Remove Outcomes Remove Resuscitation Remove Sepsis
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Sepsis Screening Decreases Mortality. Well, not really.

Sensible Medicine

This comment might be one of the reasons I’ve been skeptical of sepsis screening. Sepsis screening, for me, comes in many different flavors -- from EMR alerts based on lab and vital sign data to anyone being able to draw a lactate or call an RRT. Outcomes and patients The primary outcome was 90-day in-hospital mortality.

Sepsis 98
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Congestive Heart Failure and Sepsis: A Closer Look at Fluid Management

RebelEM

For those with sepsis, the administration of intravenous fluids (IVF) at the volumes recommended in the Surviving Sepsis Campaign (SSC) requires careful consideration of an individual’s chronic medical conditions and subsequent sensitivity to IVF. Outcomes: Primary Outcome: In-hospital mortality. Am J Emerg Med.

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REBEL Cast Ep116: The CLOVERS Trial – Restrictive vs Liberal Fluids in Sepsis-Induced Hypotension

RebelEM

Background: IV fluids are part of the standard resuscitation bundle in septic shock, however it is unclear if they provide a significant benefit. The secondary outcome of mortality was not statistically different however numerically favored the early use of norepinephrine. This resulted in better shock control by 6hrs (76.1%

Sepsis 104
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The 90th Bubble wrap DFTB X The Bridge

Don't Forget the Bubbles

This was a secondary analysis of the Management and Outcome of Fever in Children in Europe (MOFICHE) study. The primary outcome measure was SBI, and 1854 children included were diagnosed with an SBI. Reviewed by Dr Faye Leggott Article 2: Does fluid overload increase mortality in children with sepsis? Whats it about?

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Adjunctive Methylene Blue in Septic Shock?

RebelEM

Background: Sepsis can induce numerous physiologic derangements. Judicious fluid resuscitation is indicated in patients with signs of hypo perfusion but is often inadequate necessitating the administration of vasoactive medications. septic shock). NaCl over 6hrs once daily x3 doses Placebo: 500mL of 0.9% 95% CI 15.4 95% CI 15.4

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EM@3AM: Stercoral Colitis

EMDocs

Clinical exam: 2, 3, 9 Abdominal distension and tenderness Nausea and vomiting Stool present in the rectal vault Peritonitis may be accompanied by hemodynamic instability in the case of sepsis. 2-4, 6 If there is a concern for perforation or sepsis, surgical consultation, blood cultures, empiric antibiotics, and fluids are recommended.

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Putting Clinical Gestalt to Work in the Emergency Department

ACEP Now

Caring for critically ill patients with limited information requires snap assessments and judgements for timely resuscitation and efficient emergency department throughput. In this study, clinical gestalt is not only fast, but accurate for the benefit of timely resuscitation and intervention. New York: Penguin Books. Ann Emerg Med.