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Issue #1: The Latest in Critical Care, 5/8/23

PulmCCM

Among 1150 patients considered high risk for aspiration at 15 French hospitals, those randomized to receive remifentanil had a higher rate of severe complications of intubation (aspiration, hypoxemia, hypotension, arrhythmia, cardiac arrest, or anaphylaxis), compared to those receiving neuromuscular blockade.

Stroke 52
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Journal Club - Tranexamic Acid in Trauma

Downeast Emergency Medicine

We know that if administered too rapidly, it can lead to hypotension and other adverse effects including seizures, headaches, backache, abdominal pain, nausea, vomiting, diarrhea, fatigue, pulmonary embolism, deep vein thrombosis, anaphylaxis, impaired color vision, and other visual disturbances.[1]

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Diagnostics: Blood Transfusion Reactions

Taming the SRU

In the era of modern medicine, blood transfusions are commonplace, especially in the emergency department. Transfusion reactions are a spectrum of adverse events that can occur with the transfusion of whole blood or any of its components. One of the major risk factors is receiving a blood transfusion in the past.

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Diagnostics: GI Bleeding

Taming the SRU

100U (30-60 min prior), 0.25-0.375/100U

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TXA (Tranexamic Acid) in Pediatrics 

Pediatric EM Morsels

While transfusing blood can be beneficial to those who have lost it or continue to lose it quickly, blood may not always be immediately available. Or maybe the family does not desire blood transfusions. Tranexamic Acid Use in United States Children’s Hospitals. 2010Jul 03;376(9734):23-32. J Emerg Med.