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Sickle Cell Disease Module

Don't Forget the Bubbles

Furthermore, educating both patients and their families is important in order to achieve good treatment compliance and better clinical outcomes. Be careful if the patient has received a recent blood transfusion since it may be misinterpreted as sickle cell trait instead of sickle cell disease.

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Rethinking the Role of TXA: Are We Asking Too Much?

RebelEM

PMID: 37314244 Clinical Question: In advanced trauma systems, does prehospital administration of TXA increase the rate of survival with a favorable neurologic outcome in patients at risk for trauma-induced coagulopathy? 1.00 (0.9 – 1.12) Secondary Outcome Mortality 24h 9.7% Prehospital Tranexamic Acid for Severe Trauma.

Outcomes 105
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emDOCs Podcast – Episode 100: Acute Chest Syndrome Part 1

EMDocs

Ultrasound Sensitivity 88-100%, specificity 68-94% Positive likelihood ratio of 14.6 (95% While chest radiograph is often the first-line imaging modality, lung ultrasound has higher sensitivity and can detect pulmonary abnormalities earlier; CT imaging should be considered if initial imaging is negative or if concern for PE is present.

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Bubble Wrap PLUS – January 2024

Don't Forget the Bubbles

Lung ultrasound for the sick child: less harm and more information than a radiograph. Point-of-care ultrasound for non-vascular invasive procedures in critically ill neonates and children: current status and future perspectives. Outcomes From a Randomized Clinical Trial. Musolino AM, et al. Eur J Pediatr. 2023 Dec 22.

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emDOCs Podcast – Episode 101: Acute Chest Syndrome Part 2

EMDocs

Ultrasound Sensitivity 88-100%, specificity 68-94% LR+ of 14.6 (95% Blood transfusion Reduces the overall proportion of HbS. Markers for severe disease include hypoxemia, increasing respiratory rate or work of breathing, decreasing platelet count and/or Hb, and multilobar involvement on chest radiograph or lung ultrasound.

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SGEM386: Blood on Blood – Massive Transfusion Protocols in Older Trauma Patients

The Skeptics' Guide to EM

Massive Blood Transfusion Following Older Adult Trauma: the Effect of Blood Ratios on Mortality. Case: A […] The post SGEM386: Blood on Blood – Massive Transfusion Protocols in Older Trauma Patients first appeared on The Skeptics Guide to Emergency Medicine. Date: December 16th, 2022 Reference: Hohle et al.

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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

4] We also know that severe TBI is commonly associated with the development of intracranial hemorrhage where the presence and volume of blood are associated with increased mortality and poor outcomes.[5] Association between prehospital tranexamic acid administration and outcomes of severe traumatic brain injury. JAMA Neurol.