Tue.Jan 28, 2025

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Direct Oral Anticoagulant (DOAC) Reversal: Part 3

The Trauma Pro

In my last two posts, I reviewed some older papers on the efficacy of Andexxa (andexanet alfa) for the reversal of Factor Xa inhibitor anticoagulants. Those results were not very impressive, especially considering the high cost of this drug. In 2021, an article was published (reference 1) that performed a systematic review of the literature from 2017 to 2020.

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EM Quick Hits 62 Optimizing RSI Medication Timing, ED Boarding of Older Patients, Prolonged Tourniquet Use, Rural Peer Support Programs, ECG Reciprocal Changes, Nutrition Tips for Shift Workers

Emergency Medicine Cases

On this month's EM Quick Hits podcast: Anand Swaminathan on optimizing RSI medication timing, Brittany Ellison ED boarding challenges in older patients and solutions to ED crowding and flow, Dave Jeromeon managing prolonged tourniquet application, Nour Khatib and Phil Gillick on a rural peer support case, Jesse McLaren on ECG reciprocal changes in acute coronary occlusion, and Melody Ngon practical nutrition tips for shift workers.

EMS 94
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Hypoxia as a medicine

The Evolution & Medicine Review

Oxygen is essential for human life, yet a growing body of preclinical research is demonstrating that chronic continuous hypoxia can be beneficial in models of mitochondrial disease, autoimmunity, ischemia, and aging. This research is revealing exciting new and unexpected facets of oxygen biology, but translating these findings to patients poses major challenges, because hypoxia can be dangerous.

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Global Health in Your Own Backyard – Balancing Family, Field Work and Sustainable Practices in Rural Canada

Emergency Medicine Cases

Discover how Global EM principles can be applied to rural medicine in North America. Dr. Arjun Sithamparapillai challenges misconceptions about Global Health sustainability, and highlights the critical role of teamwork, adaptability, and equity in underserved communities. Perfect for EM professionals balancing family, career, and a passion for global impact.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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ECG of the week 29/1/2025

EMergucate

An 86yr male presents with syncope and melena. Hb 76. His ECG is below: What is the Rythm? What is you management plan for this patient?

EKG/ECG 52
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Pretibial Lacerations

Mind The Bleep

Pretibial lacerations are common injuries, especially among older adults, because the skin over the shin becomes thinner and more susceptible to tears with age. Epidemiology Pretibial lacerations may occur following minor trauma to the shin area, particularly in elderly individuals with fragile skin. The prevalence of these injuries is estimated at 5.2 per 1000 emergency department attendances in the UK (1).

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Is RFK Jr to blame for the Samoa measles outbreak? An empirical analysis of published scholarly papers and news stories

Sensible Medicine

Just out, we have a new paper on a provocative question. What factors were blamed for the 2019 Samoa measles outbreak in the peer reviewed literature and news coverage? At the time, and now 5 years later? Subscribe now First, we assembled every single peer reviewed article and mainstream media news story on the Samoa measles outbreak. 163 studies met our criteria.

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