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Best Of AAST #7: How Do You Like Your Platelets – Warm Or Cold?

The Trauma Pro

Until the last few years, massive transfusion in trauma consisted of component therapy, an admixture of packed red cells, plasma, and platelets. Whole blood transfusion is making inroads again, but it is used in a minority of centers. They identified soldiers who received either room-temperature or cold-stored platelets.

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Are we on the right TRACT? 

Don't Forget the Bubbles

Transfusion Decisions in Severe Anaemia Reducing child mortality remains high on the global health agenda. Let’s take the humble blood transfusion – used in emergency departments across the globe and playing a key role in critical care. However, there is a huge variation in transfusion practice globally. N Engl J Med.

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CRYOSTAT-2: Early Empiric Cryoprecipitate in Major Trauma

RebelEM

This would normally make me worry about dilution of results and biasing the results to the null hypothesis, but in the per protocol analysis (170 patients excluded from the full cohort, due to no longer requiring blood transfusion, dying within 90 minutes of arrival or being randomized in error) didn’t seem to affect this result either.

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NFTI And STAT: Can They Replace The Cribari Grid?

The Trauma Pro

This may be helpful for future triage-related research. They reviewed 2.5 years of their registry data (Level I center). Once again, let’s look at over- and undertriage experience in the paper: Undertriage: 9.1% undertriage (Cribari) reduced to 3.3% It also standardizes comparisons between hospitals that use STAT. What Does It All Mean?

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Rethinking the Role of TXA: Are We Asking Too Much?

RebelEM

The PATCH-trauma researchers sought to address this critique. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): A randomised, placebo-controlled trial. Article: PATCH-Trauma Investigators and ANZICS Clinical Trial Group.

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Grand Rounds Recap 7.31.24

Taming the SRU

to teach you and your learner something new on shift skin adhesives WITH dr. hill Dermabond is a polymer (octyl cyanoacrylate) that can be used to repair lacerations in the Emergency Department faster than sutures, allowing the ED physician to be more efficient.

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Vasopressor Nonresponse

Northwestern EM Blog

Those at higher risk of hypocalcemia (vitamin D deficiency, ESRD, hyperparathyroidism, burns, multiple blood transfusions, etc.) Critical Care Research and Practice. Hypocalcemia can be hinted at through history or by hints such as a prolonged QTc on an ECG. may have greater severity of shock with increased mortality.