University of Maryland CC Project

JANUARY 31, 2024

Elizabeth Munroe, MD, MSc is a clinical instructor and post-doctoral research fellow in the dvision of Pulmonary and Critical Care Medicine at the University of Michigan. Elizabeth Munroe, MD, MSc is a clinical instructor and post-doctoral research fellow in the dvision of Pulmonary and Critical Care Medicine at the University of Michigan.

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Administration Sepsis Research Outcomes 40

EMDocs

NOVEMBER 25, 2023

3: High or Low Fluid Volume in Sepsis? New Meta-analysis Spoon Feed This updated systematic review and meta-analysis showed no statistically significant difference in all-cause mortality or serious adverse events in sepsis patients given low vs higher fluid volumes.

Sepsis 56

Sepsis Emergency Department Pediatrics Academics 56

The Skeptics' Guide to EM

OCTOBER 14, 2023

She is also a member of the Don’t’ Forget the Bubbles team where she serves as the editor for the monthly research round up, Bubble WRAP. We have been reading online about something called sepsis that can be deadly. Does he have sepsis?” Specifically, heart rate and respiratory rates are used in early attempts to detect sepsis.

Pediatrics 90

Pediatrics Sepsis Urgent Care Emergency Department 90

PulmCCM

OCTOBER 30, 2023

Professional Medical Societies Call for Elimination of SEP-1 The Infectious Diseases Society of America (IDSA), along with societies for emergency medicine physicians and hospitalists, are again speaking up about the ongoing policy experiment known as the Centers for Medicare and Medicaid Severe Sepsis/Septic Shock Management Bundle (SEP-1).

Sepsis 52

Sepsis Shock Hospitals Outcomes 52

RebelEM

NOVEMBER 30, 2023

For those with sepsis, the administration of intravenous fluids (IVF) at the volumes recommended in the Surviving Sepsis Campaign (SSC) requires careful consideration of an individual’s chronic medical conditions and subsequent sensitivity to IVF. What They Did: Researchers performed a systematic review and meta-analysis.

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Sepsis Fluid Resuscitation Resuscitation Administration 119

The Trauma Pro

AUGUST 25, 2023

Unfortunately, there isn’t a lot of research material out there. We have no idea if the numbers of T- and B-cells seen and the antibody titers are actually enough to avoid overwhelming post-splenectomy sepsis. So they settled on looking at papers that analyzed immune function, typically using B-cells, T-cells, and antibodies.

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Sepsis Research Outcomes Hospitals 188

Sensible Medicine

AUGUST 14, 2024

Researchers comb through the victims’ genomes for mutations in cardiorespiratory function and autonomic arousal systems. This sort of sepsis would produce many of the common autopsy findings. Scientists have found dozens of mutations in babies with SIDS deaths , but no clear answer. Dr. Paul N.

CDC 75

CDC Sepsis Research Pediatrics 75

Medagadget

JULY 10, 2023

Researchers at the University of London have collaborated with QuantuMDx, a medtech company based in the UK, to develop a microfluidic diagnostic device for tuberculosis. To address this, these researchers have developed a microfluidic chip that can capture and concentrate these bacteria from sputum samples.

Sepsis 57

Sepsis Research 57

The Skeptics' Guide to EM

DECEMBER 11, 2021

Date: December 10th, 2021 Guest Skeptic: Dr. Carly Eastin is an Associate Professor, Division of Research and Evidence Based Medicine, Department of Emergency Medicine, University of Arkansas for Medical Sciences. Back in 2019 we were talking about Vitamin C for sepsis ( SGEM#268 ). Not much has changed over the last two years.

Sepsis 40

Sepsis Shock Outcomes Research 40

Taming the SRU

JULY 24, 2024

Early Physician Gestalt Versus Usual Screening Tools for the Prediction of Sepsis in Critically Ill Emergency Patients. Ann Emerg Med 2024 Background Sepsis remains an increasingly common emergency department condition that is tied to higher morbidity and mortality across the United States as well as the rest of the world.

Sepsis 88

Sepsis Resuscitation Emergency Department Wellness 88

RebelEM

AUGUST 14, 2023

Background: Could Xuebijing (XBJ) catalyze a paradigm shift in sepsis management? XBJ is an herbal compound used in China to manage various inflammatory and infectious processes in recent years, including sepsis. This post evaluates the recent “Efficacy of Xuebijing Injection in Patients With Sepsis (EXIT-SEP)” trial.

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Sepsis Outcomes Administration EMS 98

University of Maryland CC Project

SEPTEMBER 1, 2024

His particularly research […] Dr. Jayshil Patel is an associate professor at the Medical College of Wisconsin and a board certified physician in internal medicine, pulmonary medicine, and critical care medicine.

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Shock Research Sepsis 40

PulmCCM

DECEMBER 10, 2023

Answering this research question has been made more difficult by pip-tazo’s possible status as a pseudo-nephrotoxin (elevating creatinine levels in the blood without harming the kidneys) and frequent co-administration with vancomycin, a known nephrotoxin.

Seizures 52

Seizures Sepsis Academics Administration 52

Don't Forget the Bubbles

JANUARY 10, 2024

The factorial design chosen by Dr Maitland and her research group means that several comparisons in transfusion practice could be carried out at the same time. What were the research questions? Does the study address a clearly focused research question? N Engl J Med. 2019;381(5):407-419. Was blinding achieved?

Blood Transfusions 78

Blood Transfusions Outcomes Research Hospitals 78

Don't Forget the Bubbles

MAY 31, 2023

The patients were identified through site leads from the PERUKI research network. Because of the retrospective nature of the study, if data had not been recorded in the ED notes, it was not available to researchers. D., & Paediatric Emergency Research United Kingdom and Ireland (PERUKI) (2023). Which patients were involved?

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Emergency Department Research Documentation/Coding Outcomes 135

Thinking Critical Care

MAY 18, 2023

In 1983 I was an Englishman abroad, the London anaesthetist who was appointed to be the English anaesthetist on the Shock Team only because the outstanding candidate from Oxford had preferred to take up a job doing muscle relaxant research with Kitz and Katz in the USA. 4] The research agenda at the time was broad.

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Shock Research Sepsis Resuscitation 40

Don't Forget the Bubbles

JULY 3, 2024

We suggest this list can help you discover relevant or interesting articles for your local journal club or allow you to keep a finger on the pulse of paediatric research. Trends in C-Reactive Protein Use in Early-Onset Sepsis Evaluations and Associated Antibiotic Use. Pediatrics. 2024 Jun 18:e2023065373. Forster CS, et al. Pediatrics.

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Pediatrics Fluid Resuscitation Hospitals Research 105

Don't Forget the Bubbles

JANUARY 1, 2024

We suggest this list can help you discover relevant or interesting articles for your local journal club or allow you to keep a finger on the pulse of paediatric research. 2023 Dec 12 Pediatric Sepsis Diagnosis, Management, and Sub-phenotypes. The first one highlights the impact of the recent pandemic on children. Pawlowski TW, et al.

Pediatrics 98

Pediatrics Ultrasounds Blood Transfusions Sepsis 98

PulmCCM

MARCH 11, 2024

This is not a hot research area.) It seems like a short step from there to automate consults for lots of situations: to the intensivist for all sepsis alerts with SBP<90; to cardiology for EMR-detected abnormal heart rhythms; to GI if a nurse clicks “rectal bleeding, new” on an assessment form.

Hospice 52

Hospice Documentation/Coding Administration Hospitals 52

Don't Forget the Bubbles

MAY 8, 2024

We suggest this list can help you discover relevant or interesting articles for your local journal club or allow you to keep a finger on the pulse of paediatric research. The researchers compared children diagnosed via screening with those diagnosed after clinical symptoms appeared. Shah M, et al. 2024 Apr 12:114054. Kausch SL, et al.

Pediatrics 69

Pediatrics Emergency Department Outcomes Research 69

The Skeptics' Guide to EM

NOVEMBER 18, 2017

Fever in the Emergency Department Predicts Survival of Patients With Severe Sepsis and Septic Shock Admitted to the ICU. Fever in the Emergency Department Predicts Survival of Patients With Severe Sepsis and Septic Shock Admitted to the ICU. Following the triage sepsis pathway, recently amended to use qSOFA. Probably not.

Sepsis 52

Sepsis Emergency Department Seizures Pediatrics 52

ACEP Now

SEPTEMBER 6, 2024

You may have mastered all the latest changes affecting management of sepsis, STEMI, and opiate-use disorder, but there’s no stopping the relentless revisions to our approach to neurologic emergencies. The post The Latest Research in Neurologic Emergencies appeared first on ACEP Now. Connolly SJ, Sharma M, Cohen AT, et al.

Research 64

Research Stroke Outcomes Sepsis 64

Don't Forget the Bubbles

OCTOBER 2, 2024

We suggest this list can help you discover relevant or interesting articles for your local journal club or allow you to keep a finger on the pulse of paediatric research. Corticosteroids for Managing Pediatric Sepsis and Septic Shock: A Systematic Review and Meta-analysis. Wyrwa JM, et al. Pediatrics. 2024 Sep 1;154(3):e2023065431.

Pediatrics 52

Pediatrics Hyperthermia / Hypothermia Emergency Department Urgent Care 52

ACEP Now

JULY 7, 2024

14 Future research is needed to determine the sensitivity and specificity of this device, particularly in the ED environment, where patients may have taken medications or recreational drugs, or may have received sedative or antiepileptic medications. The Neuroscience Research Group (NeuRos). 2015;31:22-26. Neurol Clin Pract.

Seizures 52

Seizures Emergency Department Outcomes EMS 52

The Skeptics' Guide to EM

MAY 9, 2020

CAEP is the national voice of emergency medicine (EM) in Canada and provides continuing medical education, advocates on behalf of emergency physicians and their patients, supports research and strengthens the EM community. Copies of our slides can be downloaded at this link. AEM May 2020. Intensive Care Med. 2020 Mar 28. Wilson et al.

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Sepsis EMS Research Operations 40

Don't Forget the Bubbles

FEBRUARY 5, 2024

We suggest this list can help you discover relevant or interesting articles for your local journal club or allow you to keep a finger on the pulse of paediatric research. Although sedentary behaviours have been linked to decreased bone mass, there is limited research on how video gaming impacts bone health. Anagnostou A, et al.

Pediatrics 52

Pediatrics Research Resuscitation Outcomes 52

Mind The Bleep

JULY 23, 2023

Medical Differentials for Bilious Vomiting: Sepsis Incidence : 22 per 1000 liver births Cause: Most commonly group B strep which has colonised the vaginal canal. Other risk factors include prolonged rupture of membranes, preterm and maternal sepsis. Sepsis causes an ileus or functional bowel obstruction. Parikh NS, I.

Sepsis 52

Sepsis Blood Transfusions Dehydration Wellness 52

PulmCCM

OCTOBER 23, 2023

Answering this research question has been made more difficult by pip-tazo’s possible status as a pseudo-nephrotoxin (elevating creatinine levels in the blood without harming the kidneys) and frequent co-administration with vancomycin, a known nephrotoxin.

Hospitals 98

Hospitals Emergency Department COPD CDC 98

University of Maryland CC Project

JANUARY 3, 2023

Dr. Sinha’s current research interests are in using big data analytics to identify biologically-driven homogeneous subgroups within heterogeneous critical-illness syndromes, with applications in precision medicine. Sinha presents a lecture entitled "Personalized Treatments in ARDS: Can Phenotyping Help?"

Research 40

Research Sepsis 40

Don't Forget the Bubbles

JUNE 10, 2024

NEC remains a significant challenge in neonatology, prompting ongoing research and clinical trials to understand its pathogenesis better, improve prevention strategies, and develop more effective treatments. Differential diagnoses include septic ileus, and infection causes such as sepsis, meningitis and pneumonia. Hunter, C.J.,

Pediatrics 40

Pediatrics Sepsis Fluid Resuscitation Outcomes 40

Thinking Critical Care

NOVEMBER 28, 2021

So after much deliberation, we have decided and are excited to bring the fourth edition of H&R back for 2022 – we had skipped 2021 to focus on some research papers and developing some courses (Flipping the Vent and The VExUS Course), but mostly because the virtual conferencing experience simply did not measure up to the live event.

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Sepsis Airway Management Wellness Resuscitation 52

EMDocs

JULY 1, 2023

Upon further research in the 1970’s, retrospective data from autopsies of those patients showed coronary aneurysms 5 Pathophysiology: Kawasaki Disease is a vasculitis of medium sized arteries.

EMS 66

EMS Infectious Diseases Pediatrics Research 66

PulmCCM

FEBRUARY 19, 2024

In my anecdotal experience, these phrases have an impressively high positive predictive value for badness (early sepsis, often). Maybe at Shands, although patients and families almost never actually called, care teams became more attentive, knowing they might? Patient-Centered, or Pandora’s Box?

Hospitals 52

Hospitals Resuscitation Burns Documentation/Coding 52

Mind The Bleep

FEBRUARY 27, 2024

2] Since this data was published the APLS guidelines have altered to reflect these results and the need for more research in this area and now recommend the 10ml/kg boluses as above compared to the previous recommendation of 20ml/kg. saline), however more research is needed in this area. [4] Which type of fluid to use?

Fluid Resuscitation 96

Fluid Resuscitation Hospitals Dehydration Research 96

PHEM Cast

APRIL 10, 2016

[link] We hope you enjoyed our sepsis podcast. St Emlyns Induction podcast on Sepsis. A great summary of what to do when a patient with suspected sepsis first arrives in the ED. A great summary of what to do when a patient with suspected sepsis first arrives in the ED. March 2016.

Sepsis 52

Sepsis Fluid Resuscitation Resuscitation Emergency Department 52

Northwestern EM Blog

FEBRUARY 14, 2022

Mortality benefit is an extremely elusive goal in critical care research 1 but that doesn’t discount the fact that ATHOS 3 wasn’t designed to demonstrate an improvement in any patient-oriented outcome. But what does that mean to us clinically in the ED and ICU?

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Shock Resuscitation Sepsis Fluid Resuscitation 52

Don't Forget the Bubbles

MAY 28, 2024

Hence, PPHN can be idiopathic or secondary to a variety of conditions such as meconium aspiration syndrome , respiratory distress syndrome, sepsis, asphyxia and congenital diaphragmatic hernia. Ongoing research and innovation are critical to develop strategies to reduce disease burden further. Early identification is key!

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Sepsis Ultrasounds Pediatrics Research 52