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Allergic Reactions and Anaphylaxis

EB Medicine

— In this episode, Sam Ashoo, MD, and TR Eckler, MD, discuss the July 2022 Emergency Medicine Practice article on the Management of Allergic Reactions and Anaphylaxis in the Emergency Department. Intro The number of ED visits and hospitalizations Studies show up to 57% of anaphylactic reactions are not recognized, and epinephrine is not administered (..)

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Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

RebelEM

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. antibiotics, NSAIDs) Acute urticaria with angioedema or anaphylaxis provided that urticaria was still present after initial treatment and alleviation of anaphylaxis symptoms.

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Episode 20 - Emergency Department Management of North American Snake Envenomations

EB Medicine

Nachi: Right, but in Australia, not only are the snakes more venomous but the hospital transport distances are much longer, so, basically they sacrifice the limb to potentially save a life. Note that antivenom will NOT reverse anaphylaxis on its own. Regardless, the treatment is the same – epinephrine.

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ToxCard: Crotalid Envenomation Part 2 – CroFab vs. AnaVip: What’s the Difference?

EMDocs

Case, continued: A 2-year-old boy was admitted to your hospital in stable condition after a copperhead snake bite to the right lower leg. He was administered 10 vials of Crotalidae equine immune F(ab’) 2 (ANAVIP®) at the outside hospital before transfer to your referral center. Table 1: Comparison of F(ab) and F(ab’) 2 antivenoms.

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The PALACE Trial: Direct Oral PCN Challenge in Patients with Low-Risk PCN Allergy?

RebelEM

Literature including patients with penicillin allergies also show longer, more complicated hospital courses. Background: Many patients report a vague history of penicillin allergy. The vast majority of these self-reported allergies are untrue (< 5%) . randomization) as per protocol (i.e. randomization) as per protocol (i.e.