Thu.Jan 02, 2025

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Is procalcitonin "safe" to guide antibiotic use in patients with sepsis?

PulmCCM

Many randomized trials have tested the biomarker procalcitonin as a guide to de-escalate or stop antibiotic therapy in patients with known or suspected infection. A large proportion have concluded PCT is a safe and effective method to shorten antibiotic courses, including in patients with sepsis. But most such trials have been small, often single-center, and vulnerable to bias due to the unblinded nature of the intervention.

Sepsis 98
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Pre Hospital Extracorporeal CPR (ECPR) in the UK: The Sub30 study

St. Emlyn

St.Emlyn's - Emergency Medicine #FOAMed This feasibility study described the delivery of ECMO CPR (ECPR) for the first time in the UK The post Pre Hospital Extracorporeal CPR (ECPR) in the UK: The Sub30 study appeared first on St.Emlyn's.

CPR 117
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Torsade in a patient with left bundle branch block: is there a long QT? (And: Left Bundle Pacing).

Dr. Smith's ECG Blog

By Smith with comments from our electrophysiologist, Rehan Karim. (And of course Ken's comments at the bottom) An elderly obese woman with cardiomyopathy, Left bundle branch block, and chronic hypercapnea presented hypoxic with altered mental status. She was intubated. Bedside cardiac ultrasound showed moderately decreased LV function. CT of the chest showed no pulmonary embolism but bibasilar infiltrates.

EKG/ECG 87
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Reader Responds: The Intersections of Physical and Mental Health Disorders

ACEP Now

Thanks to Drs. Harrell and Bower for their excellent case discussion in the October issue of ACEP Now. They made a final diagnosis of hypertrophic obstructive cardiomyopathy and discussed how that diagnosis was made despite the initial anchoring on the wrong diagnosis. They continued to work the patient when they noted that the main presenting signtachycardiapersisted after the treatment for the initially anchored diagnosis, anxiety and panic disorder, and, possibly, hypovolemia.

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ECG Blog #463 — Lots to Explain.

Ken Grauer, MD

I was sent the ECG shown in Figure-1 told only that this tracing was obtained prior to elective electric cardioversion of a patient who had long been in persistent AFlutter ( A trial F lutter ). Serum electrolytes were normal at the time of cardioversion. The patient tolerated cardioversion well and later that day was discharged from the hospital. ( The post-cardioversion tracing will be shown momentarily in Figure-3 ).

EKG/ECG 415
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ACEP’s Emergency Medicine Data Institute Improves Patient Care

ACEP Now

To tell a story, all you need is information. To tell an accurate story, when it comes to patient care in the emergency department (ED), you need much more, according to ED data experts and emergency physicians James Augustine, MD, FACEP, and Stephen Epstein, MD, MPP, FACEP. An accurate story requires information from millions of ED visits, a way to analyze the data, and a way to use that analysis across different settings and patient populations for better outcomes.

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In Search of Motives

Sensible Medicine

This post really needs no introduction. Dr. Miller disagreed with a lot in my introduction and Dr. Ostacher’s recent piece about seeking motives for senseless acts of violence. Obviously, we at Sensible Medicine love to post well-reasoned responses to our articles. This is a great one. Adam Cifu Sensible Medicine is a reader-supported publication.

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Bubble Wrap PLUS – January 2025

Don't Forget the Bubbles

Cant get enough of Bubble Wrap? The Bubble Wrap Plus is a monthly paediatric Journal Club reading list from Professor Jaan Toelen (University Hospitals Leuven) and Dr Anke Raaijmakers (Sydney Childrens Hospital). This comprehensive list is developed from 34 journals, including major and subspecialty paediatric journals. We suggest this list can help you discover relevant or interesting articles for your local journal club or allow you to keep a finger on the pulse of paediatric research.