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Sepsis Screening Decreases Mortality. Well, not really.

Sensible Medicine

I’ve also been attracted to the research because too often I see systems interventions adopted without data. Instead of just instituting the screening, the researchers did a cluster randomization wherein the alert was sequentially adopted. Outcomes and patients The primary outcome was 90-day in-hospital mortality.

Sepsis 98
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JAMA Pediatrics rejected our letter criticizing a study that pulled school children into the school yard and made a dog sniff them to see if they had COVID19

Sensible Medicine

We wrote this letter and submitted it to the journal, documenting that the trial violated ethical codes. Ultimately the core ethical question is, why did the authors consider this acceptable to conduct this research in children? Should they be allowed to accept unethical research on children and then block letters to the editor?

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Cerebral Edema and Diabetic Ketoacidosis: Rebaked

Pediatric EM Morsels

Kendra Jackson and Rebecca Raffler While we’ve gotten to snack on a Morsel on this subject before , new guidelines and research surrounding DKA and cerebral edema have come to light since the first go ‘round! The Pediatric Emergency Medicine Collaborative Research Commitee. Authors: Drs. Then we’ve likely got DKA. PMID: 12461495.

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Adam Cifu and Vinay Prasad are Both Wrong about A New Masking Trial

Sensible Medicine

These participants received a gift card code in this email so they could purchase a 50-pack of masks at their local pharmacy. To reiterate, the intervention was an email with instructions and a gift code. What was the outcome? The outcome was not illness. The control group was explicitly instructed not to wear masks.

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JAMA Pediatrics rejected our letter criticizing a study that pulled school children into the school yard and made a dog sniff them to see if they had COVID19

Sensible Medicine

We wrote this letter and submitted it to the journal, documenting that the trial violated ethical codes. Ultimately the core ethical question is, why did the authors consider this acceptable to conduct this research in children? Should they be allowed to accept unethical research on children and then block letters to the editor?

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Pulse oximeters overestimate O2 saturations in darker-skin patients; FDA acts (again)

PulmCCM

In 2020 during the Covid pandemic, researchers at the University of Michigan reported in a letter to the New England Journal of Medicine that in 12% of patients with darker skin, pulse oximeters overestimated their oxygen saturation, reading 92 to 96% when arterial blood gases confirmed the true value to be less than 88%. Nature (news).

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Preperitoneal Packing Vs Angioembolization: Part 3

The Trauma Pro

They separated all patients with acetabular and pelvic ring fractures using ICD-10 codes. Various hospital outcomes were tabulated, including hospital charges, mortality, and discharge location. AE and PPP have equivalent outcomes. You can feel comfortable that outcomes will be the same as AE. This is a common practice.

Fractures 113