Remove Anaphylaxis Remove Blood Transfusions Remove Outcomes
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Issue #1: The Latest in Critical Care, 5/8/23

PulmCCM

Among 1150 patients considered high risk for aspiration at 15 French hospitals, those randomized to receive remifentanil had a higher rate of severe complications of intubation (aspiration, hypoxemia, hypotension, arrhythmia, cardiac arrest, or anaphylaxis), compared to those receiving neuromuscular blockade.

Stroke 52
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Vasopressor Nonresponse

Northwestern EM Blog

Anaphylaxis Anaphylaxis may present as hypotension alone. Thus, it may easily be confused with a different form of shock and treated with vasopressors such as norepinephrine and vasopressin, which are not first line for anaphylaxis. Urticaria should prompt consideration of anaphylaxis. Understanding adrenal crisis.

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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

4] We also know that severe TBI is commonly associated with the development of intracranial hemorrhage where the presence and volume of blood are associated with increased mortality and poor outcomes.[5] Association between prehospital tranexamic acid administration and outcomes of severe traumatic brain injury. JAMA Neurol.

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Diagnostics: GI Bleeding

Taming the SRU

Ultimately, patients with variceal bleeding require endoscopic variceal ligation (EVL) but it is important to understand what therapies should be initiated promptly in the ED to improve overall outcomes. 100U (30-60 min prior), 0.25-0.375/100U