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Diagnostics: Blood Transfusion Reactions

Taming the SRU

In the era of modern medicine, blood transfusions are commonplace, especially in the emergency department. Transfusion reactions are a spectrum of adverse events that can occur with the transfusion of whole blood or any of its components. One of the major risk factors is receiving a blood transfusion in the past.

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Vasopressor Nonresponse

Northwestern EM Blog

Due to its extremely high morbidity and mortality as well as high healthcare costs, the prompt recognition, diagnosis and resuscitation of shock is key. To reverse these effects as well as refractory hypotension, hydrocortisone is the preferred agent due to both its glucocorticoid and mineralocorticoid properties.

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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

We know that if administered too rapidly, it can lead to hypotension and other adverse effects including seizures, headaches, backache, abdominal pain, nausea, vomiting, diarrhea, fatigue, pulmonary embolism, deep vein thrombosis, anaphylaxis, impaired color vision, and other visual disturbances.[1] Arch Surg 2012; 147:113-119.[

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Diagnostics: GI Bleeding

Taming the SRU

It should be made based on a balance between risk of thromboembolic events vs recurrent bleeding (risk-benefit), as well as cost-benefit. 100U (30-60 min prior), 0.25-0.375/100U 100U (30-60 min prior), 0.25-0.375/100U