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ToxCard: Second Generation Antipsychotic Overdose

EMDocs

of exposures reported to poison control centers in 2021 were related to antipsychotics or sedative-hypnotics with the majority of those exposures occurring in patients 20 years of age or older. 1 Seizures may occur due to lowered seizure threshold. 6 Seizures have been observed and are dose-dependent.

Poisoning 108
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Seizure in a 30 something

Dr. Smith's ECG Blog

Her husband called EMS when the patient experienced new onset seizures accompanied by micturition. The ECG below was recorded by EMS. ECG #1 Interpretation: ECG #1 shows sinus rhythm at a heart rate of 77 bpm. At first glance, the ECG does not look too abnormal. All patients with seizures needs an ECG.

Seizures 114
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REBEL Core Cast 109.0 – Na Channel Blocker Poisoning

RebelEM

Take Home Points: In the context of poisoning, a “wide QRS” is anything greater than 100 milliseconds. Authors evaluated the relationship between QRS duration and negative clinical events in patients with confirmed tricyclic anti-depressant (TCA) poisoning. Treatment is guided by administration of sodium-bicarbonate. Boehnert 1985 ).

Poisoning 100
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ToxCard: Benzonatate

EMDocs

Her electrocardiogram (ECG) showed atrial fibrillation which was cardioverted to sinus rhythm. 8) Over the next 24 years, numerous peer reviewed publications on benzonatate poisoning appeared in the medical literature. (3, Upon ED arrival, she had a heart rate (HR) of 160 and blood pressure (BP) of 80s/40s.

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ToxCard: Local Anesthetic Systemic Toxicity

EMDocs

She reportedly received a landmark guided peripheral nerve block with bupivacaine and shortly thereafter developed generalized seizures. 1,5] CNS symptoms include: Seizure, coma, altered mental status. [1] 1-3,5,7,9] All patients developing symptoms of LAST should be placed on a continuous cardiac monitor and have an ECG performed. [2]

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Chemical Burns

Mind The Bleep

Circulation Assess heart rate, blood pressure, peripheral and central CRT, pulses and 3 lead ECG. National Poisons Information Service (0344 892 0111) and TOXBASE have useful information on special chemicals and are accessible 24/7. Administer high-flow oxygen if indicated and consider arterial blood gas ( ABG ).

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Grand Rounds Recap 4.19.23

Taming the SRU

Subsequent exposure results in a T-cell mediated response (Type IV hypersensitivity reaction) Plants: Toxicodendron species (poison ivy, poison oak, poison sumac) Also present in foods, including pistachio, cashew, and mango.