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A Losartan Dream for COPD

Critical Care Now

The Pre-brief Working in a Pulmonary Function Lab plus providing in-patient care within the hospital, I see patients every day that have been diagnosed with chronic obstructive pulmonary disease (COPD). These patients frequently ask if they can be cured of COPD. COPD continues to be a problem for many adults.

COPD 52
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A Brilliant Comment Makes the Study of the Week

Sensible Medicine

On yesterday’s podcast , I talked with Bobby Yeh, an academic cardiologist who made a compelling case for enhancing credibility of observational research. The reasons are multiple, but I will articulate a few: Most epidemiological studies are done from large data sets that are not collected for the purpose of research.

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Serial PoCUS for ED Patients with Acute Dyspnea: Is More Actually Better?

RebelEM

It can be used to distinguish between various conditions, including chronic obstructive pulmonary disease (COPD) exacerbation, acute heart failure (AHF), pleural effusion, pulmonary edema, pericardial effusion, pneumothorax, and pneumonia [2,3]. to −0.66) and −1.66 (95% CI −2.09 to −0.78) and -1.97 (95% CI −2.70 vs. 18.3%).

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Doing statistics can be difficult but understanding them can be fairly simple

Sensible Medicine

This is where we get into all the terms you see in research papers: p-values, and confidence intervals (typically 95%) – and in the media - margin of error. Inferential statistics actually do NOT help us test a research hypothesis about whether an intervention worked or not. This is the null hypothesis (no effect).

Outcomes 119
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The Latest in Critical Care, 3/25/24 (Issue #35)

PulmCCM

In a well-randomized trial, equal numbers of clinically important differences in outcomes in opposite directions could average out to a null result, hiding the variability between patients. Those trials could well suggest entirely different sets of variables that might interact to produce heterogeneity of treatment effects for oxygen.

COPD 52
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Diagnostics and Therapeutics: Managing Pneumothorax

Taming the SRU

There are many different types of pneumothorax (PTX), and the management paradigm has shifted in recent years as the research has exploded on this topic. This topic is additionally complicated by the development of multiple diagnostic tools now available for diagnosis as well as variable sizing algorithms used around the world.

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Episode 21- Updates and Controversies in the Early Management of Sepsis and Septic Shock

EB Medicine

Jeff : So as well all know Sepsis is bread and butter emergency medicine, but, what is sepsis? Optimal management of septic patients has been a source of intense research, stemming from the landmark study by Rivers in 2001. Sepsis is coming in at a higher readmission rate and cost per admission than acute MI, CHF, COPD, and PNA.

Sepsis 40