Taming the SRU

JULY 24, 2024

Early Physician Gestalt Versus Usual Screening Tools for the Prediction of Sepsis in Critically Ill Emergency Patients. Ann Emerg Med 2024 Background Sepsis remains an increasingly common emergency department condition that is tied to higher morbidity and mortality across the United States as well as the rest of the world.

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RebelEM

AUGUST 14, 2023

Background: Could Xuebijing (XBJ) catalyze a paradigm shift in sepsis management? XBJ is an herbal compound used in China to manage various inflammatory and infectious processes in recent years, including sepsis. This post evaluates the recent “Efficacy of Xuebijing Injection in Patients With Sepsis (EXIT-SEP)” trial.

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First 10 EM

SEPTEMBER 9, 2024

Welcome back to another research roundup. In a surprise to no one who reads First10EM, clinical judgment […] The post The September 2024 Research Roundup appeared first on First10EM. This edition doesn’t have any immediate practice changers, but I think there are some very important topics.

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PHEM Cast

APRIL 10, 2016

[link] We hope you enjoyed our sepsis podcast. St Emlyns Induction podcast on Sepsis. A great summary of what to do when a patient with suspected sepsis first arrives in the ED. A great summary of what to do when a patient with suspected sepsis first arrives in the ED. March 2016.

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RebelEM

MAY 29, 2023

Background: Sepsis can induce numerous physiologic derangements. Most of the research on the use of MB has been in patients with vasoplegia following cardiopulmonary bypass. Our study supports further research regarding MB in larger randomized clinical trials.” septic shock). Through these mechanisms it restores vasoregulation.

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PulmCCM

DECEMBER 11, 2024

An excellent review article titled “Sepsis and Septic Shock” was published 4 December 2024 in the New England Journal of Medicine. health system require us to enter a diagnosis to generate payment by a health insurer, it’s worth emphasizing that sepsis is a syndrome, not a disease.

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EMDocs

JANUARY 25, 2025

PCP Pneumonia, Sepsis) can be discharged with initiation of Antiretroviral Therapy in consultation with Infectious Disease (ID) physician with full ID evaluation outpatient. BioMed Research International, 2020, 1-10. Journal of Research in Pharmacy Practice, 6(1), 31. Journal of Blood Medicine, Volume 13, 243-253. link] Lu, W.,

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EMS Infectious Diseases Allergic Reactions Fluid Resuscitation 94

The Trauma Pro

AUGUST 25, 2023

Unfortunately, there isn’t a lot of research material out there. We have no idea if the numbers of T- and B-cells seen and the antibody titers are actually enough to avoid overwhelming post-splenectomy sepsis. So they settled on looking at papers that analyzed immune function, typically using B-cells, T-cells, and antibodies.

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University of Maryland CC Project

JANUARY 31, 2024

Her current research focuses on improving. Her current research focuses on improving the quality and timeliness of early sepsis care. Jen Ginestra, MD, MSHP is an instructor of medicine in the department of Pulmonary & Critical Care Medicine at the University of Pennsylvania.

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Taming the SRU

APRIL 17, 2024

The surviving sepsis guidelines weakly recommend invasive arterial blood pressure monitoring (IABP) over noninvasive blood pressure monitoring (NIBP) with a blood pressure cuff supported by low quality evidence.(1) Surviving sepsis campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Crit Care Med.

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Sepsis Research Stroke Academics 94

First 10 EM

APRIL 10, 2023

Apparently this paper was entirely fictional (or perhaps the […] The post Research Roundup (April 2023) appeared first on First10EM. Obviously the study was satire, and did an excellent job in making us laugh, but most satire studies (like those in the Christmas edition of the BMJ) are real studies.

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Research Sepsis Fractures EMS 52

The Skeptics' Guide to EM

OCTOBER 14, 2023

She is also a member of the Don’t’ Forget the Bubbles team where she serves as the editor for the monthly research round up, Bubble WRAP. We have been reading online about something called sepsis that can be deadly. Does he have sepsis?” Specifically, heart rate and respiratory rates are used in early attempts to detect sepsis.

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Pediatrics Sepsis Urgent Care Emergency Department 105

ACEP Now

SEPTEMBER 6, 2024

You may have mastered all the latest changes affecting management of sepsis, STEMI, and opiate-use disorder, but there’s no stopping the relentless revisions to our approach to neurologic emergencies. The post The Latest Research in Neurologic Emergencies appeared first on ACEP Now. Connolly SJ, Sharma M, Cohen AT, et al.

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Research Stroke Outcomes Sepsis 49

ACEP Now

MARCH 6, 2024

Every year, the volume of published research continues to outpace capacity to consume. A Myriad of Infectious Disease Papers The use of steroids in severe sepsis remains challenging, primarily as proper patient selection is necessary to tease out those with the greatest likelihood of benefit. Gotta catch ‘em all!” percent to 38.3

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Research Airway Management Stroke Outcomes 52

Sensible Medicine

JULY 29, 2024

Yet the failure of the hospital readmission penalty policy and sepsis protocols expose the risks of implementing a policy because it sounds good. Dr. Sarah Miller, an economist in the University Michigan business school, led the second trial, named the Open Research Unconditional Income Study or ORUS study.

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JournalFeed

MARCH 23, 2024

Friday Spoon Feed: In this retrospective study of ED physicians in one state, researchers found statistically significant differences in admission rates among clinicians but little consistency in admission tendencies across multiple conditions.

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Sepsis Shock Research 52

EB Medicine

OCTOBER 1, 2018

This month, we’ll be talking Updates and Controversies in the Early Management of Sepsis and Septic Shock. We have a special episode for you this month… We’ve brought Dr. Jeremy Rose, one of the peer reviewers, and a sepsis expert, on with us to talk through the content this month. Jeff : Sepsis chair. Sepsis-3!!

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Don't Forget the Bubbles

MAY 31, 2023

The patients were identified through site leads from the PERUKI research network. Because of the retrospective nature of the study, if data had not been recorded in the ED notes, it was not available to researchers. D., & Paediatric Emergency Research United Kingdom and Ireland (PERUKI) (2023). Which patients were involved?

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Taming the SRU

MARCH 30, 2023

Many clinical decision-making tools have been developed and validated in their use to identify and define those who are in sepsis or septic shock, as well as predict a patient’s overall risk of morbidity and mortality, including tools like the SIRS criteria and SOFA score. DSI levels were then distributed into 5 different quintiles.

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Shock Outcomes Sepsis Resuscitation 52

AENJ: Current Issue

MAY 8, 2024

This column on translating research into practice is crafted to offer advanced practice registered nurses an analysis of current research topics that hold practical relevance for emergency care settings.

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Emergency Department Outcomes Sepsis Research 40

RebelEM

OCTOBER 5, 2023

Background: Community-acquired pneumonia (CAP) can lead to pulmonary and systemic inflammation, resulting in impaired gas exchange, sepsis, organ failure, and an increased risk of death. Strengths: The investigators framed a research question centered on patient outcomes, ensuring the study’s relevance and practicality.

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Research Outcomes Administration Shock 94

PulmCCM

OCTOBER 30, 2023

Professional Medical Societies Call for Elimination of SEP-1 The Infectious Diseases Society of America (IDSA), along with societies for emergency medicine physicians and hospitalists, are again speaking up about the ongoing policy experiment known as the Centers for Medicare and Medicaid Severe Sepsis/Septic Shock Management Bundle (SEP-1).

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Sepsis Shock Hospitals Infectious Diseases 52

University of Maryland CC Project

JANUARY 31, 2024

Elizabeth Munroe, MD, MSc is a clinical instructor and post-doctoral research fellow in the dvision of Pulmonary and Critical Care Medicine at the University of Michigan. Elizabeth Munroe, MD, MSc is a clinical instructor and post-doctoral research fellow in the dvision of Pulmonary and Critical Care Medicine at the University of Michigan.

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The Skeptics' Guide to EM

NOVEMBER 18, 2017

Fever in the Emergency Department Predicts Survival of Patients With Severe Sepsis and Septic Shock Admitted to the ICU. Fever in the Emergency Department Predicts Survival of Patients With Severe Sepsis and Septic Shock Admitted to the ICU. Following the triage sepsis pathway, recently amended to use qSOFA. Probably not.

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Sepsis Emergency Department Seizures Pediatrics 52

The Skeptics' Guide to EM

SEPTEMBER 28, 2019

Dr. Carly Eastin is an Associate Professor, Division of Research and Evidence Based Medicine, Department of Emergency Medicine, University of Arkansas for Medical Sciences. But you remember seeing in the news there was a study claiming vitamin C could cure sepsis. You wonder if giving vitamin C will affect her outcome?

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Sepsis Shock Outcomes Stroke 52

Don't Forget the Bubbles

JANUARY 10, 2024

The factorial design chosen by Dr Maitland and her research group means that several comparisons in transfusion practice could be carried out at the same time. What were the research questions? Does the study address a clearly focused research question? N Engl J Med. 2019;381(5):407-419. Was blinding achieved?

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Medagadget

JULY 10, 2023

Researchers at the University of London have collaborated with QuantuMDx, a medtech company based in the UK, to develop a microfluidic diagnostic device for tuberculosis. To address this, these researchers have developed a microfluidic chip that can capture and concentrate these bacteria from sputum samples.

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Don't Forget the Bubbles

MAY 17, 2023

We suggest this list can help you discover relevant or interesting articles for your local journal club or allow you to keep a finger on the pulse of paediatric research. Original clinical studies The impact of the early onset neonatal sepsis calculator on antibiotic initiation: a single center study in Israel. Tritos NA, et al.

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Pediatrics X-Ray Interpretation Sepsis Fractures 72

The Skeptics' Guide to EM

DECEMBER 11, 2021

Date: December 10th, 2021 Guest Skeptic: Dr. Carly Eastin is an Associate Professor, Division of Research and Evidence Based Medicine, Department of Emergency Medicine, University of Arkansas for Medical Sciences. Back in 2019 we were talking about Vitamin C for sepsis ( SGEM#268 ). Not much has changed over the last two years.

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Sepsis Shock Outcomes Academics 40

The Skeptics' Guide to EM

OCTOBER 23, 2021

She is the cofounder of FOAMcast and a pulmonary embolism and implementation science researcher. Dr. Westafer serves as the Social Media Editor and research methodology editor for Annals of Emergency Medicine. Lauren also recently won the SAEM FOAMed Excellence in Education Award. Excluded: Unstable comorbidity (e.g.

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Emergency Department Sepsis Hospitals Research 52

EMDocs

JULY 1, 2023

Upon further research in the 1970’s, retrospective data from autopsies of those patients showed coronary aneurysms 5 Pathophysiology: Kawasaki Disease is a vasculitis of medium sized arteries.

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EMS Infectious Diseases Pediatrics Research 92

The Skeptics' Guide to EM

JULY 16, 2022

Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit. Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit. Background: Dr. Paul Marik got the critical care world all excited when he claimed a Vitamin C cocktail (Vitamin C, hydrocortisone and thiamine) as a possible cure for sepsis.

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Sepsis Shock Outcomes EMS 40

Pediatric Emergency Playbook

APRIL 1, 2016

Lactate A sick child with sepsis syndrome? In the adult literature, we know that a lactate level above 4 mmol/L in patients with severe sepsis was associated with the need for critical care. The acute recognition and treatment of sepsis is first and foremost, clinical. The short answer – yes.

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Pediatrics Sepsis Shock Outcomes 52

PulmCCM

DECEMBER 10, 2023

Answering this research question has been made more difficult by pip-tazo’s possible status as a pseudo-nephrotoxin (elevating creatinine levels in the blood without harming the kidneys) and frequent co-administration with vancomycin, a known nephrotoxin.

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Broome Docs

AUGUST 2, 2022

Vitamin C in sepsis: STOP IT, we do not LOVE IT Lamontagne F, Masse MH, Menard J, et al; LOVIT Investigators and the Canadian Critical Care Trials Group. Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit. PMID: 35704292 Bottom line: Sepsis is not treated with vitamins. N Engl J Med. Ann Intern Med.

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Northwestern EM Blog

JANUARY 24, 2022

Acidosis Acidosis in shock states can present from multiple different sources, including sepsis, hypoxemia, ingestions, hyperlactatemia from hypoperfusion, amongst others. Hypothyroidism and Adrenal Insufficiency in Sepsis and Hemorrhagic Shock. Critical Care Research and Practice. Curr Opin Crit Care. 2008;14:379-83.

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Thinking Critical Care

MAY 18, 2023

In 1983 I was an Englishman abroad, the London anaesthetist who was appointed to be the English anaesthetist on the Shock Team only because the outstanding candidate from Oxford had preferred to take up a job doing muscle relaxant research with Kitz and Katz in the USA. 4] The research agenda at the time was broad.

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