsis Campaign (SSC) requires careful consideration of an individual’s chronic medical conditions and subsequent sensitivity to IVF. Article: Vaeli Zadeh A, Wong A, Crawford AC, Collado E, Larned JM. Am J Emerg Med.

Sepsis 122

Sepsis Fluid Resuscitation Resuscitation Administration 122

First 10 EM

JULY 29, 2024

Gestalt for sepsis? 1) The endless emphasis on rushing to hit treatment targets in sepsis or otherwise and 2) the assumption that decision instruments must be better than basic clinical judgment. This paper hits two of my biggest pet peeves in medicine.

Sepsis 109

Sepsis 109

Ken Grauer, MD

OCTOBER 10, 2024

. = Today's C ASE C ontinues: The patient was treated for sepsis. Figure-3: The ECG was repeated after beginning treatment for sepsis. Following treatment for sepsis — the patient improved clinically. Figure-4: Comparison of the repeat ECG with the initial ECG ( after treatment of sepsis ). What has happened?

EKG/ECG 423

EKG/ECG Sepsis Wellness 423

EM Literature of Note

SEPTEMBER 1, 2023

This is a short retrospective report evaluating, primarily, the Epic Sepsis Prediction Model, and the mode in which is deployed. The Epic SPM generates a “prediction of sepsis score”, calculated at 15 minute intervals, providing a continuous risk score for the development of sepsis.

Sepsis 107

Sepsis Administration Wellness 107

The Skeptics' Guide to EM

DECEMBER 14, 2024

Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. Is this pneumonia or could this be sepsis? Background: Pediatric sepsis is a major global health concern, causing an estimated 3.3 Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock.

Sepsis 103

Sepsis Shock Pediatrics Hospitals 103

Taming the SRU

JULY 24, 2024

Early Physician Gestalt Versus Usual Screening Tools for the Prediction of Sepsis in Critically Ill Emergency Patients. Ann Emerg Med 2024 Background Sepsis remains an increasingly common emergency department condition that is tied to higher morbidity and mortality across the United States as well as the rest of the world.

Sepsis 89

Sepsis Resuscitation Emergency Department Wellness 89

ACEP Now

JANUARY 5, 2025

Sepsis Robots or Sepsis Humans The proliferation of sepsis alerts in the ED has reached levels best described as obscene. The common refrain from trained clinicians: We are smarter than any computer or simple scoring system, and we can rapidly and accurately identify sepsis by ourselves, thank you very much. Pediatrics.

Sepsis 40

Sepsis Research Airway Management Stroke 40

PulmCCM

SEPTEMBER 17, 2023

The Centers for Disease Control and Prevention formally called on hospitals to develop robust sepsis care programs to systematically identify and treat sepsis, track outcomes, and improve care delivery. ” What is that, a sepsis Stasi? Unlike strokes and STEMIs, sepsis has no gold standard for diagnosis.

CDC 98

CDC Sepsis Hospitals Documentation/Coding 98

The Skeptics' Guide to EM

JULY 27, 2024

Early Physician Gestalt Versus Usual Screening Tools for the Prediction of Sepsis in Critically Ill Emergency Patients. Background: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Thus, early identification of sepsis might not be as important as sometimes stated in guidelines.

Sepsis 98

Sepsis Outcomes Documentation/Coding Hospitals 98

RebelEM

AUGUST 14, 2023

Background: Could Xuebijing (XBJ) catalyze a paradigm shift in sepsis management? XBJ is an herbal compound used in China to manage various inflammatory and infectious processes in recent years, including sepsis. This post evaluates the recent “Efficacy of Xuebijing Injection in Patients With Sepsis (EXIT-SEP)” trial.

Sepsis 98

Sepsis Outcomes Administration EMS 98

RebelEM

MAY 18, 2023

REBEL Cast Ep116: The CLOVERS Trial – Restrictive vs Liberal Fluids in Sepsis-Induced Hypotension Click here for Direct Download of the Podcast Paper: The National Heart, Lung and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network. Liberal: 14.9% Estimated Difference: -0.9%; 95% CI 04.4

Sepsis 104

Sepsis Shock Resuscitation Outcomes 104

EM Ottawa

JUNE 12, 2023

Questions and Methods: Using a cohort and QI approach, to demonstrate the effectiveness of a multidisciplinary educational intervention and EHR tool to increase sepsis bundle compliance. Findings: Overall EHR tool use increased from 23.3

Sepsis 98

Sepsis Emergency Department 98

Emergency Medicine Journal

MARCH 25, 2025

Association between time to antibiotic and mortality in patients with suspected sepsis in the emergency department: post hoc analysis of the 1-BED randomised clinical trial by Philippon et al 1 Topic: Sepsis Outcome rating: Game changer The importance of early antibiotic administration in sepsis is well recognised, yet the necessity of strict 1-hour (..)

Sepsis 52

Sepsis Emergency Department Administration Outcomes 52

The Trauma Pro

AUGUST 16, 2024

Bottom line: It’s so easy to go down the sepsis path with sick kids, especially those who can’t talk yet. Here’s the fifth law: A previously healthy child who is in arrest, or nearly so, is a victim of child abuse until proven otherwise. But healthy children tend to stay healthy, and don’t easily get sick to the point of physiologic collapse.

Pediatrics 203

Pediatrics Sepsis EMS 203

EMDocs

JANUARY 1, 2025

Guideline Updates: Corticosteroids in Sepsis, ARDS, Community-Acquired Pneumonia This post covers the SCCM guideline updates on steroids in sepsis, ARDS, and community-acquired pneumonia. Sameer Desai and Omar Abbas Ahmed Malik cover BP management in the patient with neurologic emergency.

Sepsis 75

Sepsis EMS EKG/ECG Hospitals 75

St. Emlyn

JUNE 5, 2024

St.Emlyn's - Emergency Medicine #FOAMed The latest St Emlyn's podcast with discussion about Bougies, cardiac arrest, trauma, sepsis, race and medicine and choosing with intention The post Podcast – April 2024 Monthly Round Up – Bougies, cardiac arrest, trauma, sepsis, race and medicine, and choosing with intention appeared first on (..)

Sepsis 71

Sepsis 71

EMDocs

JANUARY 11, 2025

Clinical exam: 2, 3, 9 Abdominal distension and tenderness Nausea and vomiting Stool present in the rectal vault Peritonitis may be accompanied by hemodynamic instability in the case of sepsis. 2-4, 6 If there is a concern for perforation or sepsis, surgical consultation, blood cultures, empiric antibiotics, and fluids are recommended.

EMS 98

EMS Sepsis Shock Fluid Resuscitation 98

PulmCCM

JUNE 3, 2024

Acetaminophen (paracetamol): Wikipedia Over the past 30 years, dozens of chemical compounds have been tested as therapies for sepsis. What if all the while, an effective sepsis treatment was hiding in plain sight right there on the PRN medication list?

Sepsis 52

Sepsis Outcomes Academics Hospitals 52

PulmCCM

MAY 16, 2024

The FDA approved the first-ever AI-powered electronic medical record-based prediction model for sepsis: The Sepsis Immunoscore, by Prenosis. If you look under the hood, it suffers from the same fundamental limitation as all the rest: the lack of a reference standard (gold standard) for diagnosing sepsis.

Sepsis 52

Sepsis Operations Hospitals 52

Taming the SRU

DECEMBER 17, 2024

There is substantial evidence that IV fluids can be beneficial in patients with sepsis complicated by hypotension and labor. Patients receiving maintenance fluids are hemodynamically stable, but they are unable to orally meet their daily fluid and electrolyte requirements.

Dehydration 84

Dehydration Fluid Resuscitation Administration Resuscitation 84

Board Bombs

SEPTEMBER 10, 2023

We're covering what's important in sepsis care. Sepsis: burn the stopwatches. We're covering what's important in sepsis care. Sepsis: burn the stopwatches. Take a guess what we won't be covering. It begins with an L and ends in -actate. Want to experience the greatest in board studying? September 11th, 2023.

Burns 52

Burns Sepsis Administration Hospitals 52

Board Bombs

SEPTEMBER 10, 2023

We're covering what's important in sepsis care. Sepsis: burn the stopwatches. We're covering what's important in sepsis care. Sepsis: burn the stopwatches. Take a guess what we won't be covering. It begins with an L and ends in -actate. Want to experience the greatest in board studying? September 11th, 2023.

Burns 52

Burns Sepsis Administration Hospitals 52

Board Bombs

OCTOBER 29, 2023

In the Spirit of Halloween let's cover Pediatric Sepsis- the tricks of the trade and how to not miss infections, as well as what to know for the test. Peds Sepsis: Nightmare on Epi Street. Peds Sepsis: Nightmare on Epi Street. Want to experience the greatest in board studying? Cite this podcast as: Briggs, Blake.

Sepsis 52

Sepsis Pediatrics Wellness 52

Board Bombs

OCTOBER 29, 2023

In the Spirit of Halloween let's cover Pediatric Sepsis- the tricks of the trade and how to not miss infections, as well as what to know for the test. Peds Sepsis: Nightmare on Epi Street. Peds Sepsis: Nightmare on Epi Street. Want to experience the greatest in board studying? Cite this podcast as: Briggs, Blake.

Sepsis 52

Sepsis Pediatrics Wellness 52

The Skeptics' Guide to EM

NOVEMBER 4, 2023

Time for paediatrics to screen out sepsis “screening.” He specializes in Paediatric Emergency Medicine and is a passionate […] The post SGEM Xtra: Say What You Need to Say…but Don’t Say “Sepsis Screening” first appeared on The Skeptics Guide to Emergency Medicine. Time for paediatrics to screen out sepsis “screening.”

Sepsis 55

Sepsis Shock Hospitals 55

RebelEM

MAY 29, 2023

Background: Sepsis can induce numerous physiologic derangements. The Influence of Methylene Blue infusion on Cytokine Levels During Severe Sepsis. At the most severe end, this includes endothelial dysfunction leading to increased vascular permeability, abnormal nitric oxide metabolism, and vasodilation (i.e. septic shock).

Shock 145

Shock Fluid Resuscitation Sepsis Resuscitation 145

Pediatric EM Morsels

MARCH 29, 2024

If the patient presents in metabolic crisis and the exact diagnosis is not known, ED providers can send additional labs to help expedite the work up by obtaining : Plasma amino acids, Acylcarnitine profile, and Urine organic acids Management Goal: we want to stop the metabolic crisis and convert anabolism Remember your ABCs and O MI Sugar for your (..)

Dehydration 297

Dehydration Pediatrics Sepsis EMS 297

PulmCCM

DECEMBER 11, 2024

An excellent review article titled “Sepsis and Septic Shock” was published 4 December 2024 in the New England Journal of Medicine. health system require us to enter a diagnosis to generate payment by a health insurer, it’s worth emphasizing that sepsis is a syndrome, not a disease.

Sepsis 45

Sepsis Shock Research Wellness 45

PulmCCM

JUNE 16, 2024

Beta-lactam antibiotics are the most often-prescribed antimicrobials for sepsis in the ICU, with piperacillin-tazobactam and meropenem being the most common.

Sepsis 52

Sepsis 52

ACEP Now

JANUARY 4, 2025

An algorithm will not pick up on the subtle signs of sepsis in a patient who presents atypically. Protocols will never replace the clinician who recognizes that a patient with vague chest tightness and no other clear symptoms is actually having a silent myocardial infarction or a trauma patient who does not need a reflexive CT pan scan.

Administration 98

Administration Sepsis Emergency Department 98

Dr. Smith's ECG Blog

JANUARY 2, 2025

She was managed for sepsis with antibiotics including azithromycin, had hypotension with arterial and central lines placed and pressors. I do not see OMI here and all trops were only minimally elevated, consistent with either chronic injury from cardiomyopathy or with acute injury from sepsis. She was intubated.

EKG/ECG 116

EKG/ECG Sepsis Wellness Documentation/Coding 116

PulmCCM

APRIL 19, 2024

Your elderly patient with sepsis develops new-onset atrial fibrillation that spontaneously converts to normal sinus rhythm. Should long-term anticoagulation be prescribed at discharge?

Sepsis 52

Sepsis 52

EMDocs

APRIL 6, 2024

. #1: Phoenix Criteria – New Pediatric Sepsis Score Spoon Feed The Phoenix Sepsis Score, which is a novel clinical criterion for pediatric sepsis and septic shock developed using measures of organ dysfunction, outperforms existing IPSCC criteria for the diagnosis of pediatric sepsis and septic shock.

Sepsis 97

Sepsis Pediatrics Shock 97

Emergency Medicine Journal

OCTOBER 26, 2023

Background Ambulance services need to identify and prioritise patients with sepsis for early hospital assessment. We aimed to determine the accuracy of early warning scores alongside paramedic diagnostic impression to identify sepsis that required urgent treatment. No other score provided clearly superior accuracy to NEWS2.

Sepsis 52

Sepsis Ambulance Services Operations Hospitals 52

Don't Forget the Bubbles

NOVEMBER 27, 2023

Four-year-old Ed is being resuscitated for presumed Invasive Group A Streptococcal Sepsis from tonsilitis. In middle-to-high-income countries, after 40-60ml/kg of fluid resuscitation, the Surviving Sepsis Campaign International Guidelines recommend using vasoactive drugs. After 40ml/kg of IV 0.9% The CRT is unchanged.

Shock 143

Shock Sepsis Fluid Resuscitation Resuscitation 143

EMDocs

JUNE 15, 2024

. #2: From the Doorway – How Accurate Is Physician Gestalt in Sepsis? Spoon Feed Physician gestalt significantly outperformed existing sepsis screening tools (SIRS, qSOFA, SOFA, and MEWS) in identifying sepsis early in critically ill, undifferentiated patients’ ED courses.

Sepsis 97

Sepsis Emergency Department 97