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Rethinking the Role of TXA: Are We Asking Too Much?

RebelEM

SBP < 75 mm Hg: 39% SBP 76-89 mm Hg: 33% Critical Findings: No statistically significant difference in safety outcomes (DVT, PE, MI, Stroke) TXA Placebo RR (95% CI) Primary Outcome Good Functional Outcome (6 months) 53.7% Read More Core EM: CRASH-2: Tranexamic Acid in Major Trauma References: CRASH-2 Trial Collaborators.

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Grand Rounds Recap 7.31.24

Taming the SRU

Can present in a delayed fashion, does not always occur immediately after pacemaker placement Delayed presentations present with signs and symptoms of cardiac tamponade in two-thirds of cases Abdominal Aortic Aneurysm Repair is usually indicated when aortic diameter is >5.5

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The AcT Trial: Tenecteplase vs Alteplase for Acute Ischemic Stroke

RebelEM

Background : Alteplase, a class of medication that converts plasminogen to plasmin leading to fibrin degradation and subsequent clot lysis, has been the standard of care for acute ischemic stroke (AIS) patients that meet eligibility criteria. mg/kg non-inferior to alteplase in the treatment of acute ischemic stroke? vs Alteplase 34.8%

Stroke 132
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Subarachnoid hemorrhage: ED presentation, evaluation, and management

EMDocs

Authors: Mikalah Ward, MD (EM Resident Physician, University of Kentucky); Susan Owens, MD (EM Attending Physician, University of Kentucky) // Reviewed by: Jessica Pelletier, DO (EM Education Fellow, Washington University in St. 12 Nicardipine is the antihypertensive agent of choice for blood pressure control in SAH.

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Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia (MINT Trial)

RebelEM

in liberal) received a blood transfusion (2.3 Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease. Third universal definition of myocardial infarction. Circulation. 2012;126(16):2020-2035. years Female sex 44.3 Baseline hemoglobin 8.6 g/dl Prior myocardial infarction 33.7

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Grand Rounds Recap 5.3.23

Taming the SRU

mg/kg of IBW Seek to match a patient's minute ventilation with TV and RR after intubation Intentionally match patient's intrinsic RR noted prior to intubation Note that healthy lungs can handle 8 mL/kg, based on IBW, if that is useful for compensation Secure your ETT Thomas Tube Holder is a new ETT holder on Air Care for ETT down to size 6.5

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ED care of refugee populations from sub-Saharan Africa

EMDocs

A whole blood transfusion is initiated for the management of her anemia. These patients suffer from untreated physical injuries, including gunshot wounds, shrapnel, accidents, envenomations, sequelae of physical or sexual assault, and heat exhaustion/heat stroke. Hypoglycemia is managed with IV dextrose.