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Rethinking the Role of TXA: Are We Asking Too Much?

RebelEM

The PATCH-trauma researchers sought to address this critique. SBP < 75 mm Hg: 39% SBP 76-89 mm Hg: 33% Critical Findings: No statistically significant difference in safety outcomes (DVT, PE, MI, Stroke) TXA Placebo RR (95% CI) Primary Outcome Good Functional Outcome (6 months) 53.7% Prehospital Tranexamic Acid for Severe Trauma.

Outcomes 105
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Grand Rounds Recap 7.31.24

Taming the SRU

to teach you and your learner something new on shift skin adhesives WITH dr. hill Dermabond is a polymer (octyl cyanoacrylate) that can be used to repair lacerations in the Emergency Department faster than sutures, allowing the ED physician to be more efficient.

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Neonatal Hypotension

Don't Forget the Bubbles

Various studies, such as those pooling data from the National Neonatal Research Database, indicate that the incidence of hypotension varies based on neonatal age, with the highest rates observed immediately post-birth and within the first days of life. CO = SV x HR SV is Stroke Volume (the amount of blood ejected with each heartbeat).

Sepsis 59
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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

MI or stroke). Secondary outcomes were early head injury related death (within 24 hours after injury), all-cause and cause-specific mortality, disability, vascular occlusive events (MI, stroke, DVT, PE), seizures, complications, neurosurgery, days of ICU care, and adverse events within 28 days. in the TXA group and 9.9%

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The AcT Trial: Tenecteplase vs Alteplase for Acute Ischemic Stroke

RebelEM

Background : Alteplase, a class of medication that converts plasminogen to plasmin leading to fibrin degradation and subsequent clot lysis, has been the standard of care for acute ischemic stroke (AIS) patients that meet eligibility criteria. mg/kg non-inferior to alteplase in the treatment of acute ischemic stroke? vs Alteplase 34.8%

Stroke 135
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Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia (MINT Trial)

RebelEM

in liberal) received a blood transfusion (2.3 These findings contrast with the results of previous transfusion trials, but it adds to the body of literature while remaining an overall negative trial. It opens the door for further research to definitively answer the question posed by this study. Circulation. Type 1: 41.7