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Sepsis Screening Decreases Mortality. Well, not really.

Sensible Medicine

This comment might be one of the reasons I’ve been skeptical of sepsis screening. Sepsis screening, for me, comes in many different flavors -- from EMR alerts based on lab and vital sign data to anyone being able to draw a lactate or call an RRT. Outcomes and patients The primary outcome was 90-day in-hospital mortality.

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2024 Emergency Medicine Research Highlights: Forced Air, Sepsis, and More

ACEP Now

Sepsis Robots or Sepsis Humans The proliferation of sepsis alerts in the ED has reached levels best described as obscene. The common refrain from trained clinicians: We are smarter than any computer or simple scoring system, and we can rapidly and accurately identify sepsis by ourselves, thank you very much. N Engl J Med.

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Sepsis alerts work! Just not in the patients who fire the alerts

PulmCCM

In the past decade, so-called “sepsis alerts” came out of nowhere to become a ubiquitous and resource-intensive component of inpatient medical care. “Sepsis alerts” are automated notifications that flag patients who meet certain criteria compatible with severe infection discernible from the electronic medical record.

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Congestive Heart Failure and Sepsis: A Closer Look at Fluid Management

RebelEM

For those with sepsis, the administration of intravenous fluids (IVF) at the volumes recommended in the Surviving Sepsis Campaign (SSC) requires careful consideration of an individual’s chronic medical conditions and subsequent sensitivity to IVF. What They Did: Researchers performed a systematic review and meta-analysis.

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New "sepsis tests" are here: how well do they work?

PulmCCM

Various new “sepsis tests” have come to market or will soon, claiming to solve the problem of diagnostic imprecision in the early management of suspected sepsis. The lack of a reliable diagnostic test or universally accepted criteria to diagnose sepsis leads to significant challenges in clinical practice and research.

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An Herbal Hope: Is XBJ A Game-Changer in Sepsis Management?

RebelEM

Background: Could Xuebijing (XBJ) catalyze a paradigm shift in sepsis management? XBJ is an herbal compound used in China to manage various inflammatory and infectious processes in recent years, including sepsis. This post evaluates the recent “Efficacy of Xuebijing Injection in Patients With Sepsis (EXIT-SEP)” trial.

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Adjunctive Methylene Blue in Septic Shock?

RebelEM

Background: Sepsis can induce numerous physiologic derangements. Most of the research on the use of MB has been in patients with vasoplegia following cardiopulmonary bypass. At the most severe end, this includes endothelial dysfunction leading to increased vascular permeability, abnormal nitric oxide metabolism, and vasodilation (i.e.

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