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Should thrombolytics be given >4.5 hours after stroke onset?

PulmCCM

Patients who present with ischemic stroke more than 4.5 A new meta-analysis challenges that dogma , and makes an already challenging decision-making process even thornier for neurologists answering “code strokes” At least 8 randomized trials have been published testing IV thrombolytics given more than 4.5

Stroke 101
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Medical Malpractice Insights: Excellent documentation supports standard of care and avoids lawsuit

EMDocs

Chuck Pilcher, MD, FACEP Editor, Medical Malpractice Insights Editor, Med Mal Insights Excellent documentation supports standard of care, avoids lawsuit Vertebral artery CVA leaves patient disabled. Code Stroke is called and he is seen by a neurologist within 10 minutes. He undergoes a thrombectomy, but his outcome is poor.

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52 in 52 – #38: Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke

EMDocs

This week we cover the EXTEND trial looking at thrombolysis up to 9 hours after stroke onset. and 9 hours after onset of symptoms, with non-infarcted brain tissue, does the administration of alteplase improve functional outcome at 90 days? Intervention: Alteplase 0.9 in alteplase group versus 0.9% to 53.54, p=0.053).

Stroke 87
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Mobile Stroke Unit Propaganda Writ Large

EM Literature of Note

This is yet another one of those “Get With The Guidelines” stroke analyses, a retrospective dredge with massive imbalances between groups followed by statistical adjustments capable of turning out whichever result suits an author list with a full, dense printed page of pharma and stroke technology conflicts of interest.

Stroke 86
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Journal Feed Weekly Wrap-Up

EMDocs

. #1: Emergent Cath Lab Activations with “Normal” Computer ECG Interpretations Spoon Feed A significant minority of code STEMI patients have an initial normal computer ECG interpretation. The current analysis showed that EVT was superior in functional outcomes across a variety of ischemic severities and penumbra profiles on imaging.

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CDC gives a nudge to hospitals on sepsis care

PulmCCM

The Centers for Disease Control and Prevention formally called on hospitals to develop robust sepsis care programs to systematically identify and treat sepsis, track outcomes, and improve care delivery. Unlike strokes and STEMIs, sepsis has no gold standard for diagnosis. ” What is that, a sepsis Stasi?

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Remote Consult Protocols for Retinal Artery Occlusion: A Visionary Approach in Emergency Care?

RebelEM

hours of symptom onset appears to be the most promising approach for improving visual outcomes, supported by multiple studies and meta-analyses. What They Did: Retrospective review of consecutive RAO cases managed as part of a remote ophthalmology consult protocol activated on May 1, 2021, at three stroke centers across a health system.

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