Remove Research Remove Shock Remove Wellness
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The ECLS-SHOCK Trial: ECPR in Infarct-Related Cardiogenic Shock

RebelEM

Background: Cardiogenic shock develops in up to 10% of patients with acute myocardial infarction (AMI) and carries a 30 day mortality rate around 50%. Extracorporeal Life Support in Infarct-Related Cardiogenic Shock. Many centers have attempted ECLS to achieve hemodynamic stabilization in this group of patients. Control: 53.4%

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Diastolic Shock Index: A clinically relevant predictor of poor outcome in septic shock?

Taming the SRU

Diastolic shock index and clinical outcomes in patients with septic shock. O: There was an association between increased diastolic shock index score and mortality at 90 days and performed similarly to more advanced measures of morbidity and mortality in septic shock including lactate levels and SOFA scores.

Shock 52
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Sniffing out Sepsis - Vibes vs Scoring Systems?

Taming the SRU

Ann Emerg Med 2024 Background Sepsis remains an increasingly common emergency department condition that is tied to higher morbidity and mortality across the United States as well as the rest of the world. They then tested the LASSO model using the remaining 20% of data to see how well it could detect sepsis at the same time points.

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There will be a breakthrough in AF ablation coming next week at the ESC meeting

Sensible Medicine

It was a shocking result. The SHAM-PVI trial Next weekend at the European Society of Cardiology meeting in London, a UK team of researchers will present results of the SHAM-PVI trial. What we want to know is whether that reduction in AF produces a placebo-resistant effect of improved well being.

Stroke 99
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A Strong Critical Appraisal of the CHAGASICS Trial in patients with Chagas Cardiomyopathy

Sensible Medicine

No prior studies have shown that ICDs reduce heart failure hospitalizations—on the contrary, ICDs are often associated with increased hospitalizations due to the progression of heart failure, particularly when frequent shocks are involved ( Goldenberg I et al ). No efficacy claims should be made in underpowered studies.

Shock 98
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Why Pediatric Rare Medicine is Like Timeshare Sales

Sensible Medicine

It is well-recognized that our commercial drug development process, a process that has led to so many nearly miraculous advancements, serves people with rare diseases poorly. Sensible Medicine readers appreciate a well-designed clinical trial. Here is a sample of what I have heard: “You don’t want to raise research funds?

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Single ventricle defects and the hunt for the best shunt

Don't Forget the Bubbles

But, they may present postnatally with cyanosis/hypoxaemia due to insufficient pulmonary blood flow, cardiogenic shock due to insufficient systemic blood flow, or both. Resistance provided by this pathway will have a marked bearing on how well-balanced the circulation is – it is the primary determinant of PVR.