Wed.Nov 22, 2023

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Propofol-related Infusion Syndrome

Don't Forget the Bubbles

One-liner… Although commonly used, Propofol can have severe adverse effects. Propofol Infusion Syndrome (PRIS) can lead to significant morbidity and mortality in children. What is Propofol? Commonly referred to as “the milk of amnesia”, propofol is a drug used for induction and maintenance of general anaesthesia and for procedural sedation. Propofol is prepared in a lipid emulsion, giving it a characteristic milky white appearance, and due to its ability to dissolve in fats, it is rapidly redist

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ACMT Toxicology Visual Pearl: Poison Dart Frog

ALiEM

The toxin from the golden poison dart frog most resembles which of the following in its mechanism of action? Botulinum toxin Bufotoxin Grayanotoxin Palytoxin Tetrodotoxin Photo adapted from Wilfried Berns (Wikimedia Commons) Reveal the Answer 3. Grayanotoxin – a sodium channel opener Background The golden poison dart frog ( Phyllobates terribilis ), often considered one of the most poisonous animals on the planet, secretes onto its skin the lipophilic alkaloid batrachotoxin , which irreversibly

Poisoning 113
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PEERS and NSAI Webinar to Strengthen CBRN-E Security in Europe

Emergency Live

Advancing European CBRN-E Preparedness and Response through Standardisation The National Standards Authority of Ireland (NSAI) and the PracticE Ecosystem for StandaRdS (PEERS) project are collaboratively hosting a webinar on December 12, 2023, titled ‘Enhancing CBRN-E Preparedness and Response Capabilities through Standardisation.’ The webinar aims to showcase ongoing European CBRN-E research and standardisation efforts, specifically focusing […] The post PEERS and NSAI Webinar

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Infection and DKA, then sudden dyspnea while in the ED

Dr. Smith's ECG Blog

To learn more about Occlusion MI, join us in this Free Webinar on November 27 12 noon US Central Time: Sign up at this link: [link] Infection and DKA, then sudden dyspnea while in the ED A 63 year old male with a PMH of CAD and peripheral vascular disease from type 1 DM presented to clinic and was found to have a very high blood sugar and so was sent to the emergency department.

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First CRISPR Treatment Approval

Science Based Medicine

The first CRISPR-based therapy approval is a milestone worthy of noting. The post First CRISPR Treatment Approval first appeared on Science-Based Medicine.

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Geriatric vs. Super-geriatric Trauma

University of Maryland Department of Emergency Med

This retrospective study looked at trauma patients over age 65 and divided them into age ranges 65-80 (geriatric) and 80 plus (super-geriatric). Th.

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Early and Empirical High-Dose Cryoprecipitate for Hemorrhage After Traumatic Injury: The CRYOSTAT-2 Randomized Clinical Trial

EM Ottawa

Methodology: 3.5/5 Usefulness: 4/5 Davenport R, et al. JAMA. 2023 Oct 12:e2321019. Editorial: Contemporary Adjuncts to Hemorrhage Control. Question and Methods: In trauma patients with major hemorrhage, does early cryoprecipitate (6g fibrinogen) administration improve survival, compared to standard care? Findings: There was no difference in all-cause mortality at 28 days (25.35 vs. 26.1%); OR 0.96 […] The post Early and Empirical High-Dose Cryoprecipitate for Hemorrhage After Traumatic In

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Eyelid Disease

Mind The Bleep

Introduction and Anatomy The eyelid is important for ensuring physical protection of the eye and maintaining lubrication over the surface of the eyeball. It is composed of five main layers (superficial to deep): skin and subcutaneous tissue, orbicularis oculi, tarsal plate, levator apparatus and conjunctiva. The meibomian glands are modified sebaceous glands that sit within the tarsal plates; they secrete oily substances onto the surface of the eye, reducing evaporation of the tear film.

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Innovation in action: e-Patient Dave’s tips on patient access and transparency in healthcare

NRC Health

Check out the Q3 snapshots highlighting how we put Human Understanding® into practice. The post Innovation in action: e-Patient Dave’s tips on patient access and transparency in healthcare appeared first on NRC Health.

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Lower vs Higher Fluid Volumes in Adult Patients With Sepsis

University of Maryland Department of Emergency Med

Building on Dr. Winter's pearl from a couple of weeks ago, this is more evidence that a one-size-fits-all approach to fluid volume for.

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Healthcare Leaders Should Focus on Making Medicine Better Rather than Issuing Press Releases on Geopolitical Issues

Sensible Medicine

We are the recipients of the curse, “may you live in interesting times.” With the wars in Ukraine and the Middle East, climate change, a global pandemic, urban gun violence, racial reckoning, the Dobbs decision, and economic disparities, among other issues, we have our share of “interesting” and divisive topics on our mind these days.