Northwestern EM Blog

FEBRUARY 14, 2022

The primary outcome of the study was the response in MAP three hours after the start of angiotensin II infusion. It showed improvement in blood pressure which is a clinically important parameter but not a patient-oriented outcome. However, one limitation of the study was that it was underpowered to demonstrate a mortality difference.

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Shock Resuscitation Fluid Resuscitation Sepsis 52

Don't Forget the Bubbles

MARCH 18, 2024

She receives fluid resuscitation, and you organise some tests to find out why she is so tired. Excessive transfusion can increase the risk of hyperkalaemia and fluid overload. It may worsen HUS, according to some research, though even if platelets are given, the risk of bleeding during a procedure in HUS may not change.

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Dehydration Infectious Diseases Seizures Pediatrics 59

EB Medicine

OCTOBER 1, 2018

Optimal management of septic patients has been a source of intense research, stemming from the landmark study by Rivers in 2001. Also, for research purposes we have to have a common definition, so Sepsis 3 came up with something called the SOFA score. Jeremy, can you give us a little historical context there? So quite a few changes!

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RebelEM

NOVEMBER 30, 2023

This systematic review and meta-analysis attempts to elucidate whether a more conservative fluid resuscitation approach is warranted in volume sensitive sepsis patients, such as those with congestive heart failure (CHF). What They Did: Researchers performed a systematic review and meta-analysis. Am J Emerg Med. 2023;73:34-39.

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Sepsis Fluid Resuscitation Resuscitation Administration 116

EMDocs

DECEMBER 18, 2023

8 Based on multiple randomized controlled trials (RCTs), SSC 2021 guidelines suggest against using procalcitonin as a screening method to guide initiation of antibiotic therapy, as no difference in clinical outcomes was appreciated. 15 Two changes were elucidated in the 2021 SSC guidelines for fluid resuscitation.

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Sepsis Fluid Resuscitation Resuscitation Shock 75

EMDocs

NOVEMBER 20, 2023

High certainty of evidence: further research is unlikely to change the confidence in the estimate of the effect. Moderate certainty of evidence: further research is likely to have an important impact and may change the estimate. Low certainty of evidence: further research is very likely to change the estimate.

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Resuscitation Fluid Resuscitation Hospitals Research 92

Don't Forget the Bubbles

NOVEMBER 18, 2024

Various studies, such as those pooling data from the National Neonatal Research Database, indicate that the incidence of hypotension varies based on neonatal age, with the highest rates observed immediately post-birth and within the first days of life. Effective management of MAS will often result in the stabilization of blood pressure.

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Sepsis Shock Hyperthermia / Hypothermia Administration 59

Don't Forget the Bubbles

JUNE 10, 2024

NEC remains a significant challenge in neonatology, prompting ongoing research and clinical trials to understand its pathogenesis better, improve prevention strategies, and develop more effective treatments. Pediatric Research, 63(2), 117-123. What is the pathophysiology of necrotising enterocolitis? Can we prevent NEC? Hunter, C.J.,

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Pediatrics Sepsis Fluid Resuscitation Outcomes 40

Mind The Bleep

FEBRUARY 27, 2024

There could be any number of reasons for this but some examples are: they have severe D&V and aren’t keeping fluids down, or because they are pre or post-op, or have presented very unwell and need fluid resuscitation. saline), however more research is needed in this area. [4]

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Fluid Resuscitation Hospitals Dehydration Research 96

EMDocs

JANUARY 20, 2024

It was first described in Japan in 1991, where researchers noted a balloon shape to the left atrium resembling a trap used to catch octopuses in Japan. Additional fluids will not improve her condition and may worsen it. Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy. J Neurosurg. 2006;105(2):264-270.

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EMS Fluid Resuscitation Shock EKG/ECG 85

EMDocs

DECEMBER 16, 2023

BMC research notes , 8 , 758. Clinical characteristics and outcome of thyroid storm: a case series and review of neuropsychiatric derangements in thyrotoxicosis. Outcome and risk factors associated with extent of central nervous system injury due to exertional heat stroke. Temps greater than 41.5C link] Kakoki, K., Hakariya, T.,

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Hyperthermia / Hypothermia EMS Stroke Seizures 80

EMDocs

JANUARY 20, 2025

One of the hallmarks of sepsis care, based on the Rivers 2001 17 trial and still recommended by the latest SCCM guidelines is early detection of sepsis and initiation of early resuscitation. link] During the 2017 IV fluid shortage, Patino et al. Inwald et al. Choudhari et al.

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Dehydration Fluid Resuscitation Sepsis Resuscitation 69

Don't Forget the Bubbles

FEBRUARY 17, 2025

Although at a population level, elevated CVP is associated with acute kidney injury (AKI) and other adverse outcomes, the sensitivity and specificity to predict these outcomes for an individual patient is poor. Pudjiadi, Inferior Vena Cava/Abdominal Aorta Ratio as a Guide for Fluid Resuscitation. the kidneys). Raina, R.,

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Pediatrics Ultrasounds Shock Resuscitation 78

Taming the SRU

FEBRUARY 3, 2025

In recent research, it has been discovered that as high as 42% of adult cancer patients and 70% of pediatric cancer patients suffer from laboratory changes associated with TLS, but have no associated clinical symptoms (9). InHospital Outcomes of Tumor Lysis Syndrome: A PopulationBased Study Using the National Inpatient Sample.

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Fluid Resuscitation Seizures Dehydration Emergency Department 55