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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

We know that if administered too rapidly, it can lead to hypotension and other adverse effects including seizures, headaches, backache, abdominal pain, nausea, vomiting, diarrhea, fatigue, pulmonary embolism, deep vein thrombosis, anaphylaxis, impaired color vision, and other visual disturbances.[1] MI or stroke). Arch Surg 2012; 147:113-119.[

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TXA (Tranexamic Acid) in PediatricsĀ 

Pediatric EM Morsels

Military Application of Tranexamic Acid in TraumaEmergency Resuscitation (MATTERs) Study. of IV form TXA [O’Neill 2020] Inexpensive ! The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. 2011 Mar26;377(9771):1096-101, 1101.e1-2.