January, 2025

article thumbnail

Direct Oral Anticoagulant (DOAC) Reversal: Part 3

The Trauma Pro

In my last two posts, I reviewed some older papers on the efficacy of Andexxa (andexanet alfa) for the reversal of Factor Xa inhibitor anticoagulants. Those results were not very impressive, especially considering the high cost of this drug. In 2021, an article was published (reference 1) that performed a systematic review of the literature from 2017 to 2020.

article thumbnail

The willful blindness of RFK Jr’s supporters

Science Based Medicine

Shrug, move on and never admit you were wrong The post The willful blindness of RFK Jrs supporters first appeared on Science-Based Medicine.

145
145
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Is RFK Jr to blame for the Samoa measles outbreak? An empirical analysis of published scholarly papers and news stories

Sensible Medicine

Just out, we have a new paper on a provocative question. What factors were blamed for the 2019 Samoa measles outbreak in the peer reviewed literature and news coverage? At the time, and now 5 years later? Subscribe now First, we assembled every single peer reviewed article and mainstream media news story on the Samoa measles outbreak. 163 studies met our criteria.

Academics 145
article thumbnail

Torsade in a patient with left bundle branch block: is there a long QT? (And: Left Bundle Pacing).

Dr. Smith's ECG Blog

By Smith with comments from our electrophysiologist, Rehan Karim. (And of course Ken's comments at the bottom) An elderly obese woman with cardiomyopathy, Left bundle branch block, and chronic hypercapnea presented hypoxic with altered mental status. She was intubated. Bedside cardiac ultrasound showed moderately decreased LV function. CT of the chest showed no pulmonary embolism but bibasilar infiltrates.

EKG/ECG 118
article thumbnail

The Death of Critical Thinking in Emergency Medicine

ACEP Now

In recent years, emergency medicine, once the bastion of quick decision making, clinical acumen, and patient-centered care, has been quietly succumbing to a different forcethe slow but steady erosion of critical thinking. The culprit is the increasing reliance on protocolization and the diminishing autonomy of emergency physicians. This shift, intended to standardize care and mitigate error, is paradoxically undermining the very heart of medicinethe doctors ability to think critically, adapt to

article thumbnail

These are the ‘Roids you are looking for – Steroids in the ED

EM Ottawa

In the acute care setting, steroids have various usages and indications, but their usage can often be nuanced. From adrenal crises to septic shock, severe community-acquired pneumonia, and even acute pharyngitis, steroids play a pivotal role in managing a variety of conditions encountered in the Emergency Department (ED). However, their use is far from straightforwardbalancing […] The post These are the ‘Roids you are looking for – Steroids in the ED appeared first on EMOttawa

Shock 113
article thumbnail

Emergency Evidence Updates – December 2024

The Bottom Line

Whats new in the Critical Care literature monthly updates

109
109

More Trending

article thumbnail

Seed Oils: Real Harm or Just Another Food Fear Fad?

Sensible Medicine

Two health obsessions that I’ve never really understood are the supposed benefits of vitamin D (for every imaginable ill) and harm of seed oils. Dr. Bobby Dubois thinks a lot about the evidence behind health recommendations on his podcast. His research has led him to a pretty clear opinion about the role of seed oils in health and disease. Attentive Sensible Medicine readers will note that his take is a bit different from that expressed in a recent post.

Wellness 108
article thumbnail

Online QT calculator for wide QRS (LBBB, RBBB, etc.)

Dr. Smith's ECG Blog

(This was created by Arron Pearce ( [link] ) Online QT calculator for wide QRS (LBBB, RBBB, etc.

113
113
article thumbnail

Post-Tonsillectomy Hemorrhage: A Three-Pronged Approach

ACEP Now

Its 4 a.m., and youre three hours from the nearest tertiary care center. A young woman, 13 days post-tonsillectomy, comes into your rural emergency department (ED) coughing up blood. On exam, you see bright red blood trickling down her left tonsillar fossa. Her vital signs are normal, except for a heart rate of 115 bpm. Its going to take time to get her to a tertiary center.

article thumbnail

Is it time to reframe resuscitation in trauma?

Emergency Medicine Journal

Trauma remains a significant cause of mortality and morbidity. Non-compressible torso haemorrhage is one of the key drives of these mortality data. Our contemporary management has focused on damage control resuscitation, with a focus on haemorrhage control, haemostatic resuscitation and permissive hypotension. The evidence for permissive hypotension lacks the robustness as other treatments, such as tranexamic acid.

article thumbnail

Critical Care Evidence Updates – December 2024

The Bottom Line

Whats new in the Critical Care literature monthly updates

109
109
article thumbnail

Defenders of the Great Barrington Declaration Neither Know Nor Care What it Proposed. The Deliberate Erasure of the We Want Them Infected Movement Has Succeeded.

Science Based Medicine

Defenders of the GBD won't tell you what it actually said. I will. The post Defenders of the Great Barrington Declaration Neither Know Nor Care What it Proposed. The Deliberate Erasure of the We Want Them Infected Movement Has Succeeded. first appeared on Science-Based Medicine.

138
138
article thumbnail

Robert F. Kennedy Jr. and the Treatment of Drug Addiction

Sensible Medicine

If Robert F. Kennedy Jr. is confirmed as the next secretary of the Department of Health and Human Services, and if he carries out even part of his agenda , he will be a consequential -- and controversial -- cabinet secretary. I am concerned about some of his stances , including his record of objecting to vaccines, but in other areas, starting with addiction, his vision and values could transform lives.

article thumbnail

EM@3AM: Stercoral Colitis

EMDocs

Author: Christopher Blanton, MD, MBA (EM Resident, UTSW / Dallas, TX); Joslin Gilley-Avramis, MD (EM Attending Physician, UTSW / Parkland Memorial Hospital) // Reviewed by: Sophia Grgens, MD (EM Physician, BIDMC, MA); Cassandra Mackey, MD (Assistant Professor of Emergency Medicine, UMass Chan Medical School); Brit Long, MD (@long_brit) Welcome to EM@3AM, an emDOCs series designed to foster your working knowledge by providing an expedited review of clinical basics.

EMS 94
article thumbnail

Pre-Hospital Emergency Anaesthesia (PHEA) vs. Emergency Department RSI: A Comparative Study on Trauma Care Timelines and Outcomes

St. Emlyn

St.Emlyn's - Emergency Medicine #FOAMed How does pre-hospital emergency anaesthesia (PHEA) delivered by Helicopter Emergency Medical Services (HEMS) impacts trauma care timelines compared to emergency department RSI (EDRSI). This retrospective study explores time efficiency, injury severity, and patient outcomes, highlighting the role of HEMS in delivering critical care to severely injured patients in remote locations.

article thumbnail

Journal update monthly top five

Emergency Medicine Journal

This month’s update is by the Emergency Department of the University Hospital of Heraklion, Crete, Greece. We used a multimodal search strategy, drawing on free open-access medical education resources and literature searches. We identified the five most interesting and relevant papers (decided by consensus) and highlighted each paper’s main findings, key limitations and clinical bottom line.

article thumbnail

The EM Expert Mindset – A Female Perspective

Emergency Medicine Cases

Dr. Patricia Lee is an EM physician in Calgary, Alberta and an Assistant Professor at the University of Calgary in the Department of Emergency Medicine. She reached out to me after listening to Episode 200 How EM Experts Think Part 1 as a longtime supporter of EM Cases, to highlight the importance of recognizing challenges that female-identifying EM physicians may face before, during and after ED shifts.

EMS 108
article thumbnail

The Semmelweis gambit: A red flag for defending bad science and quackery

Science Based Medicine

A proponent of the Great Barrington Declaration is comparing rejection of its "natural herd immunity" approach to the pandemic to the rejection of Ignaz Semmelweis and his findings. It's a deceptive comparison beloved of all manner of scientific cranks. The post The Semmelweis gambit: A red flag for defending bad science and quackery first appeared on Science-Based Medicine.

136
136
article thumbnail

Zombie Healthcare Masking Policies Return to Maryland

Sensible Medicine

A limited mask mandate is returning to my state this week. In 2023, the Maryland Department of Health (DOH) adopted a standard for return to universal masking in healthcare facilities when hospitalizations with respiratory viruses (covid, influenza, or RSV) reach a level of 10 cases per 100,000 population. Maryland has a population of 6.3 million and about 10,000 licensed hospital beds, so that works out to about 6% of hospital beds.

CDC 99
article thumbnail

EM Innovation Collaborative - An interview with Nicholas Stark, MD, MBA & Zaid Altawil, MD

EB Medicine

In this episode, Sam Ashoo, MD interviews Nicholas Stark, MD, MBA & Zaid Altawil, MD about the Emergency Medicine Innovation Collaborative 1. Discussion on EMIC - Overview of the collaborative - Background and formation during the pandemic in late 2021 2. Growth of EMIC - Expansion from three members to over 500 - Focus areas: Education, mentorship, opportunity 3.

EMS 82
article thumbnail

Neuroimaging Cases 007

Life in the Fast Lane

Michael Gibbs MD Neuroimaging Cases 007 Nail gun injury. First in our Neuroimaging case study series with Teresa Crow , Troy Carnwath, Scott DiMeo, L.

article thumbnail

Podcast – Likelihood Ratios: Critical Appraisal Nugget 12

St. Emlyn

St.Emlyn's - Emergency Medicine #FOAMed Mastering likelihood ratios can transform your diagnostic skills. In this podcast with Rick and Greg, discover how likelihood ratios can enhance decision-making and improve patient care. The post Podcast – Likelihood Ratios: Critical Appraisal Nugget 12 appeared first on St.Emlyn's.

Research 109
article thumbnail

EM Quick Hits 62 Optimizing RSI Medication Timing, ED Boarding of Older Patients, Prolonged Tourniquet Use, Rural Peer Support Programs, ECG Reciprocal Changes, Nutrition Tips for Shift Workers

Emergency Medicine Cases

On this month's EM Quick Hits podcast: Anand Swaminathan on optimizing RSI medication timing, Brittany Ellison ED boarding challenges in older patients and solutions to ED crowding and flow, Dave Jeromeon managing prolonged tourniquet application, Nour Khatib and Phil Gillick on a rural peer support case, Jesse McLaren on ECG reciprocal changes in acute coronary occlusion, and Melody Ngon practical nutrition tips for shift workers.

EMS 92
article thumbnail

Dr. Jay Bhattacharya Was Nice to Someone During a Debate. That Doesn’t Erase the Consequences of His Misinformation.

Science Based Medicine

This is what it looks like when doctors treat the pandemic as an intellectual parlor game. The post Dr. Jay Bhattacharya Was Nice to Someone During a Debate. That Doesnt Erase the Consequences of His Misinformation. first appeared on Science-Based Medicine.

125
125
article thumbnail

Pulse oximeters overestimate O2 saturations in darker-skin patients; FDA acts (again)

PulmCCM

Pulse oximeters for healthcare and consumer use are calibrated on patients with lighter skin. Manufacturers have recognized the devices’ suboptimal performance in darker-skinned patients for decades, but they have faced no serious regulatory or legal pressure to act. In 2013, FDA issued a suggestion that manufacturers test devices on patients “with a range of skin pigmentations.” But the standard was lax: only two darkly pigmented subjects, or 15% of the total pool were needed.

article thumbnail

EMCrit 392 – All Things Defibrillation with Sheldon Cheskes

EMCrit

Nitty Gritty of All Things Defibrillation EMCrit Project by Scott Weingart, MD FCCM.

90
article thumbnail

BALANCE – 7 vs 14 days of antibiotics

The Bottom Line

Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections BALANCE Investigators. NEJM 2024; DOI: 10.1056/NEJMoa2404991 Clinical Question In hospitalised patients with bloodstream infections (BSI), is antibiotic treatment for 7 days, compared to treatment for 14 days, non-inferior with respect to mortality at 90 days?

95
article thumbnail

JUNCTIONAL ESCAPE RHYTM

ECG Guru

In this 12-lead ECG there is a bradycardic rhythm, which is regular, heart rate about 45 bpm. The QRS complexes are narow. What is this rhythm called? There are no P waves present, and no flutter or fibrillation waves can be seen. There are 2 possibilities: 1. There is a sinus arrest with a junctional escape rhythm. The junctional rhythm either cannot conduct retrograde to the atria (therefore no inverted retrograde P wave can be seen) or the retrograde P wave is hidden in the QRS complex (atria

EKG/ECG 93
article thumbnail

EM@3AM: Leukopenia

EMDocs

Authors: Michael Sperandeo, MD (Assistant Professor, Dept of Emergency Medicine, Long Island Jewish Medical Center, Associate Program Director EMSL Medical Simulation Fellowship, Zucker School of Medicine at Hofstra/Northwell); Sophia Grgens, MD (EM Physician, BIDMC, MA) // Reviewed by: Cassandra Mackey, MD (Assistant Professor of Emergency Medicine, UMass Chan Medical School); Brit Long, MD (@long_brit); Alex Koyfman, MD (@EMHighAK) Welcome to EM@3AM, an emDOCs series designed to foster your wo

EMS 86
article thumbnail

A Challenge For Dr. Edward Livingston: Defend the Great Barrington Declaration Without Censoring the Great Barrington Declaration

Science Based Medicine

In 2020, the GBD was all about herd immunity via natural immunity. Today, its defenders censor that. The post A Challenge For Dr. Edward Livingston: Defend the Great Barrington Declaration Without Censoring the Great Barrington Declaration first appeared on Science-Based Medicine.

117
117
article thumbnail

Alkali Exposure

EB Medicine

In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the January 2025 Emergency Medicine Practice article, Alkali Exposure: An Evidence-Based Approach to Diagnosis and Treatment Patient Demographics and Case Scenarios: Types of patients prone to alkali exposure Causes and scenarios leading to alkali exposure (e.g., accidental, intentional, social media challenges) Poison control reports and statistics Types and Effects of Exposure: Different types of exposure: ingestion, ocular, dermal Eff

article thumbnail

EMCrit 393 – CV-EMCrit – Inotrope Basics Part 1

EMCrit

The basics of inotropes - part 1 EMCrit Project by Scott Weingart, MD FCCM.

88
article thumbnail

Variation Exists! Outcomes Exist!

EM Literature of Note

This little article has made the rounds, primarily by those who critique it for its many flaws. However, the underlying themes can still be valid, even if an article has limitations. This is a “there is variation in emergency physician admitting practices” article. Literally every practicing physician working in a hospital environment knows there is a broad spectrum of skill, approach to acute illness, and level of risk-tolerance.

article thumbnail

Prehospital Emergency Anaesthesia (PHEA) vs. Emergency Department RSI: A Comparative Study on Trauma Care Timelines and Outcomes

St. Emlyn

St.Emlyn's - Emergency Medicine #FOAMed How does pre-hospital emergency anaesthesia (PHEA) delivered by Helicopter Emergency Medical Services (HEMS) impacts trauma care timelines compared to emergency department RSI (EDRSI). The post Prehospital Emergency Anaesthesia (PHEA) vs. Emergency Department RSI: A Comparative Study on Trauma Care Timelines and Outcomes appeared first on St.Emlyn's.

article thumbnail

Get To Know: Joe McLaughlin - Senior Recruiter Permanent Placement

Core Medical Group

Meet senior recruiter from our permanent placement division, Joe McLaughlin. Joe will help you find your dream healthcare job today.

81
article thumbnail

Science-Based Satire: My Patients are Refusing the MMR Because the CDC Added the COVID Vaccine to the Routine Vaccine Schedule

Science Based Medicine

If only they had let more unvaccinated children suffer and die from COVID, we wouldn't be in this position today. The post Science-Based Satire: My Patients are Refusing the MMR Because the CDC Added the COVID Vaccine to the Routine Vaccine Schedule first appeared on Science-Based Medicine.

CDC 112