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A Losartan Dream for COPD

Critical Care Now

The Pre-brief Working in a Pulmonary Function Lab plus providing in-patient care within the hospital, I see patients every day that have been diagnosed with chronic obstructive pulmonary disease (COPD). These patients frequently ask if they can be cured of COPD. COPD continues to be a problem for many adults.

COPD 52
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The Latest in Critical Care, 9/28/23 (Issue #15)

PulmCCM

Read in NEJM Prevalence of pulmonary embolism during COPD exacerbations Pulmonary embolism (PE) and acute exacerbations of chronic obstructive pulmonary disease (COPD) can present with similar symptoms of dyspnea, hypoxemia, and cough.

COPD 95
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BIPAP IPAP: Higher is Better?

EM Literature of Note

In this unblinded, randomized-controlled trial, patients with acute exacerbations of COPD received traditional NIPPV with inspiratory pressures <18 cmH20 or “high-intensity” NIPPV, with airway pressures titrated up to 20-30 cmH20. This trial, the HAPPEN trial, looks at a little bit different approach.

COPD 93
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Thyroid Storm Management

Mount Sinai EM

Considerations: If concern for severe asthma/COPD, can use cardioselective beta blocker such as metoprolol. In addition, at high doses it inhibits the conversion of T4 to T3 PO Dose: 60 to 80 mg q4-6 hr, titrated to achieve rate control while ensuring blood pressure remains stable. IV dose: 0.5

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SGEM#447: Just What I Needed – Preoxygenation Prior To Intubation

The Skeptics' Guide to EM

Case: A 70-year-old man presents to the emergency department (ED) with an exacerbation of COPD. They do not provide positive pressure or ventilatory support, and the actual FiO2 delivered can be significantly lower than expected if the mask does not fit well. He is hypoxic on arrival with an oxygen saturation of 80% on room air.

COPD 89
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BPAP vs AVAPS for Hypercapnic Respiratory Failure in the ED

RebelEM

AVAPS may be useful, but we still need a well conducted RCT to find out if it is (i.e AVAPS: 0.07 P = 0.015 PaCO2 Excretion in 1 st Hour BPAP S/T: 4.75 AVAPS: 10.20 Unfortunately, this RCT is too small with poor methodology which makes it difficult to draw any absolute conclusions. which patients and which conditions).

COPD 133
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ECG Blog #366 — Diltiazem didn't work.

Ken Grauer, MD

As a result — IF the 1 lead you are monitoring happens to be one in which P waves are not well seen — then you might assume the irregular rhythm in front of you was AFib. Applying the Above to Today's Case: In addition to being Covid-positive — the patient in today's case had longstanding COPD. Remember — 12 leads are better than one!

EKG/ECG 195