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REBEL Core Cast 122.0 – Neutropenic Fever

RebelEM

The loss of these cells leads to immunosuppression as well as decreased responsiveness of the immune system as a whole Patients with neutropenia will not only get very sick very quickly, but also will have blunted immune response and may not localize signs of infection well Fever or malaise may be their only presenting symptoms.

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EM@3AM: High Priority Fungal Pathogens and Empiric Treatment in the ED

EMDocs

Well keep it short, while you keep that EM brain sharp. Four days ago, he presented to the ED for a COPD exacerbation. Empiric treatment with voriconazole 6 mg/kg twice daily intravenously for 2 doses should be started immediately based on Infectious Disease Society of America (IDSA) guidelines.