PulmCCM

JULY 17, 2023

vs 2.5%, a prespecified outcome. Read in Lancet Infectious Diseases Tranexamic acid for severe hemorrhage after trauma (PATCH) An astonishing 2 million people die from bleeding after trauma each year around the world, it is estimated. The findings met the prespecified threshold for non-inferiority margin set at 10%.

Infectious Diseases 52

Infectious Diseases Outcomes Operations Research 52

PulmCCM

JUNE 19, 2023

No drug or combination improved the primary outcome (a composite outcome of hypoxemia, visit to the emergency department, hospitalization, or death). That was in NEJM Aug 18 2022. Metformin also has positive immune-modulatory effects (on cytokine profiles and T-cell immunity).

Infectious Diseases 52

Infectious Diseases Outcomes Hyperthermia / Hypothermia Sepsis 52

PulmCCM

NOVEMBER 6, 2023

This could inform responses in future infectious disease outbreaks; one key seems to be to ensure high titers of neutralizing antibody (at least 1:320 in this study) are present in donor plasma. Thromboelastometry (e.g., The others either improved without it (n=17), deteriorated (n=2) or experienced technical failures (n=8).

Blood Transfusions 98

Blood Transfusions Operations Resuscitation Infectious Diseases 98

PulmCCM

JULY 10, 2023

At 28 days, there were no observed differences in the primary outcome (an odd composite of mortality and emergence of antibiotic resistance), and no difference in survival at 90 days. Read at FDA Paxlovid appears to improve outcomes from Covid-19 infection in younger patients with significant comorbidities , but not in healthy young adults.

Stroke 52

Stroke Sepsis Infectious Diseases Outcomes 52

PulmCCM

FEBRUARY 5, 2024

Fever in the ICU: Guideline Update The Society of Critical Care Medicine (SCCM) and the Infectious Diseases Society of America (IDSA) issued an interim update to their 2008 recommendations for the management of fever in the ICU. PulmCCM is not affiliated with SCCM or IDSA. °C oral measured multiple times).

Best Practices 111

Best Practices Ultrasounds Infectious Diseases Sepsis 111

Taming the SRU

JUNE 12, 2023

Finally, a randomized-control trial found that prophylactic antibiotics for dog bite wounds did not statistically change infection outcomes and was not cost-effective, recommending that prophylactic antibiotics only be used in high-risk wounds [12]. Clinical Infectious Diseases. Stevens DL, Bisno AL, Chambers HF, et al.

Infectious Diseases 98

Infectious Diseases Emergency Department Administration Academics 98

ACEP Now

MARCH 6, 2024

The PATCH-Trauma trial took a critical look at TXA in major trauma in the advanced trauma systems of Australia and found a mixed result: a slightly greater number of patients were still alive six months following TXA administration, but there was no difference in survival with a good functional outcome. percent to 38.3

Research 52

Research Airway Management Stroke Outcomes 52

Sensible Medicine

SEPTEMBER 25, 2023

This has the effect of balancing known and unknown factors, which could affect the primary outcome. The primary outcome of interest was excess burden of multiorgan abnormalities (two or more organs) relative to controls. This study, however, is not an RCT, it is an observational comparison, looking back at results in two groups.

Infectious Diseases 52

Infectious Diseases Hospitals Outcomes Research 52

EM Ottawa

JUNE 10, 2024

Findings: The primary outcome of recurrence of UTI within 30 […] The post Short Oral Antibiotic Therapy for Pediatric Febrile Urinary Tract Infections: A Randomized Trial appeared first on EMOttawa Blog.

Pediatrics 62

Pediatrics Outcomes Infectious Diseases 62

Pediatric EM Morsels

AUGUST 9, 2024

If not treated early, then increased risk of poor outcomes and death. Maternal screening early in pregnancy is the best means to prevent congenital syphilis. Penicillin is 98% effective at preventing congenital syphilis. Hussain, 2023 ] Excellent prognosis if treated early.

Emergency Department 152

Emergency Department Hyperthermia / Hypothermia Seizures Pediatrics 152

Pediatric Education

MAY 12, 2024

These differences can be very important for outcomes of research studies. They can also be important for monitoring of clinical outcomes of treatment in gastroenterological diseases. Stool consistency is only one factor in assessing clinical or research outcomes, including where the stool was produced (i.e.

Pediatrics 40

Pediatrics Infectious Diseases Research Outcomes 40

The Skeptics' Guide to EM

NOVEMBER 28, 2020

However, we do have a firm understanding of the germ theory of disease and masks have been used for over 100 years as an infectious disease strategy. The main outcomes were clinical respiratory illness, influenza-like illness and laboratory-confirmed respiratory virus infection.

Infectious Diseases 52

Infectious Diseases Outcomes Wellness Operations 52

Don't Forget the Bubbles

MARCH 18, 2024

Clinical Infectious Diseases [Internet]. Disease severity of Shiga toxin-producingE. Disease severity of Shiga toxin-producingE. Early Volume Expansion and Outcomes of Hemolytic Uremic Syndrome. Treatment and outcome of Shiga-toxin-associated hemolytic uremic syndrome (HUS). 2016 Jan;6(1):e009933.

Dehydration 59

Dehydration Infectious Diseases Seizures Pediatrics 59

Don't Forget the Bubbles

JANUARY 10, 2024

Some wonder if giving blood to children with a haemoglobin <6g/dl will improve outcomes. Outcomes Primary outcome Mortality at 28 days after randomisation. The authors chose a patient-centred, primary outcome in keeping with their pragmatic design. What were the research questions? The study asked TWO questions: 1.

Blood Transfusions 78

Blood Transfusions Outcomes Research Hospitals 78

EM Curious

JULY 8, 2015

More FOAMed INFECTIOUS DISEASE SMORGASBORD CORE EM PODCAST EPISODE 3 [PODCAST]: Swami sits down to run over some high yield EM topics in the arena of infectious disease, from antibiotic choice in HCAP, to new paradigms in soft tissues infectious. With a bonus brief on disaster management.

Infectious Diseases 52

Infectious Diseases Disaster Management Sepsis Ultrasounds 52

PulmCCM

OCTOBER 30, 2023

Professional Medical Societies Call for Elimination of SEP-1 The Infectious Diseases Society of America (IDSA), along with societies for emergency medicine physicians and hospitalists, are again speaking up about the ongoing policy experiment known as the Centers for Medicare and Medicaid Severe Sepsis/Septic Shock Management Bundle (SEP-1).

Sepsis 52

Sepsis Shock Hospitals Outcomes 52

Pediatric EM Morsels

AUGUST 11, 2023

Infections there become complicated very quickly and the outcomes can be very poor. Inpatient Vs Outpatient Therapy No standard approach… but… here is what I say: “ Always Fear Infections in the Hands, Feet, or Face.” ” Those areas have very important and delicate structures.

Burns 130

Burns Pediatrics EMS Outcomes 130

Dr. No

DECEMBER 19, 2021

Graham Medley , professor of infectious disease modelling at LSHTM, and chief pongo for the time being of SAGE’s modelling group SPI-M, defends the group’s practice of ‘giving the decision makers the information they ask for’ Read that again, and let it sink in.

Infectious Diseases 52

Infectious Diseases Outcomes Dehydration Operations 52

The Skeptics' Guide to EM

MARCH 4, 2018

Currently, the Infectious Diseases Society of America ( IDSA ) guidelines for patients with cellulitis without systemic signs of infection, penetrating trauma, injection drug use, or other evidence of MRSA recommend only prescribing antibiotics against streptococci (1). .

Infectious Diseases 40

Infectious Diseases Documentation/Coding Outcomes Ultrasounds 40

Pediatric Education

OCTOBER 1, 2023

Despite this tremendously positive outcome, there still are continued threats against polio eradication. Learning Point As of 2022 only two countries still have endemic WPV ; those are Afghanistan and Pakistan which in 2019 had a total of 163 recorded cases. Non-polio enteroviruses have emerged which cause acute flaccid paralysis as well.

Infectious Diseases 40

Infectious Diseases Pediatrics Outcomes Wellness 40

Emergency Medicine Education

MARCH 30, 2023

88275 patients reviewed and in hospital mortality and discharge to hospice as a primary outcome measured. JAMA published a retrospective cohort study among septic patients who received vasopressor (norepinephrine) and hydrocortisone to show if adding fludrocortisone was more effective to this regimen compare with only giving hydrocortisone.

Hospice 40

Hospice Outcomes Hospitals Infectious Diseases 40

ALiEM

AUGUST 21, 2023

Risk factors for poor outcomes include immunocompromise (HIV, diabetes, immunosuppression), intravenous drug use, peripheral vascular disease, and polymicrobial infection. Antibiotics should target gram-positive organisms (Staphylococcus, including MRSA, and Streptococcus).

Academics 52

Academics Outcomes Hospitals Wellness 52

Pediatric Education

MAY 26, 2024

The pediatrician said that the child was overall healthy and thriving, with the usual minor infectious disease episodes. The long-term health outcomes for children in childcare are difficult to assess. Multiple Childcare Arrangements and Health Outcomes in Early Childhood. but not for injuries. but not for injuries.

Infectious Diseases 40

Infectious Diseases Pediatrics Outcomes Wellness 40

EMDocs

JANUARY 11, 2024

Systems included neurological, cardiac, pulmonary, hematology, infectious disease, gastrointestinal, endocrine, fluids management, and general critical care. Centers managing patients after CA should collect data and evaluate outcomes of care (95.7%, 22/23).

Seizures 75

Seizures Shock Infectious Diseases CPR 75

Taming the SRU

AUGUST 30, 2023

Spinal Infection: According to the Infectious Disease Society of America’s (IDSA) 2015 guidelines for native vertebral osteomyelitis, CRP and ESR in the setting of protracted back pain have sensitivities ranging from 94 to 100% for ruling out infection and malignancy in these patients. J Arthroplasty. 2019 Feb;34(2S):S187-S195.

Infectious Diseases 81

Infectious Diseases Sepsis Emergency Department Point-of-Care Testing 81

PulmCCM

DECEMBER 11, 2023

Sepsis, infectious disease Managing septic shock with a restrictive-fluids approach (preferentially using vasopressors after a single liter crystalloid bolus) led to similar outcomes as the usual practice of bolusing large volumes of fluids first. Vitamin C did not improve outcomes among patients hospitalized with Covid-19.

Sepsis 94

Sepsis Stroke Shock Infectious Diseases 94

EMDocs

APRIL 27, 2024

However, the bioavailability of antipseudomonal antibiotics has improved outcomes, limiting surgery as a confirmatory diagnostic procedure and as needed for granulation tissue removal. Infectious diseases , 4 (1), 34–39. Infectious diseases, 4(1), 34–39. and Staphylococcus spp. The Lancet. link] Grandis, J.,

EMS 83

EMS Infectious Diseases Radiology Radiology 83

RebelEM

OCTOBER 26, 2023

PMID: 37358858 Clinical Question: In children aged 2 months to 10 years who exhibit clinical improvement after 5 days of antimicrobial therapy for UTIs, is short-course (5 days) oral antimicrobial therapy as effective as standard-course (10 days) therapy in preventing treatment failure and related outcomes? Diagnosed with UTI.

Pediatrics 74

Pediatrics Infectious Diseases Outcomes Research 74

PEMBlog

SEPTEMBER 27, 2023

Reasons to not order a comprehensive respiratory viral panel (i.e.,

Pediatrics 52

Pediatrics Hospitals Emergency Department Infectious Diseases 52

RCEM Learning

APRIL 9, 2024

By following these steps and dedicating sufficient time and effort to your preparation, you can increase your chances of achieving a favourable outcome. Remember, consistent practice and exposure to a variety of SBA questions are key to success in the FRCEM SBA exam. The post FRCEM SBA appeared first on RCEMLearning.

Infectious Diseases 52

Infectious Diseases Airway Management Resuscitation Poisoning 52

Don't Forget the Bubbles

FEBRUARY 28, 2024

Outcomes were: (1) crusting of the lesions; then (2) complete healing of lesions -the end goal of treatment. Was the exposure and outcome accurately measured to minimise bias? There were no objective tests to confirm disease clearance. It was not clear if there was any vested interest in ensuring a certain outcome.

Pediatrics 59

Pediatrics Infectious Diseases Outcomes Research 59

American Medical Compliance

AUGUST 7, 2024

PPEs that OSHA mandates minimize exposure to infectious diseases, ensuring that healthcare workers are adequately protected during patient care. Additionally, OSHA guidelines require the proper handling and disposal of hazardous materials.

Hazardous Materials 91

Hazardous Materials Documentation/Coding Legal Issues Patient Safety 91

Don't Forget the Bubbles

MARCH 4, 2024

This was a secondary outcome embedded in the Travel Fever study – a multi-centre, retrospective diagnostic accuracy study for imported malaria. Safety and efficacy of a nitrous oxide procedural sedation programme in a paediatric emergency department: a decade of outcomes. Emerg Med J. 2024 Jan 22;41(2):76-82. PMID: 38123983.

Hospitals 78

Hospitals Sepsis Fractures Emergency Department 78

RebelEM

FEBRUARY 29, 2024

1, 2 Its occurrence often portends worse outcomes in intubated patients, whose projected hospital course was already tenuous. SECONDARY OUTCOMES At day 28 , ceftriaxone group had (vs placebo): Lower VAP risk (20% vs 36%); hazard ratio 0.62 4, 8 Paper: Dahyot-Fizelier, C.,

CDC 96

CDC Outcomes Radiology Radiology 96

RebelEM

AUGUST 3, 2023

Authors determined they would need to enroll 380 patients (190/group) to achieve a statistical power of 80%, assuming an event rate in the control group of 4% of which neither was achieved however if the control group had a lower prevalence of the outcome (i.e. randomization) as per protocol (i.e.

Anaphylaxis 52

Anaphylaxis Allergic Reactions Outcomes Infectious Diseases 52

Sensible Medicine

JUNE 6, 2023

Two nearly identical trials of the monoclonal drug aducanumab, ENGAGE and EMERGE, had disparate outcomes: ENGAGE showed no benefit and EMERGE showed that the drug slowed decline. This seemed important to consider, and so we looked at whether outcomes in trials of monoclonal antibodies for AD correlated with rates of ARIA.

Outcomes 85

Outcomes Infectious Diseases Research Academics 85

EMDocs

JANUARY 6, 2024

It is difficult to distinguish this from ACS secondary to acute plaque rupture in the ED, and management would be similar with antiplatelet agents, anticoagulation until coronary angiography can be performed to assess for the underlying disease process. 13 Cefepime 2 g or Piperacillin-Tazobactam 4.5 Clin Transplant. 1999;13(3):260-265.

EMS 63

EMS Infectious Diseases Shock Emergency Department 63