Don't Forget the Bubbles

JANUARY 10, 2024

Transfusion Decisions in Severe Anaemia Reducing child mortality remains high on the global health agenda. Let’s take the humble blood transfusion – used in emergency departments across the globe and playing a key role in critical care. However, there is a huge variation in transfusion practice globally.

Blood Transfusions 78

Blood Transfusions Research Outcomes Hospitals 78

EMDocs

MAY 28, 2024

Blood transfusion Reduces the overall proportion of HbS. Issues with pulse oximetry Pulse oximetry frequently underestimates the alveolar hypoxia that results in sickling and pulmonary infarction and overestimates the arterial blood oxygen saturation. Improves oxygen carrying capacity. Reduces progression to severe disease.

Blood Transfusions 85

Blood Transfusions Fluid Resuscitation Dehydration Ultrasounds 85

RebelEM

JUNE 19, 2023

Our bodies have a finely tuned system that allows blood to flow freely and not clot too easily while also allowing the body to form clots when needed. This balance is upset in trauma by loss of blood and factors, acidosis, hypothermia and the inflammatory cascade. Lancet 2010; 376(9734): 23-32.

Blood Transfusions 104

Blood Transfusions Outcomes Administration Hyperthermia / Hypothermia 104

EMDocs

JUNE 12, 2024

Previous triad of death = hypothermia, acidosis, and coagulopathy. Whole blood does contain less citrate. Liver dysfunction, secondary cirrhosis, critical illness, trauma, and hypothermia reduce citrate metabolism. Hypothermia also leads to hypoCa. Transfusion-Related Hypocalcemia After Trauma. 2011;39(1):46-54.

Hyperthermia / Hypothermia 98

Hyperthermia / Hypothermia Resuscitation Administration Blood Transfusions 98

Don't Forget the Bubbles

OCTOBER 28, 2024

To address this, there is ongoing debate about whether we should consider using a whole blood transfusion approach. Rhaenyra continues to receive blood products in a 1:1:1 ratio. After Rhaenyra’s next unit of blood transfusion is complete, you get a venous blood gas. How do we prevent hypothermia?

Blood Transfusions 72

Blood Transfusions Hyperthermia / Hypothermia Shock Pediatrics 72

Don't Forget the Bubbles

NOVEMBER 18, 2024

In these situations, it’s crucial to focus on treating the underlying respiratory issue—ensuring adequate oxygenation and ventilation and possibly using inhaled nitric oxide for pulmonary hypertension—rather than just addressing the low blood pressure. Effective management of MAS will often result in the stabilization of blood pressure.

Sepsis 59

Sepsis Shock Hyperthermia / Hypothermia Administration 59

Northwestern EM Blog

JANUARY 24, 2022

Those at higher risk of hypocalcemia (vitamin D deficiency, ESRD, hyperparathyroidism, burns, multiple blood transfusions, etc.) Hypocalcemia can be hinted at through history or by hints such as a prolonged QTc on an ECG. may have greater severity of shock with increased mortality.

Anaphylaxis 52

Anaphylaxis Shock Sepsis Resuscitation 52