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Anaphylactic Shock

RebelEM

Anaphylactic Shock is an acute, life-threatening hypersensitivity disorder, with a generalized, rapidly evolving, multi-systemic allergic reaction (IgE-mediated disorder). Anand Swaminathan, MD and I wrote the anaphylactic shock chapter and with Scott’s permission are publishing it here as FOAM.

Shock 145
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Allergy emergency: anaphylactic anti-shock drugs are missing

Emergency Live

New allergist task force in action The shortage of adrenaline self-injectors, essential life-saving drugs to counter anaphylactic shocks, is taking on alarming proportions in Italy.

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Adrenaline nasal spray: the revolution against allergic shock

Emergency Live

FDA approved the first adrenaline-based nasal spray used to treat anaphylactic shock An epochal breakthrough in the management of severe allergic reactions has been announced by the US Food and Drug Administration (FDA).

Shock 52
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AED Accessories: The Importance of High-Quality Defibrillator Pads

AED Leader

These pads deliver an electric shock to the heart to restore its normal rhythm during sudden cardiac arrest. When the AED analyzes the heart’s rhythm and determines the need for defibrillation, it sends an electrical shock through the pads to the heart, allowing it to regain its normal function.

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Anaphylaxis, chest pain, and ST elevation in aVR

Dr. Smith's ECG Blog

Sent by anonymous, written by Pendell Meyers A man in his late 40s presented to the ED with concern for allergic reaction after accidentally eating a potential allergen, then developing an itchy full body rash and diarrhea. In the ED he received methylprednisolone, diphenhydramine, and epinephrine for possible anaphylaxis.

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STREAM-2: Half-Dose Tenecteplase vs Primary PCI in Older Patients with STEMI?

RebelEM

The STREAM-1 trial found that for [2] patients with STEMI presenting within 3 hours of symptom onset and unable to attain PCI within 1 hour of first medical contact, a pharmaco-invasive strategy resulted in similar rates of death, shock, heart failure, or reinfarction compared to primary PCI. Primary PCI: 95.7% Primary PCI: 95.7%

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Nephrotic Syndrome

Mind The Bleep

Steroid resistance Failure to achieve complete remission after 8 weeks of prednisolone at 60mg/m2/day Differentials Heart failure – would present with oedema, shortness of breath, cyanosis Allergic reaction – presents with facial oedema, pruritus.