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Vasopressor Nonresponse

Northwestern EM Blog

Due to its extremely high morbidity and mortality as well as high healthcare costs, the prompt recognition, diagnosis and resuscitation of shock is key. There is a subset of patients who, despite aggressive conventional resuscitation, have an inadequate hemodynamic response and develop refractory shock.

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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

We know that if administered too rapidly, it can lead to hypotension and other adverse effects including seizures, headaches, backache, abdominal pain, nausea, vomiting, diarrhea, fatigue, pulmonary embolism, deep vein thrombosis, anaphylaxis, impaired color vision, and other visual disturbances.[1] J Thromb Haemost 2019;17:852-862.[

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TXA (Tranexamic Acid) in Pediatrics 

Pediatric EM Morsels

While transfusing blood can be beneficial to those who have lost it or continue to lose it quickly, blood may not always be immediately available. Or maybe the family does not desire blood transfusions. Military Application of Tranexamic Acid in TraumaEmergency Resuscitation (MATTERs) Study.