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Sepsis Screening Decreases Mortality. Well, not really.

Sensible Medicine

If sepsis screening was shown to be beneficial in one hospital, would it be beneficial in another, with an entirely different set of caregivers? Article Background With all that as background, I was excited when I saw the article Electronic Sepsis Screening Among Patients Admitted to Hospital Wards in JAMA.

Sepsis 98
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But Can You Just PO?

Taming the SRU

Fluid management in the Emergency Department (ED) is crucial in the adequate resuscitation of the acutely ill and decompensating patient. Patients present to the ED with hypovolemia secondary to a plethora of causessome requiring IV fluid resuscitation and others requiring none. AtherlyJohn et al.

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ToxCard: Iron

EMDocs

Aggressive fluid resuscitation as patients may be severely hypovolemic from GI symptoms. Case Follow-up: The patient received a fluid resuscitation with 20 mL/kg bolus of normal saline. Iron Ingestion: an Evidence-Based Consensus Guideline for Out-of-Hospital Management. Antiemetics as needed. 2 L/hr in adults.

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Congestive Heart Failure and Sepsis: A Closer Look at Fluid Management

RebelEM

This systematic review and meta-analysis attempts to elucidate whether a more conservative fluid resuscitation approach is warranted in volume sensitive sepsis patients, such as those with congestive heart failure (CHF). Outcomes: Primary Outcome: In-hospital mortality. Am J Emerg Med. 2023;73:34-39. 2.89, p = 0.01.

Sepsis 122
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Adjunctive Methylene Blue in Septic Shock?

RebelEM

Judicious fluid resuscitation is indicated in patients with signs of hypo perfusion but is often inadequate necessitating the administration of vasoactive medications. It also reduced length of stay in ICU and hospital without adverse effects. septic shock). NaCl over 6hrs once daily x3 doses Placebo: 500mL of 0.9% 95% CI 15.4

Shock 145
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Trauma Resuscitation Updates

RebelEM

Lancet 2010 [10] >20,000 adult trauma patients with SBP <90mmHg Patients randomized to TXA 1g over 10 min + 1g IV over 8hrs vs Placebo given within 8hrs of injury In-hospital mortality by 28d reduced (14.5% NEJM 1994. [2] NEJM 1994. [2]

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Major burns in adults: a practice review

Emergency Medicine Journal

Most burn injuries can be treated in local hospitals but 6.5% The initial ED assessment, resuscitation and critical care of the severely burned patient present significant challenges and require a multidisciplinary approach. There are approximately 180 000 deaths per year from thermal burn injury worldwide.

Burns 98