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Systemic Steroids: An ED Focused Overview

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6 However, due to the vasoconstrictive effects, hydrocortisone may be useful in refractory shock. 12 Weight gain (up to 70%), development of cataracts (up to 15%), fractures (up to 12%), and neuropsychiatric events (up to 10%) are the most common adverse events. and cardiovascular disease (OR 1.2-2.56). 2015;116(6):960-975.