Remove Allergic Reactions Remove Hospitals Remove Outcomes
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STREAM-2: Half-Dose Tenecteplase vs Primary PCI in Older Patients with STEMI?

RebelEM

In non-PCI-capable hospitals this goal is not always achievable due to delays in transfer. Background: Primary PCI is the recommended reperfusion strategy in patients with STEMI and should be initiated within 2 hours after first medical contact. In these cases, thrombolysis is recommended to improve morbidity and mortality. Primary PCI: 95.7%

EKG/ECG 137
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Toss Up: A Little Bleeding, or A Lot of Platelets

EM Literature of Note

Platelets, like any blood product, are associated significant risks, not limited to acute lung injury, transfusion-related circulatory overload, allergic reactions, and more. The primary outcome was CVC-related bleeding, graded on a scale of 0 to 4, where Grade 3 and 4 bleeding was associated with significant intervention.

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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Health care professional involved in patient management and outcome assessment was completely blinded. The effectiveness of IV cetirizine was determined to be statistically non-inferior.

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Episode 20 - Emergency Department Management of North American Snake Envenomations

EB Medicine

Nachi: Not only are they out, they actually worsen outcomes, so definitely don’t pursue any of them. Instead, since no treatment has been shown to improve outcome, you should prioritize prompt transport. Fasciotomies have not been shown to improve outcomes and are reserved only for those failing anti-venom treatment.

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What the Emergency Clinician Must Know about Remote Monitors in Heart Failure

EMDocs

The goal of these devices is to detect a heart failure decompensation early and to reduce hospital admissions. 2 These implantable devices offer physiological parameters to direct therapies and reduce hospitalizations. The device group experienced 39% fewer HF hospitalizations over the study period.

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The PALACE Trial: Direct Oral PCN Challenge in Patients with Low-Risk PCN Allergy?

RebelEM

Literature including patients with penicillin allergies also show longer, more complicated hospital courses. Background: Many patients report a vague history of penicillin allergy. The vast majority of these self-reported allergies are untrue (< 5%) . randomization) as per protocol (i.e. randomization) as per protocol (i.e.

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How Many COVID Vaccines Are Enough?

Sensible Medicine

The predictable outcome has been mass hysteria. How often will vaccination prevent hospitalization and death? Direct evidence on hard clinical outcomes is needed. Fortunately, his condition improved and the topic was not revisited. The politicization of COVID science has rendered objective public education an impossibility.

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