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The Latest in Critical Care, 1/29/24 (Issue #27)

PulmCCM

Epinephrine remains the drug of choice during CPR Epinephrine remains the first-line therapy for cardiac arrest due to non-shockable rhythms (i.e., No new evidence arose to alter the usual schedule of administering 1 mg epinephrine as quickly as possible, then every 3 to 5 minutes while CPR is ongoing. PEA and asystole).

Seizures 115
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2023 AHA Update on ACLS

EMDocs

Avoid routine seizure prophylaxis in adult survivors of cardiac arrest (Level 3: no benefit), but treat seizures if they occur (Level 1: strong). For patients with OHCA, use of steroids during CPR is of uncertain benefit. Seizure prophylaxis in adult survivors of cardiac arrest is not recommended. COR 2b, LOE B-R.

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AHA/NCS Statement on Critical Care Management of Post ROSC Patients

EMDocs

The neurologic section was divided into (1) brain oxygenation, perfusion, edema, and intracranial pressure (ICP); (2) seizures and the ictal-interictal continuum (IIC); and (3) sedation and analgesia. EEG Monitoring and Seizures Statements Takeaway: If possible, obtain an EEG to evaluate for seizure activity.

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2023 AHA Update on Management Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning

EMDocs

Flumazenil administration is associated with harm in patients who are at increased risk for seizures or dysrhythmias. We recommend the use of benzodiazepines to treat seizures associated with local anesthetic systemic toxicity. Editorial Comment: Give atropine, benzo’s for seizures. COR No Benefit, LOE C-EO.

Poisoning 112
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Major Trauma – Injuries by Assault

Don't Forget the Bubbles

Other considerations in significant TBI would be the temporary use of anti-epileptic drugs as prophylaxis to prevent early post-traumatic seizures to aid neuroprotection; the most commonly used would be levetiracetam. Disability – Altered mentation, seizure, stroke symptoms, severe headache, neurological deficit, visual symptoms.

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Grand Rounds Recap 10.4.23

Taming the SRU

morbidity and mortality - quality improvement - research grand rounds - r1 clinical knowledge: pres/rcvs - r4 case follow-up: compartment syndrome Morbidity and Mortality WITH dr. finney Takotsubo Cardiomyopathy with COVID-19 Increasing incidence of Takotsubo Cardiomyopathy with the COVID-19 pandemic Morbidity and mortality is similar to that of ACS (..)

Stroke 91
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ToxCard: Benzonatate

EMDocs

She received cardiopulmonary resuscitation (CPR) and standard advanced cardiovascular life support (ACLS). Benzodiazepines are first-line therapy for seizures. Interventions are supportive including benzodiazepines for seizures, sodium bicarbonate for prolonged QRS and arrhythmias, and intravenous lipid emulsion for cardiac arrest.