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Pre-Hospital Antibiotics in Sepsis?

RebelEM

Background: Sepsis remains one of the leading causes of morbidity and mortality. Prehospital Administration of Broad-Spectrum Antibiotics for Sepsis Patients: A Systematic Review and Meta-Analysis. It is well-established that earlier recognition and treatment can lead to better outcome for these patients . Health Sci Rep 2022.

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Finally, a cure fore sepsis: Herbs

First 10 EM

Can herbs cure sepsis?

Sepsis 121
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Is procalcitonin "safe" to guide antibiotic use in patients with sepsis?

PulmCCM

A large proportion have concluded PCT is a safe and effective method to shorten antibiotic courses, including in patients with sepsis. The ADAPT-Sepsis Trial Between 2018 and 2024 at 41 centers in the U.K., Because ADAPT-Sepsis was designed as a noninferiority trial, and the authors chose (arbitrarily) a 5.4%

Sepsis 98
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Congestive Heart Failure and Sepsis: A Closer Look at Fluid Management

RebelEM

For those with sepsis, the administration of intravenous fluids (IVF) at the volumes recommended in the Surviving Sepsis Campaign (SSC) requires careful consideration of an individual’s chronic medical conditions and subsequent sensitivity to IVF. Article: Vaeli Zadeh A, Wong A, Crawford AC, Collado E, Larned JM. Am J Emerg Med.

Sepsis 120
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ECG Blog #451 — Premature Closure.

Ken Grauer, MD

. = Today's C ASE C ontinues: The patient was treated for sepsis. Figure-3: The ECG was repeated after beginning treatment for sepsis. Following treatment for sepsis — the patient improved clinically. Figure-4: Comparison of the repeat ECG with the initial ECG ( after treatment of sepsis ). What has happened?

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Gestalt is better than decision tools for identifying sepsis

First 10 EM

Gestalt for sepsis? 1) The endless emphasis on rushing to hit treatment targets in sepsis or otherwise and 2) the assumption that decision instruments must be better than basic clinical judgment. This paper hits two of my biggest pet peeves in medicine.

Sepsis 104
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Which Sepsis Alert is the Biggest Loser?

EM Literature of Note

This is a short retrospective report evaluating, primarily, the Epic Sepsis Prediction Model, and the mode in which is deployed. The Epic SPM generates a “prediction of sepsis score”, calculated at 15 minute intervals, providing a continuous risk score for the development of sepsis.

Sepsis 106