PulmCCM

JULY 10, 2023

Continuous meropenem infusion for critically ill patients with sepsis Antibiotics have a time-dependent effect on bacteria; maintaining bacteriocidal concentrations of antibiotics should help subdue infections better than intermittent dosing. Mortality was about 30% in each group, and most patients had hospital-acquired sepsis.

Stroke 52

Stroke Sepsis Infectious Diseases Outcomes 52

EMDocs

JULY 1, 2023

Management of Kawasaki disease includes high-dose aspirin and intravenous immune globulin (IVIG). Patients should be admitted to the hospital and cardiology consulted early in their course. Signs and symptoms of Kawasaki disease include fever for > 5 days, unilateral cervical lymphadenopathy > 1.5 C) for the past week.

EMS 66

EMS Infectious Diseases Pediatrics Hospitals 66

PulmCCM

JUNE 19, 2023

No drug or combination improved the primary outcome (a composite outcome of hypoxemia, visit to the emergency department, hospitalization, or death). Read in Lancet Infectious Diseases Severe hypothyroidism, although rare, may be under-recognized in the ICU and lead to worse outcomes during critical illness, authors of a case series argue.

Infectious Diseases 52

Infectious Diseases Outcomes Hyperthermia / Hypothermia Sepsis 52

Northwestern EM Blog

JUNE 16, 2024

Myocardial Infarction Medication Sinus node dysfunction Infectious Disease Hypothermia Metabolic Abnormalities (hypothyroidism, hyperkalemia, ect.) For example, hypothyroidism, adrenal insufficiency, sepsis, neuromuscular disease, malnutrition, thiamine deficiency, hypoglycemia can all lead to hypothermia [11-13].

Hyperthermia / Hypothermia 52

Hyperthermia / Hypothermia Infectious Diseases Stroke Poisoning 52

ACEP Now

MARCH 6, 2024

Finally, the “EXACT” trial examined whether, in patients with return of spontaneous circulation after an out of hospital cardiac arrest, a peripheral oxygenation target of 90–94 percent conferred a survival benefit, as compared with the typical 98–100 percent. Survival to hospital discharge favored the “standard care” group, 47.9

Research 52

Research Airway Management Stroke Outcomes 52

Don't Forget the Bubbles

JANUARY 10, 2024

Severe anaemia is a common and life-threatening cause of hospital admission in children in sub-Saharan Africa. 8% die in hospital, with a further 12% dying in the six months following discharge. Population 6171 children from three hospitals in Uganda and one in Malawi were assessed for eligibility. Do you believe the results?

Blood Transfusions 78

Blood Transfusions Outcomes Research Hospitals 78

ACEP Now

MAY 4, 2023

Early treatment with broad-spectrum antibiotics is essential to prevent sepsis and preserve testicular function. Dr. Rader works at Ascension Macomb-Oakland Hospital. Dr. Fishman is an associate program director at Ascension Macomb-Oakland Hospital. Fishman is an associate program director at Ascension Macomb-Oakland Hospital.

Urgent Care 52

Urgent Care Ultrasounds Sepsis Emergency Department 52

Don't Forget the Bubbles

MARCH 4, 2024

We have teamed up with the team from the Emergency Department at Bristol Royal Hospital, who have used this as a springboard for their journal club. (It’s The hospital is the Paediatric Major Trauma Centre for the South-West. Reviewed by: John Coveney Article 2: How do we define sepsis in children? doi:10.1001/jama.2024.0179

Hospitals 78

Hospitals Sepsis Fractures Emergency Department 78

Don't Forget the Bubbles

SEPTEMBER 18, 2023

This is true in life-threatening conditions such as sepsis. However, when children do not have features of sepsis, oral antibiotics are equally effective. The take home is that although IV antibiotics are key in sepsis management, oral antibiotics are equally as effective as IV antibiotics for children without critical illness.

Emergency Department 142

Emergency Department Infectious Diseases Pediatrics Sepsis 142

Taming the SRU

AUGUST 30, 2023

In a small study involving 79 hospitalized children, PCT was found to be elevated in bacterial infections, with a decrease after appropriate antibiotic therapy, and decreased in viral infections [24]. Sepsis PCT may have some utility in guiding posttest probability for sepsis when the diagnosis is unclear.

Infectious Diseases 86

Infectious Diseases Sepsis Emergency Department Point-of-Care Testing 86

PulmCCM

DECEMBER 11, 2023

Sepsis, infectious disease Managing septic shock with a restrictive-fluids approach (preferentially using vasopressors after a single liter crystalloid bolus) led to similar outcomes as the usual practice of bolusing large volumes of fluids first. Either approach in severe sepsis with shock seems reasonable.

Sepsis 94

Sepsis Stroke Shock Infectious Diseases 94

Pediatric Education

AUGUST 20, 2023

per 100,000 hospitalizations in 2014. ” In the Belgium study, the most common underlying risk factor was hepatobiliary disease (e.g. Treatment duration again was lengthy for many (up to 154 days) and they had a survival rate of 95.8%. Mortality rate was 0.8%. .” Questions for Further Discussion 1.

Pediatrics 40

Pediatrics Infectious Diseases Wellness Sepsis 40

EMDocs

DECEMBER 18, 2023

Introduction Sepsis and septic shock are life-threatening conditions characterized by severe systemic inflammation and organ dysfunction due to a dysregulated host response to infection. 3,4 Prompt recognition and management of sepsis and septic shock are paramount for the ED clinician.

Sepsis 65

Sepsis Fluid Resuscitation Shock Resuscitation 65

RebelEM

MAY 15, 2024

Antibiotics are effectively the only thing standing between these patients and overwhelming sepsis. Follow your hospital’s protocol (if available). High Risk Patients will need hospitalization and IV antibiotics. Improving the immediate management of neutropenic sepsis in the UK: Lessons from a national audit. Clarke, R.

Infectious Diseases 96

Infectious Diseases Administration Sepsis Anaphylaxis 96