Sat.Nov 23, 2024 - Fri.Nov 29, 2024

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The NIH Needs Reform: Here are 10 Sensible Suggestions

Sensible Medicine

It is my pleasure to introduce this article by Joseph Marine, MD. Mr. Marine has 10 sensible suggestions for reform at the NIH. I love them all, but particularly #3, 6, and 8, which I have railed about for years. Vinay Prasad, MD MPH The NIH needs reform The recent news that Dr. Jayanta Bhattacharya is being considered for the post of Director of the National Institutes of Health (NIH) was received with enthusiasm by many of us who opposed the US pandemic response.

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ECG Blog #457 — Is Anything Conducting?

Ken Grauer, MD

I was sent the ECG shown in Figure-1 — told only that that it was from an acutely ill patient on a ventilator, who was being evaluated for bradycardia. His providers thought this rhythm was complete AV block. QUESTIONS: How would you interpret the ECG in Figure-1 ? Is the rhythm complete AV block? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ).

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Ultrasound Guided Peripheral IVs

EM Ottawa

What do you do when expert nurses tell you they can’t obtain IV access? Do you spend 20 minutes performing an invasive central line? Does your resident finally get two IO EPAs? Or do you save the day with a slick, ultrasound guided IV? Obtaining peripheral ultrasound guided IV access is not only a core […] The post Ultrasound Guided Peripheral IVs appeared first on EMOttawa Blog.

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What makes a T-wave Hyperacute? And: 30 Examples of Hyperacute T-waves, 10 in each of 3 myocardial territories.

Dr. Smith's ECG Blog

Pendell and I and the geniuses at Powerful Medical (Producers of the PMCardio Queen of Hearts OMI AI app ) are working on an objective, mathematical definition of hyperacute T-waves , based on real OMI outcomes and hyperacute T-wave annotation that has excellent interrater agreement (between me and Pendell), and it will end up being a logistic regression using these 3 variables: 1) area under the curve (AUC) relative to the QRS size 2) increased symmetry , as defined by time from T-wave onset to

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Podcast – Bad Behaviour in Teams with Liz Crowe at Tactical Trauma 2024

St. Emlyn

St.Emlyn's - Emergency Medicine #FOAMed In this podcast, Liz Crowe discusses the effect bad behaviour has on teams and ultimately patient safety. The post Podcast – Bad Behaviour in Teams with Liz Crowe at Tactical Trauma 2024 appeared first on St.Emlyn's.

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Marty Makary is up for FDA commissioner

Sensible Medicine

Marty Makary, an editorial board member of Sensible Medicine, is up for FDA commissioner. In honor of that, we reprint one of his essays. Elsewhere I have a short piece on how the media coverage of him has been biased, and why I support his nomination. In the piece below Marty was correct that there is no data to support year over year COVID boosters, and I, like most Americans, don’t get them.

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PulmCrit: How to quickly create a useful professional account in BlueSky

EMCrit

I discussed the reasons for migrating to BlueSky here. I've received positive feedback from several FOAMed expats who migrated to Bluesky and enjoy it there. I've also received some questions about getting started on BlueSky, so here is a brief guide to moving into MedSky. [1] Set up your account & profile This is essentially […] EMCrit Project by Josh Farkas.

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GLP-1A toxicity: What do emergency clinicians need to know about drugs like Ozempic® and Wegovy®?

St. Emlyn

St.Emlyn's - Emergency Medicine #FOAMed GLP-1A toxicity: What do emergency clinicians need to know about drugs like Ozempic® and Wegovy®? #FOAMed @stemlyns Greg Yates takes through a paper reporting overdoses in US practice. The post GLP-1A toxicity: What do emergency clinicians need to know about drugs like Ozempic® and Wegovy®? appeared first on St.Emlyn's.

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The Value of Reanalysis of a Clinical Trial

Sensible Medicine

When a clinical trial is published, people are relieved. The researchers did the work, analyzed the data, published the report and surely feel a sense of completion. Clinicians are relieved because we have more evidence to use in patient care. The question is how certain we should be about the trial’s result. In April, I covered the work of Dena Zeraatker , from McMaster University, who elegantly showed that there were thousands of ways to analyze data from observational studies.

Research 105
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ZDoggMD on RFK Jr.’s Rise: “I’m Talking About Like These Science Based Medicine Guys”

Science Based Medicine

Dr. Zubin Damania praised and promoted RFK Jr.-loving doctors. We criticized these doctors and corrected their factual errors. See the difference? The post ZDoggMD on RFK Jr.’s Rise: “I’m Talking About Like These Science Based Medicine Guys” first appeared on Science-Based Medicine.

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Advancing Diabetes Management with CGM Training 

American Medical Compliance

Continuous Glucose Monitoring (CGM) technology is transforming the approach to diabetes care for healthcare providers, including endocrinologists, diabetes educators, and nurses, as well as for the patients they support. Unlike traditional methods that rely on periodic fingerstick tests, CGM offers real-time insights into glucose levels, trends, and fluctuations, empowering proactive management and improving patient outcomes.

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How should we assess febrile infants? Results from the FIDO study

Don't Forget the Bubbles

Imagine this – a six-week-old infant with a fever of 38.3⁰C presents to your emergency department. They look well and, apart from fever, have no other symptoms. There are no sick contacts at home. Although they look well, you don’t want to miss a serious diagnosis, so what do you do? You’ve so many questions. Which of the many febrile infant clinical decision tools should you use?

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Friday Reflection 46: The Best of Days

Sensible Medicine

PR is an 82-year-old woman who is brought to the emergency room after “an episode.” During her first 12 hours in the hospital, she saw an emergency medicine resident and attending, a neurology resident and attending, and finally an internal medicine intern and resident who were covering the “night-float” shift. By the time these last two met her, she was pretty well wiped out, so the case they presented to us, her admitting team, was mostly cobbled together from the other

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Any Doctor Who Enabled RFK Jr. In Any Way Is Anti-Vaccine No Matter How They Describe Themselves

Science Based Medicine

If you associate yourself with Sensible Medicine, you are anti-vaccine no matter how you describe yourself. The post Any Doctor Who Enabled RFK Jr. In Any Way Is Anti-Vaccine No Matter How They Describe Themselves first appeared on Science-Based Medicine.

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WOMAN-2: What Does the Robot Say?

EM Literature of Note

Following on the success of Toy Story 2, Inside Out 2, and Avatar 2, we have WOMAN-2, yet another trial featuring emergency medicine’s third-favorite medication: tranexamic acid. However, where those sequels succeeded, WOMAN-2 is more like Miss Congeniality 2 – the one we’re not going to talk about again. But, don’t take it from me – take it from the ChatGPT Agent I created!

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Recent MI at another facility. Now back in the ER with chest pain

Dr. Smith's ECG Blog

Written by Willy Frick A young woman with a history of paroxysmal nocturnal hemoglobinuria presented with acute substernal chest pain. Five days prior, she had a similar presentation to a different hospital. She underwent coronary angiography which showed thrombotic occlusion of an RPL branch s/p aspiration thrombectomy. The report describes heavy plaque in the proximal RCA by IVUS, but no lesions in the previously occluded RPL branch and no stent was deployed.

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The Health Equity Agenda is a Bad Prescription

Sensible Medicine

The disparities in health outcomes in the US, most notably between black and white, is appalling. It is an effect of our country’s original sin, compounded by hundreds of years of racism. Whether you examine specific health issues -- COVID , gun violence , cardiovascular death – or overall mortality , the differences are repugnant, embarrassing, and heart breaking.

Research 107
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The First10EM monthly wrap-up for autumn 2024

First 10 EM

The First10EM monthly wrap up is a place for me to share updates about the website, about my academic life, and also interesting content, such as books, podcasts, and other FOAMed, that I have encountered in the prior month (or now quarter). Obviously the format means the focus is mostly on content I have found, […] The post The First10EM monthly wrap-up for autumn 2024 appeared first on First10EM.

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Methanol poisoning

Don't Forget the Bubbles

It’s a busy day in the paediatric ED. A worried parent rushes in carrying a toddler who’s just had a gulp from an unlabelled bottle in the garage. The child looks unsettled but otherwise fine—for now. “It was just a bit of the stuff we use for cleaning the car windscreen,” the parent says. You smell the faint odour of alcohol on the child’s breath A quick mental note: methanol poisoning?

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SGEM#461: If You’re Appy and You Know It…Do You Need a Clinical Prediction Score?

The Skeptics' Guide to EM

Date: November 13, 2024 Reference: Lee WH, et al. Study of Pediatric Appendicitis Scores and Management Strategies: A Prospective Observational Feasibility Study. Academic Emergency Medicine. Dec 2024 Guest Skeptic: Dr. Dennis Ren is a pediatric emergency medicine physician at Children’s National Hospital in Washington, DC. He’s also the host of SGEMPeds.

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Journal Feed Weekly Wrap-Up

EMDocs

We always work hard, but we may not have time to read through a bunch of journals. It’s time to learn smarter. Originally published at JournalFeed , a site that provides daily or weekly literature updates. Follow Dr. Clay Smith at @spoonfedEM , and sign up for email updates here. #1: Could Paralyzing Before Sedatives Increase First Pass Success? Spoon Feed This study utilized Bayesian analysis and found that when paralytic medications were administered before sedatives during ED intubation, the

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241. Great Stuffing Choke: Peds Airway Obstruction

Board Bombs

You've survived Thanksgiving, now survive managing a pediatric airway obstruction by foreign body. This case will make you wish your in-laws came back to visit for Christmas. Want to experience the greatest in board studying? Check out our interactive question bank podcast- the FIRST of its kind at here. Cite this podcast as: Briggs, Blake; Husain, Iltifat. 241.

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How should we assess febrile infants with a positive viral respiratory test? – results from the FIDO study

Don't Forget the Bubbles

A 7-week-old baby presents to the Emergency Department (ED) with a one-day history of coryza and cough. Parents have recorded a temperature of 38°C at home. In triage, she is noted to be alert and feeding well. Her initial observations show a temperature of 38.2°C, HR 152 bpm, RR 45/min, and oxygen saturation 97% in room air. You perform a viral swab test at ED which comes back positive for SARS-CoV-2.

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Roc vs. Succ | Pericarditis Reviewed

JournalFeed

The JournalFeed podcast for the week of Nov 25-29, 2024. These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member. Monday Spoon Feed : This secondary analysis of 2 RCTs found no significant difference between rocuronium or succinylcholine on first attempt success or severe complications in critically ill patients undergoing endotracheal intubation.

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Chest (or abdominal?) pain and ECG artifact.

Dr. Smith's ECG Blog

An elderly woman presented with one day of chest and right arm pain, and also abdominal pain. There was associated tingling and numbness in the right hand and generalized weakness, worse on the right side. A triage ECG was recorded: Smith : there is widespread artifact, except in lead III. Since lead III is not artifactual, one can deduce that t he artifact is caused by movement of the right arm electrode, so that electrode should be moved and the ECG re-recorded.

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Threading the Needle: Bougie-First Intubation

RebelEM

Background: In 2018, the BEAM Trial, a small single-center randomized clinical trial, conducted in the emergency department at Hennepin County Medical Center, demonstrated that bougie use significantly increased the first-attempt intubation success rate compared to the endotracheal tube with stylet (98% vs 87% (absolute difference, 11% [95% CI, 7% to 14%]). 1 Conversely, the 2021 BOUGIE trial—a larger, multicenter randomized clinical trial conducted by the same investigators—found no significant

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Thanks to all our subscribers

Sensible Medicine

A few years ago, meeting on zoom, Vinay had an improbable idea: What if we worked together on a single substack. The idea was Sensible Medicine — a place to debate ideas in biomedicine, to host debates, to tell stories from the trenches, to dissect articles. What would a substack look like that featured not just one voice, or two voices, but a range of voices in medicine.

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Tibeten women with higher O2 have more children

The Evolution & Medicine Review

Ongoing selection for adaptation to high altitude Ye, S., Sun, J., Craig, S. R., Di Rienzo, A., Witonsky, D., Yu, J. J., Moya, E. A., Simonson, T. S., Powell, F. L., Basnyat, B., Strohl, K. P., Hoit, B. D., & Beall, C. M. (2024).

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Lab case 453

EMergucate

72 year-year-old man with history of type II DM and has a single kidney. Presented with 2 weeks of diarrhoea. He has been in bed for 2 weeks. Unresponsive. Last proper meal was 2 weeks ago.

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Are you compliant? New California law requires AEDs in high-occupancy buildings

AED Leader

California is leading the way in public safety with a new law that could save countless lives during cardiac emergencies. Effective January 1, 2017, the state’s Health and Safety Code 19300 mandates that certain high-occupancy buildings must install Automated External Defibrillators (AEDs). This legislation reflects a growing recognition of how crucial AEDs are in improving survival rates for sudden cardiac arrest (SCA).

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Medical Music Mondays: Hip Pain Blues

PEMBlog

The Kocher criteria can help you rule out a septic hip. Transient Synovitis is a much better diagnosis. It used to be called Toxic Synovitis, but that name was too scary so it got changed. Lyrics In a kid with hip pain I’ve got to explain The Kocher criteria And using your brain Cannot bear weight A fever complaint White count 12K ESR 40 today I’ve they’ve got all four The hips septic for sure But if they have none Then show them the door Note: CRP of >2.5 can replace ESR>40, but it was

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240. A Salty Solution: SCARY Hyponatremia

Board Bombs

We have a short attention span in the ED….so it’s okay to defer hyponatremia to the real nerds (psst internal medicine). But there are a few indications when we need to jump into action to save the day. Want to experience the greatest in board studying? Check out our interactive question bank podcast- the FIRST of its kind at here. Cite this podcast as: Briggs, Blake. 240.

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CHEST Transfusion Thresholds | Paralytic or Sedative First?

JournalFeed

The JournalFeed podcast for the week of Nov 18-22, 2024. These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member. Monday Spoon Feed : Most of the time, targeting a hemoglobin threshold of 7 – 8 g/dL in critically-ill patients is recommended, with acute coronary syndrome as the exception to the rule.

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Imaging Case of the Week 610 Answer

EMergucate

The supine chest x-ray shows left sided deep sulcus sign (lucency diving deep into left upper quadrant) indicative of a … Continue reading →

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5 Minute Sono – Sonosite LX Machine Basics

Core Ultrasound

In this video tutorial, we provide a detailed guide to operating the Sonosite LX ultrasound machine. Designed for both beginners and those familiar with ultrasound technology, this demonstration will walk you through the essential features and functions of this device. You’ll learn how to power it on, optimize image quality, navigate the user interface, save and review images, and utilize its advanced settings to improve your workflow. > The post 5 Minute Sono – Sonosite LX Machine Basics

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Derivation of the Falls Decision Rule to exclude intracranial bleeding without head CT in older adults who have fallen

EM Ottawa

Methodology: 3.5/5 Usefulness: 3.5/5 CMAJ. 2023 Dec 3;195(47):E1614-E1621. de Wit K, et al. doi: 10.1503/cmaj.230634. Question and Methods: The Falls Decision Rule was derived to identify older adults with fall who do not require CT to rule out intracranial bleeding, using logistic regression. Findings: The rule demonstrated 98.6% sensitivity and 20.3% specificity for detecting significant […] The post Derivation of the Falls Decision Rule to exclude intracranial bleeding without head CT

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Thank You

Stop and Think

Just a short note to say thank you to those who follow this Substack. I am grateful to have readers. It’s Thanksgiving here and it is nice that my brain gets a holiday. Peace be with you all. JMM Stop and Think is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

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