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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Health care professional involved in patient management and outcome assessment was completely blinded. Patients were randomized in a 1:1 ratio. Allergy Asthma Proc. PMID: 17883909.