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Imported Malaria

Pediatric EM Morsels

This allowed US hospitals to stock the drug to ensure quick treatment of suspected severe cases, rather than having to ship it from the CDC under the prior expanded-access protocol (Thomas 2023). Higher Rates of Misdiagnosis in Pediatric Patients versus Adults Hospitalized with Imported Malaria. Third times the charm! June 28, 2023.

Seizures 281
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What’s With Those John / Jane Doe Names?

The Trauma Pro

To expedite care, most hospitals developed a system of pseudo-names to be used until the patient can be identified. The use of Doe names in electronic health records is rapidly fading as well. The best practice for this varies by electronic record system and hospital. Originally, these names were often “Doe” names.

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The End Of Serial Hemoglobin/Hematocrit In Solid Organ Injury

The Trauma Pro

We developed our first iteration of a solid organ injury practice guideline at Regions Hospital way back in 2002. Possible interventions were none, operation, angioembolization, or blood transfusion. Here’s the final post on my series covering serial hemoglobin testing in the management of solid organ injury.

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The Latest in Critical Care, 1/8/23 (Issue #24)

PulmCCM

Smaller blood-collection tubes to reduce red blood cell transfusion (STRATUS trial) Cumulatively, daily labs on hospitalized patients deplete substantial volumes of blood, almost all of which is wasted. They have a less-powerful vacuum that removes about half as much blood per tube.

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The AcT Trial: Tenecteplase vs Alteplase for Acute Ischemic Stroke

RebelEM

What they Did : Investigator-initiated, Multicenter, Parallel-ground, Open-label, Registry-linked, Randomized, Controlled, Non-Inferiority trial 22 Canadian Primary and Comprehensive Stroke Centers from December 2019 to January 2022 Eligible ischemic stroke patients randomized 1:1 to receive intravenous tenecteplase (0.25 mg/kg followed by 0.81

Stroke 135
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ToxCard: Iron

EMDocs

5 Severe metabolic acidosis persists Multi-system organ failure The endpoints of deferoxamine are less well defined but it can be weaned off as the patient is clinically improving, the anion gap resolves, and down-trending serum iron concentration. Blood transfusion for clinically significant blood loss. Manoguerra, A.

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CRYOSTAT-2: Early Empiric Cryoprecipitate in Major Trauma

RebelEM

This would normally make me worry about dilution of results and biasing the results to the null hypothesis, but in the per protocol analysis (170 patients excluded from the full cohort, due to no longer requiring blood transfusion, dying within 90 minutes of arrival or being randomized in error) didn’t seem to affect this result either.