The Bottom Line

MARCH 26, 2025

Humidified Non-Invasive Ventilation versus High-Flow Therapy to Prevent Reintubation in Patients with Obesity Hernndez et al. AJRCCM 2025. DOI: 10.1164/rccm.202403-0523OC Clinical Question In obese adult patients at intermediate risk for hypoxaemic extubation failure, does non-invasive ventilation (NIV) therapy with active humidification compared to use of high-flow nasal oxygen (HFNO or HFNC) reduce all-cause reintubation within 7 days after extubation?

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Sensible Medicine

MARCH 26, 2025

I want to start a new series on Sensible Medicine. It’s called: I Learned about Medicine From That; These are first hand accounts since I started in medicine in 2005. This is about the first patient I took care of who died. -Vinay Prasad This Substack is reader-supported. To receive new posts and support our work, consider becoming a free or paid subscriber.

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Stop and Think

MARCH 26, 2025

The American College of Cardiology will meet in Chicago this weekend. The European Heart Rhythm Association gathers in Vienna. Since I was invited to EHRA, I leave for Vienna on Friday. I don’t like that the meetings conflict, but I am a heart rhythm doctor first, and a cardiologist second. ACC always features important trials. I will cover these in spoken form on the This Week in Cardiology podcast and in written form at TheHeart.org | Medscape Cardiology.

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