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Review of the ATHOS 3 trial

Northwestern EM Blog

Mortality benefit is an extremely elusive goal in critical care research 1 but that doesn’t discount the fact that ATHOS 3 wasn’t designed to demonstrate an improvement in any patient-oriented outcome.

Shock 52
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Grand Rounds Recap 4.19.23

Taming the SRU

EMS was bagging him on arrival Primary notable for Compromised Airway Protection, bilateral Breath sounds, strong pulses,GCS 3 CT images of Head, Chest, Abdomen, Pelvis, and Spine No acute findings pH of 6.75

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Vasopressor Nonresponse

Northwestern EM Blog

Acidosis Acidosis in shock states can present from multiple different sources, including sepsis, hypoxemia, ingestions, hyperlactatemia from hypoperfusion, amongst others. Anaphylaxis Anaphylaxis may present as hypotension alone. Hypothyroidism and Adrenal Insufficiency in Sepsis and Hemorrhagic Shock. 2008;14:379-83.

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REBEL Core Cast 122.0 – Neutropenic Fever

RebelEM

Antibiotics are effectively the only thing standing between these patients and overwhelming sepsis. Improving the immediate management of neutropenic sepsis in the UK: Lessons from a national audit. BMC Health Services Research. Neutropenic Fever: Fever (one reading of 38.3C Support Care Cancer. 2018 May;26(5):1465-1470.

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First10EM Journal Club: January 2025

Broome Docs

Adrenaline Auto-Injectors for Preventing Fatal Anaphylaxis. Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis: The ADAPT-Sepsis Randomized Clinical Trial. Full blog post here. Epipens dont work? Clin Exp Allergy. 2024 Oct 9. doi: 10.1111/cea.14565. Epub ahead of print. 2024 Dec 9. 2024.26458.

Sepsis 101