First 10 EM

DECEMBER 16, 2024

Optimizing sepsis care, including the appropriate length of antibiotic therapy, is an important goal. So should we be willing to allow an increase in mortality to reduce total antibiotic use, as the ADAPT-Sepsis non-inferiority design seems to imply? The ADAPT-Sepsis trial) appeared first on First10EM.

Sepsis 85

Sepsis EMS 85

RebelEM

AUGUST 14, 2023

Background: Could Xuebijing (XBJ) catalyze a paradigm shift in sepsis management? XBJ is an herbal compound used in China to manage various inflammatory and infectious processes in recent years, including sepsis. This post evaluates the recent “Efficacy of Xuebijing Injection in Patients With Sepsis (EXIT-SEP)” trial.

Sepsis 96

Sepsis Outcomes Administration EMS 96

The Skeptics' Guide to EM

DECEMBER 14, 2024

Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. Is this pneumonia or could this be sepsis? Background: Pediatric sepsis is a major global health concern, causing an estimated 3.3 Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock.

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Sepsis Pediatrics Shock Hospitals 85

RebelEM

MAY 18, 2023

REBEL Cast Ep116: The CLOVERS Trial – Restrictive vs Liberal Fluids in Sepsis-Induced Hypotension Click here for Direct Download of the Podcast Paper: The National Heart, Lung and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network. Liberal: 14.9% Estimated Difference: -0.9%; 95% CI 04.4

Sepsis 95

Sepsis Shock Resuscitation Outcomes 95

EM Ottawa

JUNE 12, 2023

Questions and Methods: Using a cohort and QI approach, to demonstrate the effectiveness of a multidisciplinary educational intervention and EHR tool to increase sepsis bundle compliance. Findings: Overall EHR tool use increased from 23.3

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Sepsis Emergency Department 98

RebelEM

DECEMBER 17, 2024

Bottom Line Up Top: There doesnt appear to be a morbidity or mortality benefit to treating fever in sepsis and fever may have a protective effect. A large observational study of > 2000 patients found an association with fever at presentation and ICU survival for patients with severe sepsis or septic shock ( Sunden-Culberg 2017 ).

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Sepsis Shock EMS Emergency Department 68

The Skeptics' Guide to EM

JULY 27, 2024

Early Physician Gestalt Versus Usual Screening Tools for the Prediction of Sepsis in Critically Ill Emergency Patients. Background: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Thus, early identification of sepsis might not be as important as sometimes stated in guidelines.

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Sepsis Outcomes Documentation/Coding Hospitals 76

Taming the SRU

OCTOBER 31, 2024

Ann Emerg Med 2024; Big Picture Current screening tools for pediatric septic shock and sepsis are highly specific but lack sensitivity. This study substituted age adjusted vital sign measures and a pediatric shock index into currently existing pediatric sepsis scoring systems to create the qPS4.When TamingtheSRU. 10/31/24.

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Sepsis Shock Pediatrics Administration 72

The Trauma Pro

AUGUST 16, 2024

Bottom line: It’s so easy to go down the sepsis path with sick kids, especially those who can’t talk yet. Here’s the fifth law: A previously healthy child who is in arrest, or nearly so, is a victim of child abuse until proven otherwise. But healthy children tend to stay healthy, and don’t easily get sick to the point of physiologic collapse.

Pediatrics 203

Pediatrics Sepsis EMS 203

St. Emlyn

JUNE 5, 2024

St.Emlyn's - Emergency Medicine #FOAMed The latest St Emlyn's podcast with discussion about Bougies, cardiac arrest, trauma, sepsis, race and medicine and choosing with intention The post Podcast – April 2024 Monthly Round Up – Bougies, cardiac arrest, trauma, sepsis, race and medicine, and choosing with intention appeared first on (..)

Sepsis 71

Sepsis 71

Emergency Live

NOVEMBER 5, 2024

If not recognized and treated promptly, it can lead to irreversible organ damage and death Sepsis, an extreme inflammatory response of the body to an infection, is a serious threat to the health of infants, especially those born prematurely.

Sepsis 52

Sepsis Research 52

The Bottom Line

JANUARY 9, 2025

Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis Ware. 2024.8772 Clinical Question In critically ill adult patients with sepsis does the administration of acetaminophen compared to placebo increase the number of days alive and free of organ support to day 28? doi:10.1001/jama.2024.8772

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Sepsis Administration 65

PulmCCM

JUNE 3, 2024

Acetaminophen (paracetamol): Wikipedia Over the past 30 years, dozens of chemical compounds have been tested as therapies for sepsis. What if all the while, an effective sepsis treatment was hiding in plain sight right there on the PRN medication list?

Sepsis 52

Sepsis Outcomes Academics Hospitals 52

PulmCCM

JANUARY 23, 2025

Various new “sepsis tests” have come to market or will soon, claiming to solve the problem of diagnostic imprecision in the early management of suspected sepsis. The lack of a reliable diagnostic test or universally accepted criteria to diagnose sepsis leads to significant challenges in clinical practice and research.

Sepsis 45

Sepsis Wellness Emergency Department Research 45

PulmCCM

MAY 16, 2024

The FDA approved the first-ever AI-powered electronic medical record-based prediction model for sepsis: The Sepsis Immunoscore, by Prenosis. If you look under the hood, it suffers from the same fundamental limitation as all the rest: the lack of a reference standard (gold standard) for diagnosing sepsis.

Sepsis 52

Sepsis Operations Hospitals 52

Board Bombs

SEPTEMBER 10, 2023

We're covering what's important in sepsis care. Sepsis: burn the stopwatches. We're covering what's important in sepsis care. Sepsis: burn the stopwatches. Take a guess what we won't be covering. It begins with an L and ends in -actate. Want to experience the greatest in board studying? September 11th, 2023.

Burns 52

Burns Sepsis Administration Hospitals 52

PulmCCM

JANUARY 6, 2025

In the past decade, so-called “sepsis alerts” came out of nowhere to become a ubiquitous and resource-intensive component of inpatient medical care. “Sepsis alerts” are automated notifications that flag patients who meet certain criteria compatible with severe infection discernible from the electronic medical record.

Sepsis 45

Sepsis Documentation/Coding Hospitals Outcomes 45

Board Bombs

OCTOBER 29, 2023

In the Spirit of Halloween let's cover Pediatric Sepsis- the tricks of the trade and how to not miss infections, as well as what to know for the test. Peds Sepsis: Nightmare on Epi Street. Peds Sepsis: Nightmare on Epi Street. Want to experience the greatest in board studying? Cite this podcast as: Briggs, Blake.

Sepsis 52

Sepsis Pediatrics Wellness 52

RebelEM

MAY 29, 2023

Background: Sepsis can induce numerous physiologic derangements. The Influence of Methylene Blue infusion on Cytokine Levels During Severe Sepsis. At the most severe end, this includes endothelial dysfunction leading to increased vascular permeability, abnormal nitric oxide metabolism, and vasodilation (i.e. septic shock).

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Shock Fluid Resuscitation Sepsis Resuscitation 145

PulmCCM

DECEMBER 11, 2024

An excellent review article titled “Sepsis and Septic Shock” was published 4 December 2024 in the New England Journal of Medicine. health system require us to enter a diagnosis to generate payment by a health insurer, it’s worth emphasizing that sepsis is a syndrome, not a disease.

Sepsis 45

Sepsis Shock Research Wellness 45

PulmCCM

JUNE 16, 2024

Beta-lactam antibiotics are the most often-prescribed antimicrobials for sepsis in the ICU, with piperacillin-tazobactam and meropenem being the most common.

Sepsis 52

Sepsis 52

The Skeptics' Guide to EM

NOVEMBER 4, 2023

Time for paediatrics to screen out sepsis “screening.” He specializes in Paediatric Emergency Medicine and is a passionate […] The post SGEM Xtra: Say What You Need to Say…but Don’t Say “Sepsis Screening” first appeared on The Skeptics Guide to Emergency Medicine. Time for paediatrics to screen out sepsis “screening.”

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Sepsis Shock Hospitals 53

PulmCCM

APRIL 19, 2024

Your elderly patient with sepsis develops new-onset atrial fibrillation that spontaneously converts to normal sinus rhythm. Should long-term anticoagulation be prescribed at discharge?

Sepsis 52

Sepsis 52

Emergency Medicine Journal

OCTOBER 26, 2023

Background Ambulance services need to identify and prioritise patients with sepsis for early hospital assessment. We aimed to determine the accuracy of early warning scores alongside paramedic diagnostic impression to identify sepsis that required urgent treatment. No other score provided clearly superior accuracy to NEWS2.

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Sepsis Ambulance Services Operations Hospitals 52

Don't Forget the Bubbles

NOVEMBER 27, 2023

Four-year-old Ed is being resuscitated for presumed Invasive Group A Streptococcal Sepsis from tonsilitis. In middle-to-high-income countries, after 40-60ml/kg of fluid resuscitation, the Surviving Sepsis Campaign International Guidelines recommend using vasoactive drugs. After 40ml/kg of IV 0.9% The CRT is unchanged.

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Shock Sepsis Fluid Resuscitation Resuscitation 143

PulmCCM

NOVEMBER 1, 2024

Significant uncertainty remained, though, as we discussed further here: Another randomized trial was therefore performed, dubbed ABC-SEPSIS. ABC-SEPSIS Trial The ABC-SEPSIS trial (Gray et al Crit Care Med 2024… Read more

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Sepsis Shock Resuscitation 40

Emergency Medicine Cases

MARCH 1, 2022

The post EM Quick Hits 36 – Surviving Sepsis, Angle Closure Glaucoma, Bougies, Frostbite, Hot/Altered Patient, Central Cord Syndrome appeared first on Emergency Medicine Cases.

Sepsis 52

Sepsis EMS Fluid Resuscitation Hyperthermia / Hypothermia 52

JournalFeed

JUNE 12, 2021

We cover overuse of antibiotics for ED sepsis alerts, HEART or EDACS with hs-cTn 0-1 hour rule outs, ED-AWARENESS - paralysis awareness after RSI, thoracentesis or chest tubes in coagulopathic patients, and a review on managing the difficult airway. It’s the JournalFeed Podcast for the week of Jun 7-11, 2021.

Sepsis 52

Sepsis 52

Mount Sinai EM

JULY 27, 2023

sickle cell anemia) Hyposplenia (from atrophy, infarction, engorgement, or infiltration of the spleen in chronic dz such as thalassemias, chronic liver disease, HIV/AIDs, immune disorders, or malignancies) If splenic function is in question, you can obtain a peripheral blood smear and check for Howell-Jolly bodies.

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Sepsis Wellness Infectious Diseases 182

JournalFeed

APRIL 24, 2021

We cover leadership through change, IN midazolam for pediatric seizure, hypothermia and young infant sepsis risk, VICTAS RCT, and clinically diagnosing GHB intoxication. It’s the JournalFeed Podcast for the week of Apr 19-23, 2021.

Hyperthermia / Hypothermia 52

Hyperthermia / Hypothermia Seizures Sepsis Leadership 52

University of Maryland CC Project

JANUARY 31, 2024

Her current research focuses on improving the quality and timeliness of early sepsis care. She is interested in the organization of healthcare delivery and in optimizing the delivery of evidence-based interventions for critically ill patients.

Sepsis 45

Sepsis Hospitals Research Resuscitation 45

Broome Docs

SEPTEMBER 3, 2024

In a surprise to no one who reads First10EM, clinical judgment is better than all decision tools for sepsis Knack SKS, Scott N, Driver BE, Prekker ME, Black LP, Hopson C, Maruggi E, Kaus O, Tordsen W, Puskarich MA. Early Physician Gestalt Versus Usual Screening Tools for the Prediction of Sepsis in Critically Ill Emergency Patients.

Sepsis 95

Sepsis Emergency Department Outcomes Hospitals 95

EMDocs

APRIL 6, 2024

. #1: Phoenix Criteria – New Pediatric Sepsis Score Spoon Feed The Phoenix Sepsis Score, which is a novel clinical criterion for pediatric sepsis and septic shock developed using measures of organ dysfunction, outperforms existing IPSCC criteria for the diagnosis of pediatric sepsis and septic shock.

Sepsis 85

Sepsis Pediatrics Shock 85

Don't Forget the Bubbles

AUGUST 7, 2023

Heart rate (HR) and respiratory rate (RR) are THE major vital signs used in Advanced Paediatric Life Support ( APLS) guidance , sepsis guidelines , and Paediatric Early Warning Scores (e.g., Identify the percentage of children whose heart or respiratory rate would exceed the “severe” cut-off from the UK Sepsis Trust and NICE guidelines.

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Sepsis Pediatrics Urgent Care Emergency Department 98

Emergency Medicine Cases

OCTOBER 17, 2023

In this ECG Cases blog Dr. Jesse McLaren guides us through 10 cases, driving home the points that sepsis is a common cause of rapid Afib and diffuse ST depression with reciprocal ST elevation in aVR, myo/pericarditis is a diagnosis of exclusion, endocarditis or lyme carditis can cause AV block, PE can cause low grade fever and ECG signs of acute RV (..)

Infectious Diseases 101

Infectious Diseases EKG/ECG Sepsis EMS 101

First 10 EM

JULY 3, 2023

I think there is an interesting variety of papers this time around, from sepsis, to b t, to patient access to their own results online. The pace of these literature summaries has decreased over the years, but perhaps that means that quality has increased?

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Research Sepsis EMS 96

EMDocs

JUNE 15, 2024

. #2: From the Doorway – How Accurate Is Physician Gestalt in Sepsis? Spoon Feed Physician gestalt significantly outperformed existing sepsis screening tools (SIRS, qSOFA, SOFA, and MEWS) in identifying sepsis early in critically ill, undifferentiated patients’ ED courses.

Sepsis 84

Sepsis Emergency Department 84