Medagadget

MAY 26, 2023

Researchers at the Hubrecht Institute in the Netherlands have developed a biobank of cancer organoids using tissue samples obtained from head and neck cancer patients. Organoids are tiny 3D tissue constructs that have been created by researchers to mimic a specific tissue, or in this case, a type of cancer.

Outcomes 93

Outcomes Research 93

Emergency Medicine Journal

JULY 22, 2024

Background The outcomes of patients who call an ambulance but are discharged at scene reflect the safety and quality of emergency medical service (EMS) care. While previous studies have examined the outcomes of patients discharged at scene, none have specifically focused on paramedic-initiated discharge.

Outcomes 98

Outcomes EMS Hospitals Research 98

ACEP Now

JANUARY 5, 2025

1 The primary outcome was the frequency of observed hypoxemia, defined as any pulse oximetry reading below 85 percent. Serious patient-oriented outcomes such as cardiac arrest were rare, but almost all occurred in the oxygen mask cohort. The obvious winner was NIPPV, whose 9.1

Sepsis 40

Sepsis Research Airway Management Stroke 40

St. Emlyn

MARCH 8, 2024

St.Emlyn's - Emergency Medicine #FOAMed Is mechanical CPR associated with improved or worse outcomes in in-hospital cardiac arrest. FOAMed @stemlyns The post Is mCPR associated with better outcomes for in-hospital cardiac arrest? St Emlyn’s appeared first on St.Emlyn's.

Outcomes 124

Outcomes Hospitals CPR Research 124

St. Emlyn

JANUARY 13, 2025

Ideal for clinicians and researchers aiming to optimise anaesthesia practices and enhance patient outcomes in emergency settings. With insights into drug protocols, administration methods, and governance, the article highlights challenges and opportunities for standardisation in prehospital care.

Administration 60

Administration Research Outcomes 60

Sensible Medicine

FEBRUARY 18, 2025

Treatment failure, the primary outcome, was defined differently for each group: A need for subsequent appendectomy in the antibiotic group and negative appendectomy for the controls. An RCT measures an intervention’s effect on a single outcome. In this study, different outcomes were assessed for each group.

Outcomes 91

Outcomes Research Emergency Department Pediatrics 91

American Medical Compliance

NOVEMBER 29, 2024

Unlike traditional methods that rely on periodic fingerstick tests, CGM offers real-time insights into glucose levels, trends, and fluctuations, empowering proactive management and improving patient outcomes. However, to maximize its benefits, healthcare providers must be well-versed in the technology.

Outcomes 105

Outcomes Wellness Operations Pediatrics 105

Sensible Medicine

JULY 30, 2024

In this context, the Canary Prostate Active Surveillance Study ( PASS ) sought to understand the long-term outcomes of active surveillance. Question What are the long-term outcomes for patients with favorable risk prostate cancer managed with protocol-directed active surveillance?

Outcomes 102

Outcomes Research 102

Pediatric EM Morsels

JULY 28, 2023

Kendra Jackson and Rebecca Raffler While we’ve gotten to snack on a Morsel on this subject before , new guidelines and research surrounding DKA and cerebral edema have come to light since the first go ‘round! The Pediatric Emergency Medicine Collaborative Research Commitee. Authors: Drs. Then we’ve likely got DKA. PMID: 12461495.

Fluid Resuscitation 246

Fluid Resuscitation Pediatrics Resuscitation Research 246

The Skeptics' Guide to EM

MARCH 1, 2025

She is the cofounder of FOAMcast and a pulmonary embolism and implementation science researcher. Dr. Westafer serves as the Social Media Editor and a research methodology editor for Annals of Emergency Medicine. Intervention: Age-adjusted or standard (<500) cut off for d-dimer Comparison: None Outcome:

Allergic Reactions 75

Allergic Reactions Research Emergency Department Ultrasounds 75

Don't Forget the Bubbles

OCTOBER 30, 2023

Except there’s one problem… I never had anyone actually teach me how to read a research paper… Do I read it like a book? Most traditional research papers have these key sections. The problem is that most research studies are imperfect and have biases. Pay attention to what primary and secondary outcomes were specified.

Research 144

Research Outcomes 144

Dr. Smith's ECG Blog

NOVEMBER 27, 2024

3) some measurement of ST upward concavity (the less concave, the more likely to be HATW 4) The variables and formulas will be different for precordial leads vs. limb leads The Queen of Hearts is exceptional at recognizing hyperacute T-waves.

EKG/ECG 133

EKG/ECG Research Outcomes Wellness 133

Emergency Medicine Journal

JULY 22, 2024

Research focusing on the unique needs of children and their families has improved patient outcomes in the ED, outpatient and inpatient settings. However, little research has been done on optimising patient outcomes after ED discharge.

Outcomes 52

Outcomes Research 52

The Skeptics' Guide to EM

NOVEMBER 9, 2024

Background: In recent years, large language models (LLMs), such as GPT-4 and Claude, have shown remarkable potential in automating and improving various aspects of medical research. eligibility criteria, recruitment, primary outcome, etc.) More importantly, how can they augment human decision-making in medical research?

Research 58

Research Emergency Department Outcomes Hospitals 58

St. Emlyn

JANUARY 27, 2025

St.Emlyn's - Emergency Medicine #FOAMed What is the impact of physician-led interprofessional pre-hospital teams on survival and mortality outcomes for critically ill and injured patients. The post JC: Do physician led prehospital teams improve outcomes? appeared first on St.Emlyn's.

Outcomes 63

Outcomes Hospitals Research Resuscitation 63

Sensible Medicine

OCTOBER 19, 2023

To the editor: Subpart D of 45 Code of Federal Regulations Section §46.404 states that research involving children should not entail greater than minimal risk, meaning that harm or discomfort should be no greater than those encountered in everyday life. Yet the journal refuses to print it.

Documentation/Coding 129

Documentation/Coding Pediatrics Research Outcomes 129

Emergency Medicine Journal

AUGUST 21, 2024

Feasibility outcomes were recruitment, retention and adherence. Clinical end points (pulmonary complications, pain and frailty-specific outcomes) and patient questionnaires were collected to determine feasibility of data collection and inform health economic scoping. Pain and some frailty-specific outcomes were not feasible to collect.

Fractures 97

Fractures Research Outcomes Hospitals 97

The Skeptics' Guide to EM

OCTOBER 5, 2024

She is the co-founder of FOAMcast and a pulmonary embolism and implementation science researcher. Dr. Westafer serves as the Social Media Editor and a research methodology editor for the Annals of Emergency Medicine. Secondary Outcome: The device's diagnostic accuracy in detecting LVO stroke.

Stroke 115

Stroke EMS Outcomes Research 115

The Skeptics' Guide to EM

DECEMBER 16, 2023

Background: Patient experiences of care are associated with health outcomes and may impact perspectives of ED care and the patient recovery process.(1-5) Microaggressions are discriminatory behaviors that may be subtle or unintentional but may disempower affected individuals leading to differential care and worse healthcare outcomes.(7-10)

Emergency Department 127

Emergency Department Research Outcomes 127

Pediatric EM Morsels

JULY 21, 2023

Motor Fingernail bed pressure with a pencil first If flexion outcome, then apply painful stimulus to neck or head (trapezius or supraorbital notch) to look for localization Spinal reflex can result in a falsely elevated score if lower extremity pain induced Verbal Orientated- Able to answer all questions. A practical scale. PMID: 4136544.

Head Injuries 246

Head Injuries Pediatrics Outcomes Shock 246

Sensible Medicine

SEPTEMBER 16, 2024

The New York Times’ piece included this line: Now, a large-scale study from the Feinstein Institutes for Medical Research in Manhasset, N.Y., The primary outcome was death in the hospital. Other outcomes included respiratory complications (pneumonia), intubation and hospital length of stay (LOS).

Outcomes 126

Outcomes Hospitals Research 126

The Trauma Pro

OCTOBER 6, 2023

Although many of these injuries were managed within hours, a growing number were delayed by a few days to improve outcomes. The first is from an international research group that searched the usual databases and initially found 921 records. It is from a group of researchers from our big Boston trauma centers and the Netherlands.

Head Injuries 147

Head Injuries Research Hospitals Resuscitation 147

RebelEM

JUNE 1, 2023

Post-ROSC management is nuanced and challenging but helps to ensure good outcomes. In theory, rapid identification of the underlying cause should improve outcomes by allowing clinicians to tailor management. Diagnostic yield, safety, and outcomes of Head-to-pelvis sudden death CT imaging in post arrest care: The CT FIRST cohort study.

Outcomes 145

Outcomes Resuscitation Hospitals CPR 145

Sensible Medicine

MARCH 19, 2024

EBM model, individual clinical decisions should be based on three components – “patient’s clinical state and circumstances”, “patient’s preferences and actions” and “research evidence” – and clinical expertise plays a central role in integrating these components (Figure 1).

Research 143

Research Outcomes 143

Don't Forget the Bubbles

DECEMBER 25, 2023

Interpreting Research Outcomes with a Little Bathroom Humour You have learned a method for how to read a research paper , and now you are faced with a bunch of outcomes. There are primary, secondary, composite , and safety outcomes. What are these outcomes? What should you focus on?

Research 83

Research Outcomes Fractures Pediatrics 83

RebelEM

MAY 27, 2024

It is the first research paper to explore the synergistic effects of combining MVM and IV Adenosine in treating PSVT. The primary outcomes are patient-centered and objectively measured, potentially ensuring relevance and reliability. The unblinded nature of the study could influence outcomes due to observer bias.

Outcomes 137

Outcomes Research Operations Hospitals 137

ACEP Now

SEPTEMBER 6, 2024

In this case, because outcomes are so dismal already from large-vessel occlusions, there is some benefit to treatment with tenecteplase, 33 percent versus 24 percent advantage for good or excellent functional outcomes. More troubling, however, were the poor patient-oriented outcomes observed in the trial. N Engl J Med.

Research 49

Research Stroke Outcomes Sepsis 49

RebelEM

SEPTEMBER 7, 2023

More research is needed to inform preventive treatment strategies for seizures in patients with spontaneous intracerebral hemorrhage (ICH). OUTCOMES Primary: Occurrence of at least one clinical or electrographic seizure recorded on continuous EEG within 72 hours after inclusion. The primary outcome was patient-oriented.

Seizures 129

Seizures Stroke Outcomes Research 129

ACEP Now

MARCH 6, 2024

Every year, the volume of published research continues to outpace capacity to consume. 4 Repeated trials have not shown alteplase to have any signal of better outcomes, nor tenecteplase to have an association with increased adverse events. Gotta catch ‘em all!” How Best to Stop the Bleeding in Trauma? percent to 38.3

Research 52

Research Airway Management Stroke Outcomes 52

RebelEM

NOVEMBER 30, 2023

What They Did: Researchers performed a systematic review and meta-analysis. Outcomes: Primary Outcome: In-hospital mortality. Secondary Outcomes: Delayed hypotension, increased ICU stay, and other relevant outcomes. The study was conducted according to PRISMA guidelines. 2.89, p = 0.01.

Sepsis 122

Sepsis Fluid Resuscitation Resuscitation Administration 122

Sensible Medicine

AUGUST 3, 2024

What was the outcome? The outcome was not illness. ” To reiterate, the outcome was clicking the right boxes in an online survey. This study's surrogate treatment and outcome are so many steps away from the causal chain we cared about. The control group was explicitly instructed not to wear masks. What did we learn?

Documentation/Coding 144

Documentation/Coding Outcomes Research 144

The Skeptics' Guide to EM

JULY 2, 2023

He is the Creator and founder of REBEL EM, a free, critical appraisal blog that tries to cut down knowledge translation gaps of research to bedside clinical practice ( [link] ). Most of the times the RCTs we critically appraised did not demonstrate superiority for their primary outcome. Prehospital Tranexamic Acid for Severe Trauma.

EMS 145

EMS Outcomes Hospitals Research 145

The Skeptics' Guide to EM

JANUARY 6, 2024

Her research focuses on prehospital care of children with anaphylaxis. […] The post SGEM #425: Are You Ready for This? Her research focuses on prehospital care of children with anaphylaxis. She is nationally known for her work as an EMS researcher and educator. JAMA Netw Open. JAMA Netw Open.

Emergency Department 136

Emergency Department Pediatrics Anaphylaxis Leadership 136

RebelEM

OCTOBER 30, 2023

This could dilute any beneficial effects seen Lack of blinding may bias results (Although mortality is a solid objective primary outcome, bias may still creep in terms of management) Discussion: Authors were looking for an absolute mortality difference of 7% from baseline mortality of 26% with a 90% power. Cryoprecipitate Group: 25.3%

Administration 128

Administration Blood Transfusions Outcomes Hospitals 128

RebelEM

MAY 29, 2023

Most of the research on the use of MB has been in patients with vasoplegia following cardiopulmonary bypass. MB decreases nitric oxide levels by inhibiting inducible nitric oxide synthase (iNOS) and soluble guanylate cyclase (sGC). Through these mechanisms it restores vasoregulation. NaCl over 6hrs once daily x3 doses Placebo: 500mL of 0.9%

Shock 145

Shock Fluid Resuscitation Sepsis Resuscitation 145

Mind The Bleep

JANUARY 18, 2024

Introduction Starting my research journey as a medical student has been an incredible and transformative experience. In this article, I wholeheartedly share my personal journey, and the invaluable lessons I’ve learned along the way, and offer friendly tips to fellow medical students who aspire to delve into the world of research.

Research 52

Research Administration Hospitals Outcomes 52

Sensible Medicine

JULY 29, 2024

The background for cash giveaways stem from the association of low income and worse health outcomes. The primary outcome was positive but there were caveats. Importantly, however, there were no differences in health outcome measures, such as BP, BMI, HbA1c or cholesterol level. More than 70% were first-language Spanish speaking.

Outcomes 118

Outcomes Research Sepsis Emergency Department 118