Mon.Oct 21, 2024

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Publication Bias and Therapeutic Fashion

Sensible Medicine

The story begins in Nottingham UK in 1980. It was a small study at one hospital. But its lessons are large. First the background. I believe the CAST trial (1991) was the most important trial in all of modern medicine. It showed that the common practice of using drugs to suppress rhythm disturbances (anti-arrhythmics) in patients after heart attack (myocardial infarction) led to higher death rates.

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Toxicology: the excuses must stop

First 10 EM

I love toxicologists, but it’s time for someone to call them out. (I also love ranting. Let’s see if I can get myself cancelled by a group of physicians that are definitely smarter than me.) I am sick of the anti-science rhetoric. Every time a toxicologist takes the stage at a conference, or grabs the […] The post Toxicology: the excuses must stop appeared first on First10EM.

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JC: AP or AL pad position for first choice shock in VF?

St. Emlyn

St.Emlyn's - Emergency Medicine #FOAMed Should we use AP or AL pad position first for defibrillation in VF/VT cardiac arrest. Critical appraisal of an observational study in JAMA suggests a better outcome with AP, but there are many biases in this study. #FOAMed @stemlyns The post JC: AP or AL pad position for first choice shock in VF? appeared first on St.Emlyn's.

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“And we’d better not risk another frontal assault. That plasmid’s dynamite.” Antivaxxers vs. plasmid DNA

Science Based Medicine

Ever since recombinant DNA has been used to develop and manufacture vaccines, antivaxxers have portrayed it as evil. This weekend, an antivaxxer decided that fear mongering about SV40 in COVID-19 vaccines wasn't enough. Here we go again. The post “And we’d better not risk another frontal assault. That plasmid’s dynamite.” Antivaxxers vs. plasmid DNA first appeared on Science-Based Medicine.

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SAEM Clinical Images Series: Not Your Average Ear Infection

ALiEM

A 5-year-old generally healthy fully immunized boy presented to the ED with worsening left ear redness, swelling, and tenderness that his family noticed the day before presentation. His family had also recently noticed an abrasion over that ear. The patient was on amoxicillin for strep throat, which was diagnosed a week before the onset of his symptoms and was improving.

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Tic Talk – A Short Primer On Tics

Don't Forget the Bubbles

Olivia, 7, has been brought to the emergency department. Over the last couple of weeks, Olivia has been having episodes of rapid blinking and grimacing. They only occur when she’s awake. She does not lose awareness, and her activities are not impaired. Olivia feels she can stop them from happening, but she feels better if she lets them happen. She is otherwise completely well.

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Medical Music Mondays: The Pinworm Shuffle

PEMBlog

Pinworms! Ahhhhh! They itch at night and they’re scary. Fortunately they are easy to treat and eradicate. They’re still gross. Lyrics [Intro] Pinworms makin me itch Pinworms son of a… WOAH! [Verse] Nocturnal anal pruritus Emergence of the white worm Even steadfast parents Are beginning to squirm But fret not and don’t cry There’s a treatment for you Pyrantel pamoate and repeat in two weeks That’s what we’ll do!

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Pediatric Scrotal Pain

EB Medicine

In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the October 2024 Pediatric Emergency Medicine Practice article, Elder Abuse and Neglect: Making the Diagnosis and Devising a Treatment Plan in the Emergency Departmen t 00:00 Welcome and Introduction 00:13 Free Subscription for Emergency Medicine Residents 01:05 Introduction to Pediatric Emergency Medicine Practice 01:37 Discussion on Acute Scrotal Pain 02:35 Testicular Torsion: Key Insights 09:50 Differential Diagnosis for Acute Scro

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What's the best method of weaning from mechanical ventilation?

PulmCCM

After more than one hundred years of use, uncertainty persists as to the ideal way to wean (or “liberate”) patients from invasive mechanical ventilation (if any such ideal exists, that is). Before extubation, a test of spontaneous breathing is performed, with either pressure-supported spontaneous breathing (in which the ventilator compensates for the difficulty of breathing through an endotracheal tube by delivering 8 cm H2O during each spontaneous breath, for example) or T-piece tri

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