The Frustration of Not Being Able to Sort Signal From Noise
Sensible Medicine
MAY 6, 2024
A treatment to reduce stroke is tested in a clinical trial. In the treatment group, 2.3% of patients had a stroke vs 2.9% in the control arm. The question that everyone wants to know is whether this -0.6% difference is signal or noise. For this, we look to the 95% confidence intervals. In the PROTECTED TAVR trial, the confidence intervals went from -1.7% (a lower stroke rate) to 0.5% (a higher rate of stroke).
Let's personalize your content