The Weekly Cheese 2.0 - Is Droperidol (still) Deadly?
Cook County EM Blog
APRIL 27, 2022
Background : Droperidol is primarily D2 antagonist used for nausea/vomiting, agitation, headache, and pain. Previously droperidol was a commonly used medication in the ED until it received a black box warning for concerns related to QT-prolongation and risk of potential fatal arrhythmias. Shortly after, the use of droperidol greatly decreased, however there is continued debate over its safety.
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