A new, costly cancer drug vs placebo; Cabozantinib in neuroendocrine tumors; How NIH funded trials can fail patients and payers
Sensible Medicine
FEBRUARY 17, 2025
This week in the New England Journal of Medicine , researchers from Harvard, took patients dying of neuroendocrine tumor (this is what Steve Jobs died of) and randomized them to a costly, toxic, branded drug or sugar pill. The trial has issues with control arm, skewed randomization (2:1), drop out and endpoints.
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