Sensible Medicine

APRIL 14, 2024

Last week, the US FDA held a meeting to decide if a new surrogate endpoint (Minimal Residual Disease or MRD negativity) could be used to give more & faster drug approvals for patients with newly diagnosed multiple myeloma. Multiple myeloma drugs can cost $600,000 per year of treatment, but if MRD is permitted for drug approval, I suspect we will see a deluge of uncertain drugs added to the roster, and the costs per year per patient will swell to a million dollars or more.

Patient Safety 145

Patient Safety Academics Outcomes Wellness 145

Dr. Smith's ECG Blog

APRIL 14, 2024

A 56 year old male with PMHx significant for hypertension had chest pain for several hours, then presented to the ED in the middle of the night. He reported chest pain that developed several hours prior to arrival and was 5/10 in intensity. The pain was located in the mid to left chest and developed after riding his bike. There was associated fatigue when symptoms developed and mild shortness of breath at onset of chest pain however that has since resolved.

EKG/ECG 119

EKG/ECG Ultrasounds EMS Wellness 119

Taming the SRU

APRIL 14, 2024

Hernias 101 A hernia is described as, “the abnormal protrusion of abdominal contents through a defect involving the normal confines of the abdominal compartments” (9). It often involves a portion of the intestine protruding through a weak point of the abdominal wall. The location and size of the hernia often determines the symptoms and complications that a patient will present with.

Ultrasounds 93

Ultrasounds Emergency Department Pediatrics Radiology 93

Pediatric Education

APRIL 14, 2024

Patient Presentation A 5-day-old female came to clinic for their routine health supervision visit after birth. The baby was a term infant born to a 31 year old G1P1 female without problems during the pregnancy or delivery. The baby was breastfed and was doing well. The infant was not jaundiced and was eliminating well. The pertinent physical exam showed a 3.148 kg infant (25% overall, down 5% from birthweight), length 50 cm (50%), head circumference 35 cm (50%).

Pediatrics 40

Pediatrics Wellness 40

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Outcomes