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JAMA Pediatrics rejected our letter criticizing a study that pulled school children into the school yard and made a dog sniff them to see if they had COVID19

Sensible Medicine

We wrote this letter and submitted it to the journal, documenting that the trial violated ethical codes. Ultimately the core ethical question is, why did the authors consider this acceptable to conduct this research in children? Should they be allowed to accept unethical research on children and then block letters to the editor?

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Cerebral Edema and Diabetic Ketoacidosis: Rebaked

Pediatric EM Morsels

Kendra Jackson and Rebecca Raffler While we’ve gotten to snack on a Morsel on this subject before , new guidelines and research surrounding DKA and cerebral edema have come to light since the first go ‘round! The Pediatric Emergency Medicine Collaborative Research Commitee. Authors: Drs. Then we’ve likely got DKA. PMID: 12461495.

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Adam Cifu and Vinay Prasad are Both Wrong about A New Masking Trial

Sensible Medicine

These participants received a gift card code in this email so they could purchase a 50-pack of masks at their local pharmacy. To reiterate, the intervention was an email with instructions and a gift code. What was the outcome? The outcome was not illness. The control group was explicitly instructed not to wear masks.

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Rethinking Fluid Resuscitation in Vaso-Occlusive Crisis: Is Lactated Ringer’s the Superior Choice?

RebelEM

There has been ongoing study about the clinical significance of these effects, as well as whether and for whom LR might provide meaningfully better clinical outcomes ( Myburgh 2013 , Self 2018 , Semler 2018 , Self 2020 ). The enrollment was multicenter, large, and adequately powered for clinically meaningful changes in outcome.

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Preperitoneal Packing Vs Angioembolization: Part 3

The Trauma Pro

They separated all patients with acetabular and pelvic ring fractures using ICD-10 codes. Various hospital outcomes were tabulated, including hospital charges, mortality, and discharge location. AE and PPP have equivalent outcomes. You can feel comfortable that outcomes will be the same as AE. This is a common practice.

Fractures 113
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The COVID-OUT Trial: Does Metformin Reduce the Risk of Long COVID?

RebelEM

Background: The COVID-19 pandemic has been the focus of massive research efforts over the last three years. Outcomes: Primary: The development of long-COVID up to 300 days after enrollment. Outcomes: Primary: The development of long-COVID up to 300 days after enrollment. More research is necessary in this area.

Outcomes 140
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The DIMPLES study

Don't Forget the Bubbles

What outcomes did they look at? The patients were identified through site leads from the PERUKI research network. Was the outcome accurately measured to minimise bias? The inability to test for SARS-CoV-2 antibodies may have led to an underestimation of the impact of the virus on the reported outcomes.