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Recognition and Treatment of Thrombotic Thrombocytopenic Purpura

ACEP Now

1 However, many clinical features are common: more than 60 percent of patients present with a degree of neurological involvement, ranging from confusion to stroke and coma. Even relatively small amounts of anti-ADAMTS13 autoantibodies can lead to TTP. 1 Pregnant patients are particularly vulnerable to misdiagnosis of TTP in the ED.