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REBEL Cast Ep116: The CLOVERS Trial – Restrictive vs Liberal Fluids in Sepsis-Induced Hypotension

RebelEM

Background: IV fluids are part of the standard resuscitation bundle in septic shock, however it is unclear if they provide a significant benefit. The goal of the trial was to see if early vasopressors improved shock control by 6 hours. This resulted in better shock control by 6hrs (76.1% Liberal: 14.9% Liberal: 14.9%

Sepsis 105
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Episode 7: Sepsis

PHEM Cast

[link] We hope you enjoyed our sepsis podcast. St Emlyns Induction podcast on Sepsis. A great summary of what to do when a patient with suspected sepsis first arrives in the ED. A great summary of what to do when a patient with suspected sepsis first arrives in the ED. March 2016.

Sepsis 52
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REBEL Cast Ep123: Reduced-Dose Systemic Peripheral Alteplase in Massive PE?

RebelEM

Click here for Direct Download of the Podcast Paper: Aykan AC et al. Because the lungs receive 100% of cardiac output, it has been hypothesized that a lower dose of thrombolytic therapy may still be effective with a better safety profile [3][4]. REBEL Cast Ep123: Reduced-Dose Systemic Peripheral Alteplase in Massive PE?

Stroke 136
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Sickle Cell Disease Module

Don't Forget the Bubbles

Symptoms may be non-specific in the beginning with patients quickly developing septic shock and disseminated intravascular coagulation. Vaccination: PCV13 (pneumococcal vaccination), meningococcal vaccines, and Hib conjugated vaccines are important to prevent life-threatening sepsis. Pneumococcal sepsis B. Pneumococcal sepsis.

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REBEL Core Cast 94.0 – SBO

RebelEM

Late findings Fever Abdominal distension (+) LR: 5.64 – 16.8 (-) LR: 0.34 – 0.43 Absent bowel sounds Peritoneal signs (i.e. rebound and guarding) Diagnostics Laboratory Tests Commonly ordered lab tests (i.e. 2.3 – 5.4) (-) LR: 0.18 (0.09 – 0.35) Ultrasound Findings Dilated loops of bowel (diameter > 2.5

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What Minimal Volume of Intravenous Fluid Challenges the Heart?

PulmCCM

’ What they found 45 critically-ill patients were included with a 28-day mortality rate of 29%; distributive shock was the most common cause of circulatory failure with sepsis being the most common cause of distributive physiology. Download his free textbook here. ED50] and in 90% [i.e.,

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Back to the BaSICS: does the infusion rate of a fluid bolus affect mortality?

PulmCCM

sepsis – defined as suspected or confirmed infection plus acute organ dysfunction; d.] Further, the Simplified Severe Sepsis Protocol [SSSP-2] , employed by Andrews and colleagues in Zambia called for an initial, therapeutic bolus at 33.3 With ANDROMEDA-SHOCK-2 enrolling patients, this distinction could become more salient.